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Category: biotech/medical – Page 468

A new technique using deep brain stimulation tailored to each patient exceeded researchers’ expectations in treating the cognitive impairments from moderate to severe traumatic brain injury.

In 2001, Gina Arata was in her final semester of college, planning to apply to law school, when she suffered a traumatic brain injury in a car accident. The injury so compromised her ability to focus she struggled in a job sorting mail.

“I couldn’t remember anything,” said Arata, who lives in Modesto with her parents. “My left foot dropped, so I’d trip over things all the time. I was always in car accidents. And I had no filter — I’d get pissed off really easily.”

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So our experiences or how we handle those experiences may have an effect on the expression of genes in our body.

A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.

It’s already known that head injuries are common in young kids, especially from falling, and can be linked to mood disorders and social difficulties that emerge later in life. Adverse childhood experiences are also very common, and can raise risk for disease, mental illness and substance misuse in adulthood.

“But we don’t know how those two things can interact,” said senior study author Kathryn Lenz, associate professor of psychology at The Ohio State University. “We wanted to understand whether experiencing a traumatic brain injury in the context of early life stress circumstances could modulate the response to the brain injury. And using an animal model allows us to really get into the mechanisms through which these two things might be impacting brain development as it’s occurring.”

Continue reading “Stress Changes More Genes in the Mouse Brain Than a Head Injury” | >

Using lasers rather than scalpels and saws has many benefits in surgery. Yet they are only used in isolated cases. But that could be about to change: laser systems are getting smarter and better all the time, as a research team from the University of Basel demonstrates.

Even back in 1957, when Gordon Gould coined the term “” (short for “Light Amplification by Stimulated Emission of Radiation”), he was already imagining the possibilities for its use in medicine. Surgeons would be able to make precise incisions without even touching the patient.

Before that could happen, however, there were—and still are—many hurdles to overcome. Manually controlled light sources have been superseded by mechanical and computer-controlled systems to reduce injuries caused by clumsy handling. Switching from continuous beams to pulsed lasers, which turn themselves rapidly on and off, has reduced the heat they produce. Technical advances allowed lasers to enter the world of ophthalmology in the early 1990s. Since then, the technology has moved on in other areas of medicine, too, but only in relatively few applications has it replaced the scalpel and the bone saw.

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Scientists at the University of Illinois Urbana-Champaign have developed a portable, self-powered ultraviolet-C device called the Tribo-sanitizer that can inactivate two of the bacteria responsible for many foodborne illnesses and deaths.

The Tribo-sanitizer’s UVC lamp is powered using the —electricity that is generated when two dissimilar materials come into contact. In tests, the Tribo-sanitizer successfully inactivated two potentially deadly foodborne bacteria, Escherichia coli O157:H7, and Listeria monocytogenes, mainly by damaging their DNA, according to findings published in the journal Nano Energy.

The bacteria selected as testing targets are two of the most common causes of serious foodborne illness outbreaks in the U.S. Escherichia coli produces toxins that can cause severe abdominal cramps, fever, bloody diarrhea, and kidney failure, and Listeria monocytogenes can cause listeriosis, which has the highest rates of hospitalization and mortality of any foodborne illness.

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So if I heard this right, after 8 minutes or so, the effects are temporary and he indicates people would have to take this every couple of years.

Here Akshay talks about his interest in aging, how he met with Dr Katcher and formed Yuvan Research and their experiments with E5 and the results that they saw.
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Continue reading “Reducing Biological Age By 67% : The Origins Of E5” | >

Could a fecal transplant pill be the antidepressants of the future?

Depression is real, and it is complex. Most conditions that affect our brain chemistry are going to be complex, and there are no easy, simple answers. We can’t cure depression by just exercising more, eating better, or taking a short vacation to recharge (although there is some evidence that getting more money, especially to lift you out of poverty, helps relieve depressive symptoms).

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PARIS, Dec 5 (Reuters) — France raised the risk level of bird flu to ‘high’ from ‘moderate’ on Tuesday after new cases of the disease were detected, forcing poultry farms to keep birds indoors to stem the spread of the highly contagious virus.

The decision by the agriculture ministry was published in the Official Journal on Tuesday.

Avian influenza, commonly known as bird flu, has led to the culling of hundreds of millions birds worldwide in recent years.

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