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New discovery from the molecular machinery for depression and addiction

When nerve cells have to communicate with each other in our brains, it involves release of neurotransmitters acting as messengers at neural synapses. Here the released neurotransmitter is bound and registered by receptors at the surface of the receiving nerve cell. This will, in turn, trigger a signal which is sent on to other nerve cells. The circuits in the brain using the neurotransmitters noradrenaline, dopamine, GABA and serotonin are known to play an important role in mood, reward and mental well-being, and they also have a key role to in mental disorders such as addiction and depression.

See Also: Obesity is associated with brain’s neurotransmitters

After release of neurotransmitters between nerve cells, they must, however, be removed again to end the signal. This is done by a family of transport proteins which function as molecular vacuum cleaners in the cell membrane of the nerve cell where they pump the neurotransmitter back into the nerve cell for later reuse. This transport is of great importance to the signaling between the nerve cells, but happens relatively slowly. A collaborative project between researchers from Aarhus University has made it possible to explain what happens in the crucial rate-limiting step in the transport process for neurotransmitters such as serotonin, noradrenaline, GABA and dopamine which are all transported by related proteins with the same mechanism.

31 responses to “Neverending Sex”

Let’s formulate the task of life extension slightly differently. Something like this…How can we extend sex appeal?

Gyms and beauty salons are in charge of this question now. There is some success, but it’s mostly superficial. Plastic surgery only masks, but doesn’t delay the processes of aging.

Expanding sex appeal is a complex task. Its aspects include both beauty and the activity of the brain. To be sexually attractive we have to be smart and fun. One cannot solve the problem of dementia with makeup.

We have to be in an excellent physical shape to be sexually attractive, but also things should be running smoothly with our hormonal regulation.

The task of extending the period of sex appeal is extremely science-intensive. It is not only the Viagra, but a complex impact on the whole organism. It is obvious that molecular biology is responsible for sex in the modern world.

Corrected: U.S. sees first case of bacteria resistant to last-resort antibiotic

By ransdell pierson and bill berkrot.

(Reuters) — U.S. health officials on Thursday reported the first case in the country of a patient with an infection resistant to a last-resort antibiotic, and expressed grave concern that the superbug could pose serious danger for routine infections if it spreads.

“We risk being in a post-antibiotic world,” said Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention, referring to the urinary tract infection of a 49-year-old Pennsylvania woman who had not traveled within the prior five months.

The Future of Humanity’s Food Supply Is in the Hands of AI

Perhaps it’s serendipitous, then, that the machines have finally arrived. Truly smart, truly impressive robots and machine learning algorithms that may help usher in a new Green Revolution to keep humans fed on an increasingly mercurial planet. Think satellites that automatically detect drought patterns, tractors that eyeball plants and kill the sick ones, and an AI-powered smartphone app that can tell a farmer what disease has crippled their crop.

Forget scarecrows. The future of agriculture is in the hands of the machines.

A Digital Green Thumb

Deep learning is a powerful method of computing in which programmers don’t explicitly tell a computer what to do, but instead train it to recognize certain patterns. You could feed a computer photos of diseased and healthy plant leaves, labeled as such. From these it will learn what diseased and healthy leaves look like, and determine the health of new leaves on its own.

AI ‘doctors’ will diagnose your X-rays

An Israeli medical imaging company has signed a deal with a Utah-based healthcare provider that could change the way we diagnose certain conditions. Zebra Medical Imaging is teaming up with Intermountain to work on a neural network that will compare fresh X-rays with the “millions” stored in its own database. The eventual aim of the project is to offer up suggestions to radiographers and other medical professionals and eliminate costly misdiagnoses.

For instance, let’s imagine that you’ve gone to hospital for some unknown condition and you get an X-ray. Rather than handing the slide to a doctor, who could miss a small shadow or other minor clue, the image would be handed to the computer. It would use deep learning to trawl an anonymized patient database looking for any anomalies that you might be suffering from. The current system will work on bone health, cardiovascular analysis and lung conditions, although who knows where the possibilities will end.

As deep learning technology gets more powerful, smaller and significantly cheaper, the potential for AI to assist doctors becomes more realistic. IBM has spent the last few years pushing Watson, its homegrown supercomputer, as a system to aid decision making for patients. At the same time, companies like LG are trying to shrink medical imaging technology to end the days of bulky hospital equipment being available for a chosen few. All in all, the idea of a medical tricorder is going from fantastical to plausible in less time than you’d expect.

Triggering the protein that programs cancer cells to kill themselves

WEHI | Apoptosis

Researchers at the Walter and Eliza Hall Institute in Australia have discovered a new way to trigger cell death that could lead to drugs to treat cancer and autoimmune disease.

Programmed cell death (a.k.a. apoptosis) is a natural process that removes unwanted cells from the body. Failure of apoptosis can allow cancer cells to grow unchecked or immune cells to inappropriately attack the body.

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