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Saskatchewan Celebrates Science During Global Biotech Week with Online Events and Activities

From the Science of Beer to learning about the benefits of GMOs; Saskatchewan is celebrating science with exciting online events and activities that showcase the province’s bioscience sector. Ag-West Bio, Saskatchewan’s bioscience industry association, coordinates events with the help of a local committee.

Ag-West Bio President and CEO Karen Churchill says amid the COVID-19 pandemic, biotechnology is in the spotlight. “Saskatchewan organizations in our research cluster have joined the global effort to develop vaccines as well as preventative and treatment solutions to deal with the virus. As a community, we should take note of the achievements of our local scientists and companies. Global Biotech Week gives us an opportunity to give them a (virtual) pat on the back!”

The Government of Saskatchewan and the Cities of Regina and Saskatoon have proclaimed September 28 to October 4 as Global Biotech Week.

Data Science to Accelerate Drug Discovery with Artificial Intelligence and Machine Learning, Says Frost & Sullivan

Frost & Sullivan’s recent analysis, Data Science Impacting the Pharmaceutical Industry, finds that data science tools are promising technologies transforming drug discovery costs, speed, and efficiency. When combined with other emerging tech areas, artificial intelligence (AI) technologies move…


Pharmaceutical companies and hospitals are adopting data science rapidly, and its application is going to be established in all branches of healthcare

SANTA CLARA, Calif., Sept. 29, 2020 /PRNewswire/ — Frost & Sullivan’s recent analysis, Data Science Impacting the Pharmaceutical Industry, finds that data science tools are promising technologies transforming drug discovery costs, speed, and efficiency. When combined with other emerging tech areas, artificial intelligence (AI) technologies move to the next phase of advancements. Hence, they are expected to witness adoption by pharma and biotech companies in the next four to five years. Further, with the COVID-19 pandemic, AI and machine learning (ML) can be used for drug research and clinical trials against the coronavirus to screen large databases and perform docking studies to identify existing potential drugs or design new drugs using advanced learning algorithms.

For further information on this analysis, please visit: http://frost.ly/4l2.

“Applying data science tools in healthcare, especially for drug discovery, has a huge potential to systematically change the entire existing practices and methods,” said Aarthi Janakiraman, Technical Insights Research Manager at Frost & Sullivan. “Additionally, pharmaceutical companies and hospitals are adopting this system rapidly, and its application is going to be established in all branches of healthcare.”

Tone of voice matters in neuronal communication

WOODS HOLE, Mass. — The dialogue between neurons is of critical importance for all nervous system activities, from breathing to sensing, thinking to running. Yet neuronal communication is so fast, and at such a small scale, that it is exceedingly difficult to explain precisely how it occurs. A preliminary observation in the Neurobiology course at the Marine Biological Laboratory (MBL), enabled by a custom imaging system, has led to a clear understanding of how neurons communicate with each other by modulating the “tone” of their signal, which previously had eluded the field. The report, led by Grant F. Kusick and Shigeki Watanabe of Johns Hopkins University School of Medicine, is published this week in Nature Neuroscience.

In 2016 Watanabe, then on the Neurobiology course faculty, introduced students to the debate over how many synaptic vesicles can fuse in response to one action potential (see this 2-minute video for a quick brush-up on neurotransmission). To probe this controversy, they used a “zap-and-freeze” imaging technology conceived by co-authors M. Wayne Davis, Watanabe and Erik Jorgensen, and built by Leica for testing in the Neurobiology course. They zapped a neuron with electricity to induce an action potential, then quickly froze the neuron and took an image. They saw multiple vesicles fusing at once at many synapses, the first novel finding of this Nature Neuroscience report.

But there was more. Back at Johns Hopkins, Kusick and Watanabe decided to walk through the neurotransmission process with zap-and-freeze, taking images every 3 milliseconds after the action potential. That’s when they found an answer to an even larger question — how do neurons change the tone of their neurotransmission signal?

Ransomware reportedly to blame for outage at US hospital chain

It doesn’t appear staff or patient information was compromised.


Health care provider Universal Health Services, one of the largest chains in the US, has been hit by an apparent ransomware attack, TechCrunch reported. UHS facilities in California, Florida, North Dakota, Arizona, and other locations began noticing problems early Sunday, with some locations reporting locked computers and phone systems.

Some UHS hospitals had to use pen and paper to file patient information as a result, according to NBC News.

The hospital system, which has more than 400 locations in the US and the UK, said in a statement on Monday that its IT network across several facilities was offline “due to an IT security issue.” No patient or employee data appears to have been compromised, according to the statement, which did not mention malware or ransomware.

Invention Using Terahertz Radiation Could Make Particle Accelerators 10 Times Smaller

SLAC invention uses terahertz radiation to power a miniscule copper accelerator structure.

Particle accelerators generate high-energy beams of electrons, protons and ions for a wide range of applications, including particle colliders that shed light on nature’s subatomic components, X-ray lasers that film atoms and molecules during chemical reactions and medical devices for treating cancer.

As a rule of thumb, the longer the accelerator, the more powerful it is. Now, a team led by scientists at the Department of Energy’s SLAC National Accelerator Laboratory has invented a new type of accelerator structure that delivers a 10 times larger energy gain over a given distance than conventional ones. This could make accelerators used for a given application 10 times shorter.

Multiple Unapproved Drugs Found in “Brain Boosting” Supplements

Researchers identified five unapproved drugs in dangerous combinations and doses in over-the-counter cognitive enhancement drugs. Side effects of the unapproved drugs include increases and decreases in blood pressure, agitation, and sedation.approved drugs in dangerous combinations and doses in over-the-counter cognitive enhancement drugs. Side effects of the unapproved drugs include increases and decreases in blood pressure, agitation, and sedation.approved drugs in dangerous combinations and doses in over-the-counter cognitive enhancement drugs. Side effects of the unapproved drugs include increases and decreases in blood pressure, agitation, and sedation.

Seismic sound waves crossing the deep ocean could be a new thermometer

It’s no problem atoll

To show that this works, the researchers used a seismometer station on Diego Garcia, a small atoll in the Indian Ocean about 3,000 kilometers from Sumatra. The tectonic plate boundary there is incredibly active, so there’s no shortage of earthquakes to work with. Between 2004 and 2016, there were over 4,000 earthquakes of magnitude 3.0 or higher that occurred near the Nias Island area of Sumatra. The researchers carefully processed all of these events to find repeaters similar enough to do the temperature calculation. They found over 2,000 such pairs based on 900 earthquakes.

If this portion of the Indian Ocean were to warm 1° C, T-waves from those earthquakes would take 5.4 seconds longer to reach this seismometer. The observed changes are smaller than that but they are coherent—there’s both an annual cycle and a gradual warming trend that look similar to other, more traditional datasets.

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