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Category: biotech/medical – Page 520

Northeastern researchers identify proteins receptive to treating ovarian cancer

Researchers at Northeastern University have identified two proteins abundant on drug-resistant ovarian cancer cells that become receptive to chemotherapy when treated with light.

Published in the journal Photochemistry and Photobiology, the research findings represent promising progress in the treatment of one of the most deadly forms of cancer. By targeting cancer cells with photo-sensitive antibodies and then shining light on them, researchers have made previously untreatable tumors receptive to drugs.

(This may be a repost, but still cool. Reposts are cool because it is a sign of something to pay attention to.)

Researchers have developed a light-based ovarian cancer therapy that makes tumors more receptive to chemotherapy.

Exercise and the Organ-Brain Axis: Regulation of Neurological Disorders by Emerging Exerkines

Research on exercise and brain disorders has traditionally focused on its direct regulatory effects on neurons and synapses, neglecting peripheral organ-mediated pathways. To address this gap, this review proposes the novel concept of the “multi-organ-brain axis.” This concept posits that during brain disorders, functional alterations in peripheral organs such as skeletal muscle, heart, liver, adipose tissue, and spleen can disrupt metabolic and immune homeostasis, thereby bidirectionally modulating brain function via signaling molecules and metabolites.

The first 25 years of SuperAger research show cognitive decline is not an inevitable part of aging

For 25 years, scientists at Northwestern Medicine have been studying individuals aged 80 and older—dubbed “SuperAgers”—to better understand what makes them tick.

These unique individuals, who show outstanding memory performance at a level consistent with individuals who are at least three decades younger, challenge the long-held belief that is an inevitable part of aging.

Over the quarter-century of research, the scientists have seen some notable lifestyle and personality differences between SuperAgers and those aging typically—such as being social and gregarious—but “it’s really what we’ve found in their brains that’s been so earth-shattering for us,” said Dr. Sandra Weintraub, a professor of psychiatry and and neurology at Northwestern University Feinberg School of Medicine.

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