Lifeboat Foundation

Hundreds of millions of years ago, at a time when back-boned animals were just starting to crawl onto land, one such creature became infected by a virus. It was a retrovirus, capable of smuggling its genes into the DNA of its host. And as sometimes happens, those genes stayed put. They were passed on to the animal’s children and grandchildren. And as these viral genes cascaded through the generations, they changed, transforming from mere stowaways into important parts of their host’s biology.

One such gene is called Arc. It’s active in neurons, and plays a vital role in the brain. A mouse that’s born without Arc can’t learn or form new long-term memories. If it finds some cheese in a maze, it will have completely forgotten the right route the next day. “They can’t seem to respond or adapt to changes in their environment,” says Jason Shepherd from the University of Utah, who has been studying Arc for years. “Arc is really key to transducing the information from those experiences into changes in the brain.”

Weapons developers, disease fighters and food engineers were among the biggest winners in China’s top awards for scientists this year, giving a glimpse of the government’s research priorities.

Awards signal the government’s research priorities for the years to come, analyst says.

Researchers have found that by manipulating a single RNA molecule, they can reverse some aspects of cellular aging and regenerate aged cells.

Old cells resist regeneration

As we grow older, our cells gradually age, leading to the development of various diseases. Therefore, inducing cellular regeneration is one of the approaches that researchers are using to combat the age-related diseases associated with cellular aging. Unfortunately, aged cells are often highly resistant to therapies aimed at inducing regeneration.

Continue reading “Zeb2-NAT Molecule May Reverse Cellular Aging” »

Researchers at Duke University have managed to create functional human muscle tissue using skin cells as the starting point[1]. This research builds on their previous work from 2015, when they grew the first functioning muscle tissue using cells obtained from muscle biopsies[2].

Being able to create muscle cells using non-muscle tissue opens the door for scientists to grow muscle cells in bulk, provides an easier path to genome editing and gene therapies, offers a supply for basic research studies, and could help create personalized models for rare muscle diseases, leading to better patient outcomes.

http://www.playboy.com/articles/dna-to-find-the-one

Early Bird ends soon!

Have you got your tickets yet? If not, then you just have a few days to do so and save. Early Bird pricing ends on Monday, 11:59 pm CET.

The 2018 Undoing Aging Conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control.

Continue reading “The 2018 Undoing Aging Conference” »

Today’s vision of a smart home has more to do with what’s technologically possible than what people really need.

Thus the endless parade of internet-connected wine openers, water bottles, meat thermometers and refrigerators, and a dearth of automation that would clean and fold our laundry, pick up things around the house or assist aging people as their physical strength wanes.

Not that some tinkerers aren’t trying to come up with life-changing tools. The annual Consumer Electronics Show, which opened in Las Vegas on Tuesday, is a showcase of the latest innovations from big corporations and tiny startups. Some of these inventions could soon be useful to consumers. Others look outlandishly impractical — or maybe it’s too soon to tell.

Crowdsourcing the fight against drug-resistance infection.

Canadian doctors just reversed severe MS using stem cells.