Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2781

ASCB’s Celldance Studios released Monday (Dec. 14) three new short videos made by cell scientists, featuring dramatic live cell imaging.

The videos, which take advantage of accelerating advances in super-resolution imaging, fluorescent tagging, and Big Data manipulation, where made in the labs of Douglas Robinson at John Hopkins University, John Condeelis at Albert Einstein College of Medicine, and Satyajit Mayor at the National Centre for the Biological Sciences (NCBS) in India.

The videos were announced at the 2015 American Society for Cell Biology annual meeting.

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Robot doctors, virtual reality vacations and smart toothbrushes. These are just a few of the things the world can expect to see in the not-so-distant future, says Stanford and Duke researcher and lecturer Vivek Wadhwa.

Speaking to a crowd of more than 300 people in Palm Beach in December at billionaire Jeff Greene’s “Closing the Gap” conference, which addressed the growing divide between the wealthy and poor and how the rise of machines might kill white-collar jobs, Wadhwa sketched a sci-fi vision for the future that he says will soon be a reality thanks to rapid technological innovation.

“The future is going to be happening much, much faster than anyone ever imagined,” said Wadhwa, explaining that tech growth has been exponential — meaning as technology advances it does so with increasing speed.

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Google’s verily Launches New Robotic Surgical Company called Verb Surgical by teaming up with Johnson & Johnson.

The company formerly known as Google Life Sciences is one of the firms behind Verb Surgical Inc, which will develop advanced surgical robots. This promises to be just the first of Verily’s medical and academic partnerships.

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Last week the FDA announced that they have granted permission for the TAME trial. The Targeting Aging with Metformin (TAME) trial is the first human trial specifically looking at an anti-aging drug in humans.

Repurposing An Old Medicine

Metformin is an old drug, first approved in France in 1957, for the treatment of type 2 diabetes and polycystic ovary syndrome (PCOS). However extracts from the French liliac (Galega officinalis), the plant containing a precursor of metformin, has been used to treat frequent urination, a symptom of diabetes, since the Middle Ages. In 2012 in the US about 60 million prescriptions for metformin were written, making metformin the most used antidiabetic drug. Amazingly, every year about 37,000 metric tons of metformin are produced! Metformin is also a super-cheap drug, costing only cents per dose.

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C. elegans roundworm (credit: The Goldstein Lab)

When researchers at The Scripps Research Institute (TSRI) in California administered an antidepressant called mianserin to the Caenorhabditis elegans roundworm in 2007, they discovered the drug increased the lifespan of the “young adulthood” of roundworms by 30–40 per cent.

So, does that mean it will work in humans? Not necessarily. “There are millions of years of evolution between worms and humans,” says TSRI researcher Michael Petrascheck. “We may have done this in worms, but we don’t want people to get the impression they can take the drug we used in our study to extend their own teens or early twenties.”

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This article is based on my skype conversation with Elizabeth Parrish, founder and CEO of BioViva. BioViva is a biotech company in the Seattle area focused on developing gene therapies to mitigate the diseases of aging. Liz is currently experimenting these therapies on herself. Her research was recently covered in a MIT Technology Review article and she did an AMA on Reddit you may want to check out.

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