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Removing Senescent Cells Improves Heart Health

Researchers at Newcastle University have shown that clearing out senescent cardiac muscle cells from the hearts of aged mice restores heart health.

It seems that not a month goes by without a new study showing that senolytics, drugs that remove aged and damaged cells from the body, improve organ or tissue function by reversing some aspects of aging. A new study has shown that removing senescent cells from the hearts of old mice restores heart health and alleviates the detrimental effects of cardiac aging, including myocardial hypertrophy and fibrosis.

Scientist finds cure for HPV infection, cervical cancer after 20 years of trying

This HPV cure comes at a time when cervical cancer cases are quickly becoming the leading cause for death among female cancer patients around the world, the World Health Organisation (WHO) said in a statement.

The researchers specialise in early detection and photodynamic therapy to fight HPV and have succeeded in winning the ultimate battle — a 100 percent cure — after twenty years of tweaking the treatment.

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Converting cells into new neurons could lead to a pill that repairs brain damage

As powerful as the human brain is, once it’s damaged it can’t really recover completely. Now researchers at Penn State may have found a way to boost the brain’s regenerative abilities, using certain molecules to convert neighboring cells into new neurons. The technique could eventually lead to pills that treat brain injuries, stroke or Alzheimer’s disease.

Giving Coral Reefs a Second Chance with Probiotics

While testing of the probiotic supplements is currently confined to the lab, Peixoto envisions the treatment being administered on wild reefs. The probiotics could be sprayed from a plane, similar to how pesticides are spread over fields, or dropped like little bacterial bombs to target areas more specifically. Peixoto acknowledges the risk of trying to deliberately manipulate microbial ecosystems in the oceans, but believes the probiotics could be a viable long-term solution to coral reefs’ declining health.


When faced with high heat and disease, coral treated with microbial supplements fared better.

Advances in cryoablation for pancreatic cancer

Extreme cold can be our friend in other ways too!! Directed attacks on liver cancer and pancreatic cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716077/


Pancreatic carcinoma is a common cancer of the digestive system with a poor prognosis. It is characterized by insidious onset, rapid progression, a high degree of malignancy and early metastasis. At present, radical surgery is considered the only curative option for treatment, however, the majority of patients with pancreatic cancer are diagnosed too late to undergo surgery. The sensitivity of pancreatic cancer to chemotherapy or radiotherapy is also poor. As a result, there is no standard treatment for patients with advanced pancreatic cancer. Cryoablation is generally considered to be an effective palliative treatment for pancreatic cancer. It has the advantages of minimal invasion and improved targeting, and is potentially safe with less pain to the patients. It is especially suitable in patients with unresectable pancreatic cancer. However, our initial findings suggest that cryotherapy combined with 125-iodine seed implantation, immunotherapy or various other treatments for advanced pancreatic cancer can improve survival in patients with unresectable or metastatic pancreatic cancer. Although these findings require further in-depth study, the initial results are encouraging. This paper reviews the safety and efficacy of cryoablation, including combined approaches, in the treatment of pancreatic cancer.

Keywords: Pancreatic cancer, Cryoablation, Combination therapy, Cryoimmunotherapy.

Core tip: Pancreatic carcinoma is a devastating cancer of the digestive system. The majority of patients present too late to undergo radical surgery and there is no standard treatment for patients with advanced pancreatic cancer. Cryoablation is considered a palliative therapy in the treatment of pancreatic cancer; however, our results suggest that cryoablation may be an effective and safe treatment that can improve survival and quality of life in patients with unresectable or metastatic pancreatic cancer, particularly in combination with other modalities such as 125-iodine seed implantation and immunotherapy. As such, cryoablation may be a potential standard treatment for pancreatic cancer.

Red-eyed mosquitoes engineered to break the chain of Zika virus transmission

Scientists in Australia are looking at some pretty creative ways to tackle the Zika virus, which continues to pose a risk to millions across Africa, Asia and parts of the Americas. Following a trial last year where researchers were able to decimate disease-spreading mosquitos in the country’s north, scientists have now demonstrated an engineering technique that renders the biggest transmitter of the virus largely immune to it, raising hopes of a new way to control the spread of Zika and other mosquito-borne diseases.

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