CU Cancer Center member, Michelle Springer, MS, CGC, presents “Genetic Testing for Family Members” at the Hereditary Cancer Conference.
Keynote lecture at Neuroinformatics 2016 in Reading, United Kingdom.
TRACK I — NORMAL DEVELOPMENT / COGNITION
Talk title: Typical and atypical development of large-scale brain networks.
Speaker: Vinod Menon, Stanford School of Medicine, USA
About INCF
The International Neuroinformatics Coordinating Facility (INCF) is an international non-profit organization devoted to advancing the field of neuroinformatics and global collaborative brain research. Learn more about INCF: www.incf.org
Nervous systems are complex networks, comprised of billions of neurons connected by trillions of synapses. These connections are subject to specific wiring rules that are thought to result from competitive selection pressures to minimise wiring costs and promote complex, adaptive function. While most connections in the brain are short-range, a smaller subset of metabolically costly projections extend over long distances to connect disparate anatomical areas. These long-range connections support integrated brain function and are concentrated between the most highly connected network elements; the hubs of the brain. Hub connectivity thus plays a vital role in determining how a given nervous system negotiates the trade-off between cost and value, and natural.
selection may favour connections that provide high functional benefit for low cost.
Consistent with this view, Professor Alex Fornito will present evidence.
that hub connectivity is under strong genetic control. He will show that the strength of connectivity between hubs in the human brain is more heritable than connectivity between other nodes, and that the genetic variants influencing hub connectivity overlaps with those implicated in mental illness and intelligence. He will also discuss the progress and challenges of developing generative models that evaluate the role of different cost-value trade-offs in driving complex brain topology.
Continue reading “Brain network hubs: maps, molecules, and models” »
“The Vibrating Glove Can Control Parkinson’s Symptoms.”
This session will discuss the exciting new vibrating glove that he has developed to alleviate tremor, stiffness, abnormal walking, slow body movement and balance problems associated with Parkinson’s Disease and other movement disorders. Hear from Dr. Tass on the vibrating glove and how it can improve your symptoms and quality of life.
This video discusses how monoclonal antibodies may be valuable tools against the growing threat of antimicrobial-resistant bacteria, explores their bacteria-killing mechanisms, and highlights their potential as adjuvant therapies to antibiotics.
Link to script and all references:
https://docs.google.com/document/d/1jxjCI51yXLPjsEyBD6KsO6X4…sp=sharing.
Production Director: Neil Lin.
Video Editor: Neil Lin.
Scriptwriter: Neil Lin.
Narration & Script Editing: Nishaad Sheth.
With Audio & Graphics Help From: James Wang & David Klitovchenko
“DT-MRI captures these abnormal connections that lead to the symptoms that children with autism often have, such as impaired social communication and repetitive behaviors.”
When it comes to autism, early diagnosis is key for effective intervention and support.
When it comes to autism, early diagnosis is key for effective intervention and support. Now, a newly created artificial intelligence (AI) system has been found to have the ability to diagnose children with autism between the ages of 24 and 48 months with a rate of 98.5 percent accuracy.
Continue reading “AI system uses MRI to diagnose autism in children as young as 24 months” »
In a bid to combat the ongoing homelessness crisis, Los Angeles County is using artificial intelligence (AI) to identify and support individuals at the highest risk of becoming homeless.
This pioneering pilot program analyzes data from seven county agencies, including medical visits, mental health care, substance abuse diagnoses, arrests, and public benefit sign-ups, to identify those most vulnerable to homelessness.
Dedicated case managers then reach out to these individuals, offering comprehensive support for four to six months, including access to $4,000 to $6,000 in aid to cover essential expenses like rent, utilities, and groceries. This assistance is designed to stabilize not only their housing but also their overall well-being.
The technique represents an important step in engineering skin grafts, drug testing. A team led by scientists at Rensselaer Polytechnic Institute has 3D-printed hair follicles in human skin tissue cultured in the lab. This marks the first time researchers have used the technology to generate hair follicles, which play an important role in skin healing and function.
The finding, published in the journal Science Advances, has potential applications in regenerative medicine and drug testing, though engineering skin grafts that grow hair are still several years away.
“Our work is a proof-of-concept that hair follicle structures can be created in a highly precise, reproducible way using 3D-bioprinting. This kind of automated process is needed to make future biomanufacturing of skin possible,” said Pankaj Karande, Ph.D., an associate professor of chemical and biological engineering and a member of Rensselaer’s Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies, who led the study.
An AI tool that can predict 10-year risk of deadly heart attacks, could transform treatment for patients who undergo CT scans to investigate chest pain, according to British Heart Foundation-funded research presented today at the American Heart Association’s Scientific Sessions in Philadelphia.
In the first real-world trial of the AI tool, it was found to improve treatment for up to 45 per cent of patients. The AI technology could potentially save the lives of thousands with chest pain, who may not have been identified as at risk of a heart attack, and therefore may not have received appropriate treatment to lower their risk. With the technology also found to be cost-effective, the researchers hope it could change the management of patients who are referred for chest pain investigations, across the NHS.
Every year in the UK around 350,000 people have a cardiac CT scan – the standard test to identify any narrowings or blockages in the coronary arteries. In around three quarters of cases, there is no clear sign of significant narrowings, so patients are often reassured and discharged. Unfortunately, many of these people will die from a heart attack in future, because small, undetectable narrowings may break up if they are inflamed, blocking the arteries. Until recently, it was not possible to identify these patients at risk.
Polyphosphoesters, molecules containing phosphorus as the central element, are easily traceable without the need for contrast agents, thanks to developments by researchers from the University of Twente (UT). Normally, these molecules display a similar molecular composition to our DNA, leading to considerable “noise” in the image.
The UT researchers provided a solution and developed unique polymers that are traceable with magnetic resonance imaging (MRI). Dr. Olga Koshkina, Project Leader in the Sustainable Polymer Chemistry Group, published this new concept of traceable polymers in Communications Chemistry.
The researchers adjusted the properties of polyphosphoesters (special polymers with a molecular structure inspired by DNA and RNA). As a result, the polymers acquired a different “MRI color,” making them more distinguishable from the natural background. Additionally, they exhibit other physical MRI characteristics suitable for imaging.
