AstraZeneca Plc shares rose after trial data showed Tagrisso slowed disease progression in patients with advanced lung cancer in another win for the pharmaceutical giant’s blockbuster drug.
Category: biotech/medical – Page 537
Excess amounts of vitamin B3 — which is found in meat, fish, nuts, and fortified cereals and breads — may trigger inflammation and damage blood vessels.
Genetic Engineering and DNA alteration is an emerging technology with huge ramifications in the future, including potentially altering the DNA of adult humans, not just embryos or plants \& animals.
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Credits:
DNA Manipulation in Living Subjects (original title)
Genetically Altering Living Organisms.
Episode 227; Feb 27, 2020
Writers:
Isaac Arthur.
Editors:
Study uses AI and blood samples from 50,000 to predict dementia 15 years in advance, offering hope for early intervention.
A team of researchers in Spain has achieved a breakthrough by capturing the world’s first detailed images of a human cell’s ‘highway network’ beginning to emerge.
The high-resolution images and atomic-scale film help explain a longstanding puzzle of how small structures called microtubules form during cell division. The discovery could progress the development of targeted treatments for cancer, and many other conditions.
“Microtubules are critical components of cells, but all the images we see in textbooks describing the first moments of their creation are models or cartoons based on structures in yeast,” says biochemist Thomas Surrey from the Centre for Genomic Regulation in Barcelona.
In this Mini Review, the authors discuss the relationship between condensate formation, genome organization, and transcriptional activity, focusing on the experimental evidence behind the role of transcriptional condensates in gene regulation.
For patients with acute ischemic stroke and large cores, endovascular thrombectomy (EVT) improves clinical outcomes compared with medical management (MM), according to a study published online Feb. 7 in the Journal of the American Medical Association to coincide with the annual American Stroke Association International Stroke Conference, which was held from Feb. 7 to 9 in Phoenix.
Amrou Sarraj, M.D., from Case Western Reserve University in Cleveland, and colleagues describe the relationship between imaging estimates of irreversibly injured brain and at-risk regions and clinical outcomes and EVT treatment effect in an exploratory analysis of the SELECT2 trial.
Adults with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery (M1 segment) and large ischemic core were randomly allocated to EVT versus MM across 31 global centers; the analysis included 336 patients.
It is often thought that if we cure aging or find out how to upload a human mind that humans will be immortal. Today we will examine that notion and see how well it holds up against astronomical time lines.
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Cover Art by Jakub Grygier: https://www.artstation.com/artist/jak…
Graphics Team:
Edward Nardella.
Jarred Eagley.
Justin Dixon.
Katie Byrne.
Kris Holland of Mafic Stufios: www.maficstudios.com.
Misho Yordanov.
Pierre Demet.
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Stefan Blandin.
Script Editing:
Andy Popescu.
Connor Hogan.
Edward Nardella.
Eustratius Graham.
Gregory Leal.
Jefferson Eagley.
Luca de Rosa.
Mark Warburton.
Michael Gusevsky.
Mitch Armstrong.
MolbOrg.
Naomi Kern.
Philip Baldock.
Sigmund Kopperud.
Steve Cardon.
Tiffany Penner.
Music:
Markus Junnikkala, \
Around one-fifth of the stem cells grown in laboratories for as-yet-unapproved medical treatments have cancer-causing mutations.
By Clare Wilson
How does our intestine, which can be at least 15 feet long, fit properly inside our bodies? As our digestive system grows, the gut tube goes through a series of dramatic looping and rotation to package the lengthening intestine. Failure of the gut to rotate properly during development results in a prevalent, but poorly understood, birth anomaly called intestinal malrotation.
Now, in a study published in the journal Development, scientists from North Carolina State University have uncovered a potential cause of this life-threatening condition.
Intestinal malrotation affects 1 in 500 births but the underlying causes are not well understood. To find out why gut revolution could go amiss, scientists need to first understand intestinal rotation during normal development, a complex process that still baffles biologists.