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Stem cells, human trials, regenerative medicine, yay!


UNSW researchers say the therapy has enormous potential for treating spinal disc injury and joint and muscle degeneration and could also speed up recovery following complex surgeries where bones and joints need to integrate with the body (credit: UNSW TV)

A stem cell therapy system capable of regenerating any human tissue damaged by injury, disease, or aging could be available within a few years, say University of New South Wales (UNSW Australia) researchers.

Their new repair system, similar to the method used by salamanders to regenerate limbs, could be used to repair everything from spinal discs to bone fractures, and could transform current treatment approaches to regenerative medicine.

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Researchers have developed a new and highly efficient method for gene transfer. The technique, which involves culturing and transfecting cells with genetic material on an array of carbon nanotubes, appears to overcome the limitations of other gene editing technologies.

The device, which is described in a study published today in the journal Small, is the product of a collaboration between researchers at the University of Rochester Medical Center (URMC) and the Rochester Institute of Technology (RIT).

“This platform holds the potential to make the process more robust and decrease toxic effects, while increasing amount and diversity of genetic cargo we can deliver into ,” said Ian Dickerson, Ph.D., an associate professor in the Department of Neuroscience at the URMC and co-author of the paper.

HUGE deal for wearables and biomed technologies.


Researchers from the University of Illinois at Urbana-Champaign have demonstrated a new approach to modifying the light absorption and stretchability of atomically thin two-dimensional (2D) materials by surface topographic engineering using only mechanical strain. The highly flexible system has future potential for wearable technology and integrated biomedical optical sensing technology when combined with flexible light-emitting diodes.

“Increasing graphene’s low light absorption in visible range is an important prerequisite for its broad potential applications in photonics and sensing,” explained SungWoo Nam, an assistant professor of mechanical science and engineering at Illinois. “This is the very first stretchable photodetector based exclusively on graphene with strain-tunable photoresponsivity and wavelength selectivity.”

Graphene—an atomically thin layer of hexagonally bonded carbon atoms—has been extensively investigated in advanced photodetectors for its broadband absorption, high carrier mobility, and mechanical flexibility. Due to graphene’s low optical absorptivity, graphene photodetector research so far has focused on hybrid systems to increase photoabsorption. However, such hybrid systems require a complicated integration process, and lead to reduced carrier mobility due to the heterogeneous interfaces.

What if prospective parents had the opportunity to make decisions ahead of time about the combination of genetic traits their child would inherit? The question is more than science fiction, says Hank Greely, a law professor at Stanford University.

The underlying science and technology are advancing rapidly—and now is the time to consider carefully “what kind of legal changes would be necessary to try to maximize the benefits and minimize the harm of this new approach to making babies,” he says.

Greely explored the legal, ethical, and societal implications of emerging biotechnologies for a new book, The End of Sex and The Future of Human Reproduction (Harvard University Press, 2016), that envisions a world where procreation may not start in bedrooms, but rather in a petri dish in a medical clinic.

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Like this article highlights; we will see a day soon when all techies will need some level of bio-science and/ or medical background especially as we move closer to Singularity which is what we have seen predicted by Ray Kurzweil and others. In the coming decade/s we will no longer see tech credentials relying strictly on math/ algorithms, code, etc, Techies will need some deeper knowledge around the natural sciences.


If you are majoring in biology right now, I say to you: that was a good call. The mounting evidence suggests that you placed your bet on the right degree. With emergent genetic recombination technologies improving at breakneck speed alongside a much deepened understanding of biological circuitry in simple, “home grown” metabolic systems, this field is shaping up to be a tinkerer’s paradise.

Many compare this stage of synthetic biology to the early days of microprocessing (the precursor to computers) when Silicon Valley was a place for young entrepreneurs to go if they needed a cheap place to begin their research or tech business. One such tech entrepreneur, the founder of O’Reilly media, Tim O’Reilly — who also coined the term “open source” — made this comparison in an interview with Wired magazine., O’Reilly further commented on synthetic biology saying, “It’s still in the fun stage.”

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BUFFALO, N.Y. (WIVB) – The number of people being diagnosed with diabetes is growing. Every third American adult will develop type 2 diabetes within the next 35 years. But there may be a new way to manage the illness.

A new device might make managing your insulin levels or even treating allergies virtually painless. We know Western New York is becoming a hub for nano-medicine. Now a local organization is on the front lines of whats called nano- patch technology.

At the New York Center for Nanomedicine Research in downtown Buffalo, the team is working on patch technology. A similar kind of patch may soon be on the market. It uses nano- technology micro-needles to transmit medication and test blood sugar levels through the device is so small, you don’t even feel them. Scottpatrick Sellitto was part of the original team which developed nano-patch technology. He and his team say this “personalized” treatment is what’s next in the medical field. Selitto said, “It’s very precise, and it’s tailored literally just for you and that is the next frontier of medicine.”

Stuart Russell received his B.A. with first-class honours in physics from Oxford University in 1982 and his Ph.D. in computer science from Stanford in 1986. He then joined the faculty of the University of California at Berkeley, where he is Professor (and formerly Chair) of Electrical Engineering and Computer Sciences and holder of the Smith-Zadeh Chair in Engineering. He is also an Adjunct Professor of Neurological Surgery at UC San Francisco and Vice-Chair of the World Economic Forum’s Council on AI and Robotics. He has published over 150 papers on a wide range of topics in artificial intelligence including machine learning, probabilistic reasoning, knowledge representation, planning, real-time decision making, multitarget tracking, computer vision, computational physiology, and global seismic monitoring. His books include “The Use of Knowledge in Analogy and Induction”, “Do the Right Thing: Studies in Limited Rationality” (with Eric Wefald), and “Artificial Intelligence: A Modern Approach” (with Peter Norvig).

Abstract:

Autonomous weapons systems select and engage targets without human intervention; they become lethal when those targets include humans. LAWS might include, for example, armed quadcopters that can search for and eliminate enemy combatants in a city, but do not include cruise missiles or remotely piloted drones for which humans make all targeting decisions. The artificial intelligence (AI) and robotics communities face an important ethical decision: whether to support or oppose the development of lethal autonomous weapons systems (LAWS).

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