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Category: biotech/medical – Page 558

Science: Research suggest that dinosaurs 🩕 🩖 may have influenced how humans age today.

Human aging may have been influenced by millions of years of dinosaur domination according to a new theory from a leading aging expert. The ‘longevity bottleneck’ hypothesis has been proposed by Professor Joao Pedro de Magalhaes from the University of Birmingham in a new study published in BioEssays. The hypothesis connects the role that dinosaurs played over 100 million years with the aging process in mammals.

While some reptiles and amphibians show no significant signs of aging, all mammals—including humans—show a marked .

Professor de Magalhaes’ hypothesis suggests that during the Mesozoic Era, mammals faced persistent pressure for rapid reproduction during the reign of dinosaurs, which over 100 million years led to the loss or inactivation of genes associated with , such as processes associated with tissue regeneration and DNA repair.

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In a new study using brain scans of former NFL athletes, Johns Hopkins Medicine researchers say they found high levels of a repair protein present long after a traumatic brain injury such as a concussion takes place. The repair protein, known as 18 kDa translocator protein (TSPO), is known to be present in the brain at high levels in the immediate aftermath of brain injury as part of the inflammatory response and to facilitate repair. The new findings, published Oct. 30 in JAMA Network Open, suggest that brain injury and repair processes persist for years after players end collision sports careers, and lead to long-term cognitive problems such as memory loss.

“The findings show that participating in repeated collision sports like football may have a direct link to long-term inflammation in the brain,” says Jennifer Coughlin, M.D., associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. Ongoing studies like the current one, she says, add details about how the brain heals — or doesn’t — and how repeated brain injuries, even mild ones that players routinely shake off, may over time affect cognitive abilities.

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Learn more about Clinical Trials and Immunotherapy for Head and Neck Cancer. Featuring speakers: Dan Paul Zandberg, MD (Director, Head and Neck and Thyroid Cancer Disease Sections, Division of Hematology and Oncology, UPMC Hillman Cancer Center), Ricardo Zwirtes, MD (VP, Clinical Development, SQZ Biotechnologies), Jeffery Shoop (Two-Time Head and Neck Cancer Survivor. (Presented by SQZ Biotechnologies, SPOHNC and Head and Neck Cancer Alliance)

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Engineered immune cells have demonstrated great efficacy in lymphoma but not in solid tumors. On Oct 13th, 2021, two experts described recent advances in the development of CAR therapy for solid tumors.

Tamara Laskowski, PhD, Scientific Project Director of the CAR NK Program, Adoptive Cell Therapy Platform at the MD Anderson Cancer Center discussed “Engineering off-the-shelf CAR immune cells”.

Maik Luu, PhD, Project Principal Investigator at the University Hospital WĂŒrzburg, presented her results on “Improving CAR T therapy efficacy with the gut microbiome”.

BPS Bioscience CAR T-Cell Therapy Products: https://bpsbioscience.com/research-areas/car-t.

More about CAR T-Cell Therapy: https://bpsbioscience.com/car-t-cell-therapy-technical-note.

LinkedIn: https://www.linkedin.com/company/bps-bioscience-inc/

Continue reading “Penetrating Solid Tumors with CAR Immune Cells” | >

The Lung Cancer Webinar Series Presentation held on August 31, 2022 on “Treatment of Unresectable Stage 3 Non-Small Cell Lung Cancer” moderated by: Hatim Husain, M.D., Medical Oncologist, Associate Professor of Medicine, UC San Diego Health and discussants: Edward B. Garon, M.D., MS, Professor of Medicine at David Geffen School of Medicine, UCLA Department of Medicine, Division of Hematology/Oncology and Aaron E. Lisberg, M.D., Assistant Clinical Professor at David Geffen School of Medicine, UCLA Department of Medicine, Division of Hematology/Oncology.

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When a biolab owned by several Chinese nationals was discovered in the small town of Reedley, California, there was outrage that such a thing was going on without officials knowing anything about it. Unfortunately, that was the least of what Americans should be outraged about. In this episode of China Uncensored, we look at the CDC and FBI’s unbelievable responses, why the substances in the biolab were never tested, and how similarly shady behavior by the US government in regards to Chinese biolabs should make every American fear for their life.

How China Will Create The NEXT Pandemic https://www.youtube.com/watch?v=nVPmFFQBRaY&ab_channel=ChinaUncensored.

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Continue reading “SHOCKING REVELATIONS in Illegal Chinese Biolab Found in California” | >

The major phenotypes of inflammatory bowel disease (IBD) include ulcerative colitis (UC) and Crohn’s disease (CD), which cause debilitating symptoms, including bloody diarrhea, abdominal discomfort, and fever. Patients require life-long immunosuppressive medications, which cause adverse side effects as additional morbidity factors. However, IBD is initiated and perpetuated by inflammatory cytokines, and given that in patients with IBD myeloid lineage leukocytes are elevated with activation behavior and release inflammatory cytokines, selective depletion of elevated granulocytes and monocytes by granulomonocytapheresis is a relevant therapeutic option for IBD patients.

Therefore, a column filled with specially designed beads as granulomonocytapheresis carriers for selective adsorption of myeloid lineage leukocytes (Adacolumn) has been applied to treat patients with active IBD.

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A speech prosthetic developed by a collaborative team of Duke neuroscientists, neurosurgeons, and engineers can translate a person’s brain signals into what they’re trying to say.

Appearing Nov. 6 in the journal Nature Communications, the new technology might one day help people unable to talk due to neurological disorders regain the ability to communicate through a brain-computer interface.

“There are many patients who suffer from debilitating motor disorders, like ALS (amyotrophic lateral sclerosis) or locked-in syndrome, that can impair their ability to speak,” said Gregory Cogan, Ph.D., a professor of neurology at Duke University’s School of Medicine and one of the lead researchers involved in the project. “But the current tools available to allow them to communicate are generally very slow and cumbersome.”

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Continue reading “Longevity-Associated Triglycerides” | >