The mechanisms underlying human cell diversity are unclear. Here the authors provide a single-cell epigenome map of human neural organoid development and dissect how epigenetic changes control cell fate specification from pluripotency to distinct cerebral and retina neural types.
Japanese researchers have developed a novel technique to attach engineered skin tissue to humanoid robots.
Robotic platforms may benefit from enhanced mobility, embedded sensing capabilities, self-healing capabilities, and a more realistic appearance.
The innovation was made possible by mimicking skin-ligament structures and using V-shaped perforations in a robot face.
The organoids were treated with zinc oxide nanoparticles (ZnO NPs), which are a liver toxic material, and nontoxic gold nanoparticles (AuNPs). The comparison showed that the toxicity of each material could be accurately observed, in contrast to the conventional method.
Ahruem Baek, a senior researcher at KRISS, said, “Based on our results, we will establish standard nanomaterial and nanomedicine safety assessment procedures using organoids, contributing to the advancement of Korea’s nano-industry.”
The results from this study may allow for rapid and accurate safety assessment of nanomaterials and nanomedicine using organoids, contributing to the safe utilization of nanomaterials in various strategic technical fields.
Soft bioelectronic devices are made from polymer-based and hybrid electronic materials that form natural interfaces with the human body. In this Review, the authors present recent developments in soft bioelectronic sensors and actuators, and discuss system-level integration for wearable and implantable medical applications.
The integration of artificial neuromorphic devices with biological systems plays a fundamental role for future brain-machine interfaces, prosthetics, and intelligent soft robotics. Harikesh et al. demonstrate all-printed organic electrochemical neurons on Venus flytrap that is controlled to open and close.
Proteins are the building blocks of life, involved in virtually every biological process. Understanding how proteins interact with each other is crucial for deciphering the complexities of cellular functions, and has significant implications for drug development and the treatment of diseases.
Many people are familiar with oncogenes—genes long known to be involved in cancers in humans, such as the gene Src. What’s less widely understood is that oncogenes didn’t evolve just to cause cancer in species, but rather to control events of normal growth and differentiation.
To help myself and others keep track of the fast-paced world of biotech, I have put together this list of 107 companies and notable research nonprofits! I wrote down some important facts about each entry as well as included links to their websites.
PDF version: List of Biotechnology Companies to Watch – by Logan Thrasher Collins
I created this list of organizations (107 total to date) to serve as a resource to help people learn about and keep track of key biotechnology companies. Some of these are emerging startups, some are established giants, and some provide useful services. Some notable nonprofit organizations are included as well. Though this list is far from comprehensive, I have tried to cover as many of the key players as possible. It is also important to realize that this landscape is constantly changing, so some of the information on this list will eventually transition into antiquity. The list was originally started over the course of 2021, updated during the summer of 2022, and updated again during the summer of 2024. I hope you enjoy delving into the exciting world of biotechnology!
A UK teenager with severe epilepsy has become the first person in the world to be fitted with a brain implant aimed at bringing seizures under control.
Oran Knowlson’s neurostimulator sits under the skull and sends electrical signals deep into the brain, reducing his daytime seizures by 80%.
His…
His mother, Justine, said that her son had been happier, chattier and had a much better quality of life since receiving the device. “The future looks hopeful, which I wouldn’t have dreamed of saying six months ago,” she said.
Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer’s and similar diseases, before extensive brain cell death and dementia set in. A study published in Alzheimer’s & Dementia shows up to a six-month window in which disease progress could be tracked and treatments tested in rhesus macaques.