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Machine learning finds a novel antibiotic able to kill superbugs

When tested in mice, the molecule, dubbed halicin, effectively treated the gastrointestinal bug Clostridium difficile (C. diff), a common killer of hospitalized patients, and another type of drug-resistant bacteria that often causes infections in the blood, urinary tract, and lungs.

The most surprising feature of the molecule? It is structurally distinct from existing antibiotics, the researchers said. It was found in a drug-repurposing database where it was initially identified as a possible treatment for diabetes, a feat that showcases the power of machine learning to support discovery efforts.

Surgeons successfully treat brain aneurysms using a robot

Using a robot to treat brain aneurysms is feasible and could allow for improved precision when placing stents, coils and other devices, according to late breaking science presented today at the American Stroke Association’s International Stroke Conference 2020.

Robotic technology is used in surgery and cardiology, but not for brain vascular procedures. In this study, Canadian researchers report the results of the first robotic brain vascular procedures. They used a robotic system specifically adapted for neurovascular procedures. Software and hardware adaptations enable it to accommodate microcatheters, guidewires and the other devices used for endovascular procedures in the brain. These modifications also provide the operator additional precise fine-motor control compared to previous system models.

“This experience is the first step towards achieving our vision of remote neurovascular procedures,” said lead researcher Vitor Mendes Pereira, M.D., M.Sc., a neurosurgeon and neuroradiologist at the Toronto Western Hospital, and professor of medical imaging and surgery at the University of Toronto in Canada. “The ability to robotically perform intracranial treatment is a major step forward in neuro-endovascular intervention.”

Coronavirus vaccine breakthrough in Australia

Australian scientists have made a key breakthrough in a desperate bid to develop a vaccine for the killer coronavirus.

Researchers at the University of Queensland are making a fast-tracked attempt to make a cure for the disease, which has killed more than 2,200 people worldwide.

There are now dozens of Australians suffering from the respiratory disease, with 47 contracting it on the Diamond Princess cruise ship in Japan.

The next chapter for African genomics

The rest of the world is interested, too. Africa contains much more genetic diversity than any other continent because humans originated there. This diversity can provide insights into human evolution and common diseases. Yet fewer than 2% of the genomes that have been analysed come from Africans. A dearth of molecular-biology research on the continent also means that people of African descent might not benefit from drugs tailored to unique genetic variations. Infectious-disease surveillance also falls short, meaning that dangerous pathogens could evade detection until an outbreak is too big to contain easily.


Nigeria is poised to become a hub for genetics research, but a few stubborn challenges block the way.

10 Italian towns in lockdown over coronavirus fears

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ROME: Authorities in northern Italy on Friday ordered the closure of schools, bars and other public spaces in 10 towns following a flurry of new coronavirus cases.

Five doctors and 10 other people tested positive for the virus in Lombardy, after apparently frequenting the same bar and group of friends, with two other cases in Veneto, authorities said at a press conference.

Over 50,000 people have been asked to stay at home in the areas concerned, while all public activities such as carnival celebrations, church masses and sporting events have been banned for up to a week.