Changes to short, repetitive sequences in the genome have been linked to diseases like autism and schizophrenia. New revelations about how such changes increase and decrease gene expression may provide insight into these and other disorders.
Category: biotech/medical
For many patients diagnosed with certain types of B-cell lymphoma, leukemia and multiple myeloma, chimeric antigen receptor (CAR) T cell therapy offers an effective treatment option. This cellular therapy is created by extracting a patient’s T cells, modifying them in a lab to identify and attack cancer cells, and returning them to the patient.
The process of creating the CAR T cells can take three to four weeks. Radiation therapy can be a tool to help get a patient through this manufacturing period. This is called bridging therapy.
“Bridging therapy can help control the disease so that a patient can get to the CAR T cell infusion,” says radiation oncologist Penny Fang, M.D. Research from Fang and her colleagues examines the role of bridging therapy for B-cell lymphoma patients receiving CAR T cell therapy. Their latest findings will be presented at the 2023 American Society for Radiation Oncology Annual Meeting.
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Neurosurgeons can leave the operating room more confident today than ever before about their patient’s brain tumor diagnosis, thanks to the integration of a new system that employs optical imaging and artificial intelligence that are making brain tumor diagnosis quicker and more accurate. This technology is allowing them to quickly see diagnostic tissue and tumor margins in near-real time.
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Pat Bennett’s prescription is a bit more complicated than “Take a couple of aspirins and call me in the morning.” But a quartet of baby-aspirin-sized sensors implanted in her brain are aimed at addressing a condition that’s frustrated her and others: the loss of the ability to speak intelligibly. The devices transmit signals from a couple of speech-related regions in Bennett’s brain to state-of-the-art software that decodes her brain activity and converts it to text displayed on a computer screen.
Bennett, now 68, is a former human resources director and onetime equestrian who jogged daily. In 2012, she was diagnosed with amyotrophic lateral sclerosis, a progressive neurodegenerative disease that attacks neurons controlling movement, causing physical weakness and eventual paralysis.
Our brains remember how to formulate words even if the muscles responsible for saying them out loud are incapacitated. A brain-computer hookup is making the dream of restoring speech a reality.
The recreation of the human brain is giving clues to essentially how we engineer a super brain someday 😀.
Nobody’s quite sure what it means yet. But we’re sure that it’s important.
This is leading to even better brain engineering 👏 🙌 👌 😀 😄.
Computer-augmented brains, cures to blindness, and rebuilding the brain after injury all sound like science fiction. Today, these disruptive technologies aren’t just for Netflix, “Terminator,” and comic book fodder — in recent years, these advances are closer to reality than some might realize, and they have the ability to revolutionize neurological care.
Neurologic disease is now the world’s leading cause of disability, and upwards of 11 million people have some form of permanent neurological problem from traumatic brain injuries and stroke. For example, if a traumatic brain injury has damaged the motor cortex — the region of the brain involved in voluntary movements — patients could become paralyzed, without hope of regaining full function. Or some stroke patients can suffer from aphasia, the inability to speak or understand language, due to damage to the brain regions that control speech and language comprehension.
Thanks to recent advances, sometimes lasting neurologic disease can be prevented. For example, if a stroke patient is seen quickly enough, life-threatening or-altering damage can be avoided, but it’s not always possible. Current treatments to most neurologic disease are fairly limited, as most therapies, including medications, aim to improve symptoms but can’t completely recover lost brain function.
Could changing your diet play a role in slowing or even preventing the development of dementia? We’re one step closer to finding out, thanks to a new UNLV study that bolsters the long-suspected link between gut health and Alzheimer’s disease.
The analysis — led by a team of researchers with the Nevada Institute of Personalized Medicine (NIPM) at UNLV and published this spring in the Nature journal Scientific Reports — examined data from dozens of past studies into the belly-brain connection. The results? There’s a strong link between particular kinds of gut bacteria and Alzheimer’s disease.
UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.
The University of Alberta is 3rd in the world for AI research.
Researchers meet the challenge of developing a model that uses speech traits to detect cognitive decline, paving the way for a potential screening tool.
Researchers are striving to make earlier diagnosis of Alzheimer’s dementia possible with a machine learning (ML) model that could one day be turned into a simple screening tool anyone with a smartphone could use.
The model was able to distinguish Alzheimer’s patients from healthy controls with 70 to 75 per cent accuracy, a promising figure for the more than 747,000 Canadians who have Alzheimer’s or another form of dementia.
Hearing diminishes as we age — about 50% of adults 75 and over in the United States have disabling hearing loss.
Age-related hearing loss cannot currently be stopped.
Researchers from the University of Guelph and Tufts.
University/Fatty Acid Research Institute have found a link between increased omega-3 fatty acids in the blood and less age-related hearing issues.
As we age, it is not uncommon for the effectiveness of some of our sensesTrusted Source — including vision, hearing, and tasteTrusted Source — to decrease.