Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,321

Cancer is a disease that touches just about everyone. According to the American Cancer Society, men have a 39% chance of contracting some form of cancer at some point in their lives, while women have a slightly lower risk at 37%. And if you’re fortunate enough not be diagnosed with cancer yourself, the odds are high that someone you know will.

Because of this, a cure for cancer is the holy grail of the medical research community. Incredible treatments have been developed, but for hundreds of years, the hunt for an actual cure has felt like the hunt for a unicorn… a beautiful prize that may not even exist.

So just weeks ago, when Israeli scientists announced they’d found what they believe is a cure for cancer, the declaration sounded too good to be true. But here’s the thing:

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Glyphosate, the primary ingredient in Monsanto’s popular weed killer Roundup, has been linked to liver disease in animal models. In a new study, the first of its kind, researchers at the University of California San Diego School of Medicine report an association between the herbicide and negative effects upon the human liver.

In a study published in Clinical Gastroenterology and Hepatology, a team led by Paul J. Mills, Ph.D., professor and chief in the Department of Family Medicine and Public Health at UC San Diego School of Medicine, examined excretion in the of two —those with a diagnosis of NASH (non-alcoholic steatohepatitis, a type of nonalcoholic fatty or NAFLD), and those without. The results, they found, were significant: Regardless of age, race, body mass index (BMI), ethnicity or diabetes status, glyphosate residue was significantly higher in patients with NASH than it was in patients with a healthier liver.

The findings, coupled with prior animal studies, said Mills, suggest a link between the use of commercial glyphosate in our , which has increased significantly over the past 25 years, and the prevalence of NAFLD in the United States, which too has been on the rise for two decades.

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In breast cancer, there are cases of women and men whose cancer returns in their bones 20–30 years after they were treated for their primary disease and thought they were cancer-free. This phenomenon always puzzled Jefferson researcher Karen Bussard, Ph.D. How is it possible that breast cancer cells from a primary tumor are able to reach the bones when a patient is deemed “cancer-free” after treatment? What was happening in bones that allowed the cancer cells to remain there for up to 30 years, alive but in a sleeping state, only to re-awaken decades later? In a step towards answering these questions, Dr. Bussard recently discovered a type of bone cell that can subdue cancer cells, slowing their growth, even in one of the most aggressive types of breast cancer: triple negative.

The results, published in Breast Cancer Research, raise intriguing questions about how these exert their sleep-inducing influence, and whether it’s possible to replicate and permanently turn cancers dormant.

“Cancer has this uncanny ability to turn other cell types it comes in contact with to the cell’s advantage,” says Dr. Bussard, Assistant Professor of Cancer Biology at Thomas Jefferson University and a researcher at the Sidney Kimmel Cancer Center—Jefferson Health. “For example, cancer cells can turn the immune cells that should kill it, into its own guards. However, we have now found a population of bone cells that not only resists, but subdues the cancer. It’s fascinating.”

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A recent article, published in the Oxford journal Brain, categorizes and draws attention to an age-related disease that impacts the brain yet is widely unknown, even among scientists: limbic-predominant age-related TDP-43 encephalopathy (LATE) [1].

The symptoms of this disease are similar to those of Alzheimer’s disease. It causes cognitive impairment and, when presenting alongside Alzheimer’s disease, can lead to even faster degeneration along with heightened agitation and aggression.

This new disease has been found to impact very specific areas of the brain – generally traveling vertically through the brain, it degenerates areas partly responsible for emotions, memory, and language, influencing different areas depending on its stage.

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I’m excited to share my new #transhumanism article out at Metro, on of UK’s largest sites. It’s part of their #FutureofEverything series. Check out the artwork too:

Whatever science transhumanists want to use to become a better species, overcoming biological death is the movement’s primary goal.

Most deaths in the world are caused by ageing and disease. Approximately 150,000 people die every day on planet Earth, causing devastating loss to loved ones and communities.

I think the first step in getting this figure to decrease is for governments around the world to declare ageing a disease.

If society were to see ageing like it sees cancer or diabetes, then I believe more would be done to fight it.

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University of Sydney research provides new evidence that nanoparticles, which are present in many food items, may have a substantial and harmful influence on human health.

The study investigated the impacts of food additive E171 ( nanoparticles) which is commonly used in high quantities in foods and some medicines as a whitening agent. Found in more than 900 such as chewing gum and mayonnaise, E171 is consumed in high proportion everyday by the .

Published in Frontiers in Nutrition, the mice study found that consumption of food containing E171 has an impact on the gut microbiota (defined by the trillions of bacteria that inhabit the gut) which could trigger diseases such as inflammatory bowel diseases and colorectal cancer.

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Looking for perfect heat and lots of it? Gene engineers in Brazil think they might be able to create eye-watering tomatoes.

Hot stuff: Even though chili peppers and tomato plants diverged from a common ancestor millions of years ago, tomatoes still possess the genetic pathway needed to make capsaicinoids, the molecules that make chilis hot.

Now, Agustin Zsögön from the Federal University of Viçosa in Brazil writes in the journal Trends in Plant Science that gene-editing tools like CRISPR could turn it back on.

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Viruses are masterful invaders. They cannibalize host cells by injecting their genetic material, often making thousands of copies of themselves in a single cell to ensure their replication and survival.

Some RNA insert their genetic material as a single piece, while others chop it up into pieces. The latter are aptly named segmented viruses.

Such segmented RNA viruses—including several that cause human diseases like influenza—have been a longstanding enigma to researchers: How do they accomplish the precise copying and insertion of each segment? How do they ensure that individual segments are all copied by the same enzyme while ensuring that each segment can make different amounts of RNA? Such exquisite regulation is critical to make the correct levels of the viral proteins necessary for successful replication.

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