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Category: biotech/medical – Page 2,489

AI Course with Sebastian Thrun and Peter Norvig: Udacity Course

Artificial Intelligence (AI) is a field that has a long history but is still constantly and actively growing and changing. Artificial Intelligence (AI) technology is increasingly prevalent in our everyday lives. It has uses in a variety of industries from gaming, journalism/media, to finance, as well as in the state-of-the-art research fields from robotics, medical diagnosis, and quantum science.


Udacity was born out of a Stanford University experiment in which Sebastian Thrun and Peter Norvig offered their “Introduction to Artificial Intelligence” course online to anyone, for free. Over 160,000 students in more than 190 countries enrolled and not much later, Udacity was born.

Udacity, a pioneer in online education, is building “University by Silicon Valley”, a new type of online university that: – teaches the actual programming skills that industry employers need today; – delivers credentials endorsed by employers, because they built them; – provides education at a fraction of the cost and time of traditional schools.

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How Two Paralyzed Patients Walked Again Without Surgery

The protocol, dubbed Walk Again Neuro-Rehabilitation (WA-NR), first uses EEG to record and control virtual avatars and robotic exoskeleton walkers while the patient wears a “tactile shirt” that offers them sensory feedback. This stimulation theoretically teaches damaged nerves to reroute their motor functions to healthy ones. Following the program for just three years, the patients—some paralyzed for decades—dramatically regained sensation in their lower limbs. They could feel where their legs were in space and better control their lower limbs. Some even reported feelings of normal, welcomed pain after a sharp jab.

The current study, published in Scientific Reports, takes neurorehab a step further. In two patients from the original cohort, the team further trained and examined their neuro-recovery in detail. Patient P1 was a middle-aged man paralyzed for 4.5 years at the onset of the study; P2, a 32-year-old, had been paralyzed for a decade. Although trained with WA-NR, both patients scored on the low end of overall movement, with the ability to extend their knees at most.

For each training session, the patients wore an EEG cap to measure movement intent and had eight electrodes placed on the skin of each leg to stimulate muscles. Simultaneously they wore a haptic shirt, which gave them a sense of their body in space by stimulating their forearms.

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First-of-its-kind platform aims to rapidly advance prosthetics

A new open-source, artificially intelligent prosthetic leg designed by researchers at the University of Michigan and Shirley Ryan AbilityLab is now available to the scientific community.

The leg’s free-to-copy design and programming are intended to improve the quality of life of patients and accelerate by offering a unified platform to fragmented research efforts across the field of bionics.

“Our Open-Source Bionic Leg will enable investigators to efficiently solve challenges associated with controlling across a range of activities in the lab and out in the community,” said lead designer Elliott Rouse, core faculty at U-M’s Robotics Institute and assistant professor of mechanical engineering. “In addition, we hope our bionic leg will unite researchers with a common hardware platform and enable new investigators from related fields to develop innovative control strategies.”

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First-ever spider glue genes sequenced, paving way to next biomaterials breakthrough

UMBC postdoctoral fellow Sarah Stellwagen and co-author Rebecca Renberg at the Army Research Lab have published the first-ever complete sequences of two genes that allow spiders to produce glue—a sticky, modified version of spider silk that keeps a spider’s prey stuck in its web. The findings appeared in Genes, Genomes, Genetics.

The innovative method they employed could pave the way for others to sequence more silk and glue , which are challenging to sequence because of their length and repetitive structure. Better understanding of these genes could move scientists closer to the next big advance in biomaterials.

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Scientists identify gene that helps people live to a ripe old age

Researchers at Amsterdam’s UMC have identified a rare gene that halves people’s chances of developing dementia in old age.

People with the genetic variant, which occurs in around 1% of the population, are also more likely to live longer. The researchers studied 16 different sample populations in Europe and North America, including a number of people over the age of 100, for the study published in the journal Acta Neuropathologica.

The discovery could potentially be used to treat Alzheimer’s disease and other degenerative illnesses such as frontotemporal and Lewy body dementia.

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DARPA’s New Project Is Investing Millions in Brain-Machine Interface Tech

When Elon Musk and DARPA both hop aboard the cyborg hypetrain, you know brain-machine interfaces (BMIs) are about to achieve the impossible.

BMIs, already the stuff of science fiction, facilitate crosstalk between biological wetware with external computers, turning human users into literal cyborgs. Yet mind-controlled robotic arms, microelectrode “nerve patches”, or “memory Band-AIDS” are still purely experimental medical treatments for those with nervous system impairments.

With the Next-Generation Nonsurgical Neurotechnology (N3) program, DARPA is looking to expand BMIs to the military. This month, the project tapped six academic teams to engineer radically different BMIs to hook up machines to the brains of able-bodied soldiers. The goal is to ditch surgery altogether—while minimizing any biological interventions—to link up brain and machine.

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Supercharging adoptive T cell therapy to overcome solid tumor–induced immunosuppression

The development of new cancer immunotherapies including checkpoint blockade and chimeric antigen receptor (CAR) T cell therapy has revolutionized cancer treatment. CAR T cells have shown tremendous success in certain B cell malignancies, resulting in U.S. Food and Drug Administration (FDA) approval of this approach for certain types of leukemia and lymphoma. However, response rates against solid cancer have been less successful to date. Approaches to modulate the immunosuppressive tumor microenvironment including targeting checkpoint pathways, modulating metabolic pathways, and generating cytokine-producing T cells have led to considerable enhancement of adoptive T cell immunotherapy, first in preclinical models and now in patients.

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