F ifteen-minute workouts could reverse diabetes in just six weeks, new research suggests. A trial of overweight men found that short, intense resistance training sessions three times a week significantly boosted their ability to manage insulin.

Previous research has indicated that 45-minute workouts could have this effect, but the new study has been greeted with particular excitement as experts believe type 2 diabetes patients will be more likely to commit to shorter sessions.

It is estimated that by 2025 there will be five million people with a diabetes diagnosis in the UK, 90 per cent of whom will have type 2, which is related to lifestyle.

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

Purdue University researchers are developing a series of drug compounds that have shown promise in treating such cases. About 30 percent of AML patients have a mutation caused by a kinase called FLT3, which makes the leukemia more aggressive. Inhibitors of FLT3, such as Radapt, approved last year by the U.S. Food and Drug Administration, have shown good initial response to treating leukemia. Gilteritinib, another FLT3 inhibitor, was recently approved toward the end of 2018. But AML patients on FLT3 inhibitor therapy often relapse because of secondary mutations in the FLT3 and existing treatments have not been fully successful in treating those cases.

Researchers on a team led by Herman O. Sintim, the Drug Discovery Professor of Chemistry in Purdue’s Department of Chemistry, say they have developed a series of compounds that work not only on AML with common FLT3 mutation, but also drug-resistant AML harboring problematic mutations, such as the gatekeeper F691L mutation, which some leukemia patients who relapse harbor.