Gene therapy company inks strategic partnership with animal health firm to develop ‘one-dose’ injection treatment for canine osteoarthritis.
Category: biotech/medical – Page 572
Gallbladder Cancer Treatment
Posted in biotech/medical
Types of treatment for gallbladder cancer include surgery, radiation, and chemotherapy. Treatment of gallbladder cancer that has spread to other parts of the body, cannot be removed by surgery, or has come back after treatment is often within a clinical trial. Find out about treatment options for gallbladder cancer.
A UC Davis Health study found that a single dose of Bacillus Calmette-Guérin (BCG), the vaccine for tuberculosis (TB), reduced liver tumor burden and extended the survival of mice with liver cancer. The study, published in Advanced Science, is the first to show the promising effects of the vaccine in treating liver cancer.
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is also the third leading cause of cancer-related deaths worldwide. Current therapies include surgery, radiotherapy, chemotherapy, immunotherapy and liver transplant. Yet, the therapy outcomes for liver cancer remain bleak.
BCG, the century-old TB vaccine, is derived from the live bacteria Mycobacterium bovis. It is considered safe and widely used around the world.
A few years ago, a team of researchers working under Professor Stanisa Raspopovic at the ETH Zurich Neuroengineering Lab gained worldwide attention when they announced that their prosthetic legs had enabled amputees to feel sensations from this artificial body part for the first time.
Unlike commercial leg prostheses, which simply provide amputees with stability and support, the ETH researchers’ prosthetic device was connected to the sciatic nerve in the test subjects’ thigh via implanted electrodes.
This electrical connection enabled the neuroprosthesis to communicate with the patient’s brain, for example relaying information on the constant changes in pressure detected on the sole of the prosthetic foot when walking. This gave the test subjects greater confidence in their prosthesis—and it enabled them to walk considerably faster on challenging terrains.
An innovative computer model of a human lung is helping scientists simulate, for the first time, how a burst of radiation interacts with the organ on a cell-by-cell level.
This research, carried out at the University of Surrey and GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, could lead to more targeted treatments for cancer and reduce the damage caused by radiotherapy. The research is published in the journal Communications Medicine.
Dr. Roman Bauer, Senior Lecturer at the University of Surrey, said, “Doctors could one day use our model to choose the right length and strength of radiotherapy—tailored to their patient. This is exciting enough—but others could use our technique to study other organs. This could unlock all kinds of medical knowledge and could be great news for doctors and future patients.”
Drugs blocking dopamine transporters may be harmful for healthy teens but helpful for those with pathological dopamine hypofunction.
In a breakthrough finding researchers at Columbia University Irving Medical Center identified a sensitive developmental period during adolescence that impacts adult impulsivity, aggression, and dopamine function in mice.
As organisms grow from embryo to adult, they pass through sensitive time periods where developmental trajectories are influenced by environmental factors. These windows of plasticity often allow organisms to adapt to their surroundings through evolutionarily selected mechanisms.
Einstein scientist Xingxing Zang, Ph.D., has teamed up with Einstein grad, Elizabeth Stoner, M.D.
Albert Einstein College of Medicine researcher Xingxing Zang, Ph.D., latest cancer research and clinical trial.
New CDC data updated Friday shows 25 states are experiencing ‘high’ or ‘very high’ levels of respiratory illness activity.
1.6 billion people globally are homeless.
Homelessness has been a growing issue in the United States for decades — it affects millions of people each year. Despite efforts to address the problem, the number of individuals experiencing homelessness continues to rise, with the COVID-19 pandemic and an ongoing lack of affordable housing exacerbating an already difficult situation.
Tufts University School of Medicine researchers developed imaging technology that records neuronal activity throughout the brain during the first weeks of recovery. They discovered that a head injury serious enough to affect brain function, such as that caused by a car accident or sudden fall, leads to changes in the brain beyond the site of impact. In an animal model of traumatic brain injury, the researchers found that both hemispheres work together to forge new neural pathways in an attempt to replicate those that were lost.
Their findings are published in Cerebral Cortex in an article titled, “Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model.”
“Traumatic brain injury (TBI) is the leading cause of death in young people and can cause cognitive and motor dysfunction and disruptions in functional connectivity between brain regions,” wrote the researchers. “In human TBI patients and rodent models of TBI, functional connectivity is decreased after injury. Recovery of connectivity after TBI is associated with improved cognition and memory, suggesting an important link between connectivity and functional outcome. We examined widespread alterations in functional connectivity following TBI using simultaneous widefield mesoscale GCaMP7c calcium imaging and electrocorticography (ECoG) in mice injured using the controlled cortical impact (CCI) model of TBI.”