http://www.undoing-aging.org/news/professor-richard-barker-t…nbrFm8JTxA
Richard is an internationally respected leader in healthcare and life sciences. He says: “I’m focused on accelerating precision medicine technologies to advance our healthy lifespan”.
Stem cell research firm Celprogen Inc. has been working on something quite exciting for some time now, which has remained largely under the radar until very recently. The California-based company announced it has successfully 3D printed a human brain organelle using brain stem cells. The bioprinted brain could have applications in studying neurological diseases.
More than just announcing the bioprinted brain organelle, Celprogen has also used the brain to study the “role of Microglia activation and deactivation in neurological diseases.” Through this research and experimentation, the company says it has identified and characterized 11 lead compounds that could be potential drug candidates for diseases such as Alzheimer’s, Parkinson’s and Glioblastoma.
Yesterday, we announced the successful completion of the NAD+ Mouse Project after a great fundraiser, but it seems we are not done yet. The research team at Harvard has announced a new stretch goal for the last two days of the campaign.
A new $75,000 goal is to be the final step, and to support that, Dr. David Sinclair is offering to fund match the next $5000 in donations to the project to help it reach this final goal. So, for the next two days, all donations are worth double.
The final goal will be to add even more comprehensive testing, such as end-of-life pathology (frequency and specificity of neoplasms/tumors/cancer) and MRI diagnostics (body composition, lean-to-fat ratio). This would really allow the researchers to maximize the useful data they collect during the study and help assess any changes to cancer risk, why each animal died, and what age-related diseases were affected by the drug.
New research shows how police could use forensic DNA to track down a suspect’s relatives in genealogy databases that store a different kind of genetic data—and that were never intended for use in police investigations.
In other words, if your sibling leaves DNA at a crime scene, it could lead detectives to your door. That suggests new investigative possibilities for police—and also new concerns about genetic privacy and whether authorities who use forensic DNA in creative ways might be overstepping their bounds, says Noah Rosenberg, a professor of biology at Stanford University and senior author of a study, which appears in Cell.
“The potential to link people’s genotypes across databases has been developing for some time. It is both of interest and concerning, depending on one’s point of view,” says Rosenberg, who is also a member of Stanford Bio-X.
Good information 💜.
Dr. Antonei Csoka of Howard University discusses the concept of aging as meta-disease and about the hierarchy of some of the Hallmarks of Aging. He also discusses some of the philosophical and metaphysical underpinnings for the goal of overcoming age-related disease.
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Scientists have found further evidence that the gut, or more specifically the appendix, might play a role in the development of Parkinson’s disease.
The international team of scientists reviewed two datasets, including a large registry from Sweden, and found that removal of the appendix was associated with a decreased risk of developing Parkinson’s disease. They also found that the human appendix contains clumps of a protein called alpha-synuclein in a form associated with the disease. There’s more work to be done, and the authors are not advocating that people preemptively remove their appendixes, but they hope that the research could provide a pathway towards treatment.
