Lifeboat Foundation

Will open avenues for drug discovery

Scientists have developed a new blood test for Alzheimer’s disease that can detect early indicators of the disease long before the first symptoms appear in patients. The blood test would thus open the door to new avenues in drug discovery, said the researchers from Ruhr University Bochum in Germany.

The blood test uses a technology called immuno-infrared sensor to measure distribution of pathological and healthy structures of amyloid-beta, according to a study published in the Molecular Cell. The pathological amyloid-beta structure is rich in a sticky, sheet-like folding pattern that makes it prone to aggregation, while the healthy structure is not.

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I t has now been decades since stem cell technology emerged as the next great breakthrough in modern medicine, with the bold potential for one day curing everything from heart disease to cancer. Today, that optimism doesn’t appear to have diminished.

It’s easy to recall the excitement. In the late 1990s, when stem cell research was still relatively unexplored but gathering pace, the hope surrounding future uses for such treatments appeared near limitless. Once greater advances had been made, it was often argued, doctors could one day inject patients with cells that have the ability to transform into any other type of cell, making it possible to grow whole new organs. In theory, any damaged area…

Scientists have discovered that a particular type of lipid, or fat—thought to only exist in the skin—lives in your eye and could have a part in preventing diabetic retinopathy.

An early symptom is blurry vision in which straight lines appear distorted. That can progress to darkness, whiteouts, or blurry areas in the center of the visual field. The disease does not, by itself, lead to total blindness because peripheral vision remains unaffected. Although some therapies delay loss of central vision, no current treatments restore it completely.

“Macular degeneration therapies seem to be treating disease symptoms, rather than its cause,” Lin says. “We focused on the role of macrophages in regulating inflammation and the growth of abnormal blood vessels to see whether it may be possible one day to help people who don’t get much benefit from existing treatments and design therapies that may prevent progression to advanced forms of the disease.”

Virus delivers genes to fight vision loss.

On April 2, 1845, Armand Hippolyte Louis Fizeau and Jean Bernard Léon Foucault manage to make the very first photography of the Sun. Thereby, they both initiate astronomical photography.

From a previous blog post you may remember Léon Foucault’s Pendulum.[4] The instrument was used to proof Earth’s rotation in the 1850s and counts to one of Foucault’s biggest scientific achievements. But let’s start a little bit earlier. Leon Foucault was born on September 18, 1819 as the son of a publisher in Paris. After an education received chiefly at home, he studied medicine, which he abandoned in favour of physics due to a fear of blood.

Meanwhile, astronomical photography started to establish slowly. There were not many experts in the field back then, since the very long exposures needed to capture relatively faint astronomical objects and many technological problems had to be overcome. Completely new telescopes had to be developed that were rigid enough in order to not lose the focus during exposure time. Also the telescopes had to be attached to a rotating mount that would move at a constant rate very accurately. Next to the telescope building itself, the technology of photography needed improvement as well. The daguerreotype was just introduced in 1839 and came into a very widespread use. However, for astronomical photography, the process was too slow and was only able to record very bright objects. Also, the exposure time was very limited using this method due to the wet plate collodion process.

DIYers can bioprint living human organs by modifying an off-the-shelf 3D printer costing about $500, announce researchers who published the plans as open source, enabling anyone to build their own system. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

Scientists at Carnegie Mellon University (CMU) developed a low-cost 3D bioprinter to print living tissue by modifying a standard desktop 3D printer and released the design as open source so that anyone can build their own system.

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In brief: An implantable cancer vaccine from Harvard has shown promising results in mice, and researchers are testing it in a clinical trial on humans. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

An implantable cancer vaccine being tested on patients by Harvard’s Wyss Institute is a new type of immunotherapy that holds promise to treat a wide range of cancers such as melanoma, as well as auto-immune conditions and infectious diseases. The aspirin-sized implant is made of a polymer scaffold containing growth factors and tissue samples from a patient’s tumors which trains a patient’s immune system to search and destroy cancer cells.

Harvard’s cancer vaccine is approaching the end of clinical testing, promising to be available 4 or 5 years sooner than Stanford’s vaccine with its 97% cure rate.

S cientists have warned against the risks of intensive IVF treatment as research suggests it increases the risk of heart disease in children.

The “high stimulation” method, where powerful drugs are used to stimulate egg production, is a commonly used practise in British fertility clinics.

But experts are now claiming there is growing evidence the treatment can result in offspring with higher blood pressure and thicker arteries than normal.

Continue reading “IVF children at risk of heart disease if procedure too intense, experts warn” »

Researchers and scientists say new discoveries and drug creation could be beneficial to future astronauts on deep space missions.

Sarah Betancourt