Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,605

There is an urgent need to develop better biomarkers and to use the in cost effective packages for accurate measurement of aging.

As human life expectancy has increased throughout the 20th and 21st centuries this has led to a steady increase in the population of older people. With that increase has come the rise of age-related diseases and disabilities. As a result it is becoming ever more important to develop preventative strategies to monitor and maintain health as well as therapies that directly address the various aging processes to delay or prevent the onset of age-related diseases.

One of the ways we can do this is by developing more effective ways to measure how someone is aging, this means developing high quality aging biomarkers. The challenge in creating such biomarkers has always been the fundamental question – what do we measure?

Chronological age is a poor indication of how someone might be aging and is not a good way to ascertain an individual’s risk factor for various age-related diseases. This is simply because everyone ages differently and at different rates. Whilst everyone ages due to the same processes the speed at which these different processes occur can vary between individuals.

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By Kim Thurler, Tufts University

(MEDFORD/SOMERVILLE, Mass.) — Changing the natural electrical signaling that exists in cells outside the nervous system can improve resistance to life-threatening bacterial infections, according to new research from Tufts University biologists. The researchers found that administering drugs, including those already used in humans for other purposes, to make the cell interior more negatively charged strengthens tadpoles’ innate immune response to E. coli infection and injury. This reveals a novel aspect of the immune system – regulation by non-neural bioelectricity – and suggests a new approach for clinical applications in human medicine. The study is published online May 26, 2017, in npj Regenerative Medicine, a Nature Research journal.

“All cells, not just nerve cells, naturally generate and receive electrical signals. Being able to regulate such non-neural bioelectricity with the many ion channel and neurotransmitter drugs that are already human-approved gives us an amazing new toolkit to augment the immune system’s ability to resist infections,” said the paper’s corresponding author Michael Levin, Ph.D., Vannevar Bush Professor of Biology and Director of the Allen Discovery Center at Tufts and the Tufts Center for Regenerative and Developmental Biology in the School of Arts and Sciences. Levin is also an Associate Faculty member of the Wyss Institute of Biologically Inspired Engineering at Harvard University.

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  • With Chinese scientists announcing that they have tested CRISPR on a human for the first time, the U.S. must decide soon whether it will be a leader or a follower in advancing the tech.
  • While gene editing technology could be used in nefarious ways, it could also cure diseases and improve millions of lives, but we won’t know how effective it is until we begin human trials.

While the middle part of the 20th century saw the world’s superpowers racing to explore space, the first global competition of this century is being set in a much smaller arena: our DNA.

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As well as beating us at board games, driving cars, and spotting cancer, artificial intelligence is now generating brand new sounds that have never been heard before, thanks to some advanced maths combined with samples from real instruments.

Before long, you might hear some of these fresh sounds pumping out of your radio, as the researchers responsible say they’re hoping to give musicians an almost limitless new range of computer-generated instruments to work with.

The new system is called NSynth, and it’s been developed by an engineering team called Google Magenta, a small part of Google’s larger push into artificial intelligence.

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