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Category: biotech/medical – Page 536

US biotech Immunis has developed an “immunomodulatory secretome” technology targeting age-related immune decline. With preclinical studies showing benefit in muscular atrophy, metabolic and vascular function, tissue inflammation, and immune cell function in a range of age-related disease indications, the Californian company is currently engaged in its first in-human clinical trial for muscle atrophy.

Longevity. Technology: The secretome refers to the substances that are secreted (released) by cells – exosomes, micro-vesicles, proteins, growth factors, hormones, cytokines, and other substances. The secretome is known to play a role in helping repair and regenerate our bodies, but these beneficial secreted factors decline with age. Immunis has developed a novel method to isolate secreted cellular factors that benefit immune system development, modulation, and health – and replenish them. To find out more about the company and its technology, we spoke to its Chairman, Dr Hans Keirstead.

Keirstead is a renowned stem cell expert and serial entrepreneur, founding and successfully exiting several biotech companies in the stem cell space. Back in the early days of the field, he became the first neuroscientist in the world to work with human stem cells.

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We take a look at how the latest advancements in artificial intelligence are impacting modern medicine and theorize about what the future may hold.

Continue reading “Artificial Intelligence Shaping the Future of Medicine” | >

Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This study suggests new avenues to improve liver cancer treatment.

The liver is a vital organ with many important functions in the body. It metabolizes nutrients, stores energy, regulates the blood sugar level, and plays a crucial role in detoxifying and removing harmful components and drugs. Liver cancer is one of the world’s most lethal types of cancer. Conditions that cause liver cancer include obesity, and hepatitis C infection. Early diagnosis and appropriate therapeutic strategies are crucial for improving treatments in .

In the past decade, scientists have made much progress in understanding the multiple facets of cancer. Historically, it has long been viewed as a disorder in . However, there is growing evidence that cancer is a .

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A cyclist who was paralysed in an accident is able to walk again, thanks to a breakthrough in neurosurgery and artificial intelligence in Switzerland.
Al Jazeera’s Andrew Simmons reports.

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Transcatheter repair

A transcatheter repair, also called transcatheter device closure, is usually recommended for an atrial septal defect. During this procedure, a pediatric interventional cardiologist makes an incision in the groin, inserts a catheter, and funnels a small mesh patch through the catheter and up to the hole in the heart. Over time, the child’s own heart tissue grows over the patch.

Learn more about atrial septal defect transcatheter repair for children.

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America in the near future has lost the war against drugs. Paranoia reigns as 2 out of every 10 Americans have been hired by the government to spy on the other 8 in the name of national security and drug enforcement. Enter Fred, a reluctant undercover cop recruited by the government. To maintain his cover, Fred regularly ingests the popular Substance D. The drug has caused Fred to develop a split personality, of which he is unaware; his alter ego is Bob Arctor, a drug dealer. Fred’s superiors set up a hidden holographic camera in his home as part of a sting operation to snare Bob. A “scramble suit” that changes his appearance allows Fred to appear on camera as Bob and prevents his colleagues from knowing his true identity. The camera in Fred/Bob’s apartment reveals that Bob’s friends regularly betray one another for the chance to score more drugs.

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Continue reading “Higher HRV, Lower RHR: Potential Impacts For Weight Loss And Consistent Exercise Training” | >

Paul Bunn, MD, University of Colorado Cancer Center, Aurora, CO, discusses the survival rates of patients with stage IV lung cancer, which remain suboptimal. For patients who have a high PD-L1 tumor proportion score (TPS), approximately a third of patients survive 5 years after initial diagnosis, and further statistical analysis is required to assess whether co-morbidities contribute to patient mortality after the 5 year mark. Despite the lack of available therapies for patients with late stage lung cancer, Prof. Bunn highlights treatment options for early stage lung cancer including immunotherapy and tyrosine kinase inhibitors (TKIs) for patients with driver mutations. This interview took place at the 2022 Targeted Therapies of Lung Cancer Meeting (TTLC 2022).

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Imagine that a soldier has a tiny computer device injected into their bloodstream that can be guided with a magnet to specific regions of their brain. With training, the soldier could then control weapon systems thousands of miles away using their thoughts alone. Embedding a similar type of computer in a soldier’s brain could suppress their fear and anxiety, allowing them to carry out combat missions more efficiently. Going one step further, a device equipped with an artificial intelligence system could directly control a soldier’s behavior by predicting what options they would choose in their current situation.

While these examples may sound like science fiction, the science to develop neurotechnologies like these is already in development. Brain-computer interfaces, or BCI, are technologies that decode and transmit brain signals to an external device to carry out a desired action. Basically, a user would only need to think about what they want to do, and a computer would do it for them.

BCIs are currently being tested in people with severe neuromuscular disorders to help them recover everyday functions like communication and mobility. For example, patients can turn on a light switch by visualizing the action and having a BCI decode their brain signals and transmit it to the switch. Likewise, patients can focus on specific letters, words or phrases on a computer screen that a BCI can move a cursor to select.

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