Lifeboat Foundation

When you were a kid, did you ever sign a classmate’s cast after they broke an arm or a leg? Your name would be on display there for the rest of the semester. Broken bones are one of the worst trade-offs in childhood—a few seconds of calamity followed by months of boring rest and recovery. But children in the future may have a different story to tell as emerging tech overhauls how we fix broken bones.

Carbon nanomaterials may have the power to heal bones faster than a Harry Potter fan can say ‘Brackium Emendo!’ Researchers from Stefanie A. Sydlik’s team at Carnegie Mellon University have tested a new formulation of graphene that is biodegradable, mimics bone, attracts stem cells, and ultimately improves how animals can repair damage to their skeletons.

As reported in PNAS, this phosphate graphene serves as a scaffold, allowing the body’s own cells to more rapidly reform the missing or damaged bone. The technique has already shown success in mice. As this technology matures it could become a vital part of orthopedic medicine, helping us recover faster with stronger, healthier bones.

Continue reading “Graphene Shows Promise for Repairing Broken Bones” »

An antibody against the “don’t eat me” signal on cancer cells appears safe and well-tolerated by patients with advanced cancers. A phase 2 trial is planned.

Author Krista Conger Published on March 5, 2019 March 5, 2019.

President Trump’s tightened travel to Cuba makes it harder to go there. Some U.S. cancer patients say they have no other options.

Fluorocarbon based life? Could be possible. Wonder where this will go.

Chemists have now reported a facile method for the replacement of hydrogen with fluorine in important drug molecules. This new discovery enables the fine-tuning of existing (and potential new) pharmaceuticals to endow them with improved pharmacological properties.

The reported cure could lead to a gene-editing treatment for H.I.V.

A recently discovered Weyl semimetal delivers the largest intrinsic conversion of light to electricity of any material, an international team lead by a group of Boston College researchers reports today in the journal Nature Materials.

The discovery is based on a unique aspect of the material where electrons can be separated by their chirality, or handedness—similar to DNA. The findings may offer a new route to efficient generation of electricity from light, as well as for thermal or chemical sensing.

“We discovered that the Weyl semimetal Tantalum Arsenide, has a colossal bulk photovoltaic effect—an intrinsic, or non-linear, generation of current from light more than ten times larger than ever previously achieved,” said Boston College Associate Professor of Physics Kenneth Burch, a lead author of the article, titled “Colossal mid-infrared bulk photovoltaic effect in a type-I Weyl semimetal.”

Continue reading “Chirality yields colossal photocurrent” »

Native tribes used it to treat everything from sore muscles to headaches.

The announcement that a London man has become the second in the world to be “functionally cured” of HIV is a major advance in stem cell transplant therapy.

The man — who wishes to remain anonymous — was given stem cells from a donor with genetic resistance to the disease and he has now been in long term remission for 18 months without medication.

The breakthrough comes ten years after the first such case of a patient with HIV going into sustained remission, known as the ‘Berlin Patient.’

Continue reading “Advances in stem cell treatment give hope to millions with ‘incurable’ diseases” »

The role of epigenetics, which determine how your genes are expressed, is being increasingly implicated in aging, as is the potential of therapies that revert epigenetics back to those of a younger person.

What are epigenetic alterations?

The DNA in each of our cells is identical, with only some small variations, so why do our various organs and tissues look so different, and how do cells know what to become?

Continue reading “Epigenetic Alterations and Reprogramming Potential in Aging” »