William G. Kaelin, Jr., of the Dana-Farber Cancer Institute and Harvard University, Sir Peter J. Ratcliffe, of Oxford University and the Francis Crick Institute, and Gregg L. Semenza, of Johns Hopkins University were jointly awarded the prize.
Category: biotech/medical – Page 2020
The complex interplay of various processes and mechanisms that contribute to aging means it’s unlikely we’ll discover a single “magic bullet” to prevent age-related diseases. But new research led by University College London and the Max Planck Institute for Biology and Ageing is potentially as close as anything we’ve seen. The scientists have been able to extend the lifespan of fruit flies by 48 percent using a triple drug combination made up of drugs already used in people.
“As life expectancies increase, we are also seeing an increase of age-related diseases so there is an urgent need to find ways to improve health in old age,” says study co-lead author, Dr Jorge Castillo-Quan. “Here, by studying fruit flies which age much more rapidly than people, we have found that a combination drug treatment targeting different cellular processes may be an effective way to slow down the aging process.”
The three drugs making up the combo include lithium, which is used as a mood stabilizer, trametinib, a cancer drug that inhibits MEK1 and MEK2 enzymes, and rapamycin, an immune system regulator produced by bacteria that was first found in a soil sample from Easter Island and has been found to improve learning and memory in mice.
More than 100 people in North Carolina were sickened with Legionnaires’ disease and Pontiac fever last month. One person died.
Sajad Zalzala wants to enable off-label uses of common drugs, like Metformin, to slow aging.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Ambassador Juan José Gómez Camacho, Mexico’s current Ambassador to Canada, and for the last 3 years, Mexico’s Permanent Representative of the United Nations in New York City.
Ira Pastor Comments:
Today, we are going to talk about a fascinating series of topics related to global population health, and we will start by citing some staggering data.
The World Health Organization (WHO) estimates that there are around 1 billion migrants in the world today. 258 million of them are international migrants and 763 million are internal migrants, that’s one in seven of the world’s population.
Gut microbiome affect metabolic and neural diseases through alterations in epigenetic expressions by DNA methylation and miRNA modulations.
Steven Gundry, MD, author of The Longevity Paradox: How to Die Young at a Ripe Old Age, explains how he boosted patients’ lifespan and healthspan by combining conventional medicine with nutritional therapy.
Bank employs AI-powered “digital DNA human”
Arab Banking Corporation (Bank ABC), in collaboration with New Zealand tech company, Soul Machines, has announced the launch of “Fatema” – a fully autonomous AI personality that will assist customers online.
This “digital employee” can accumulate experiences, learn, and respond to people individually, therefore adding human-like qualities to the AI. Fatema will work alongside Bank ABC’s mobile-only digital bank (to be launched by end of this year) to offer a multi-faceted, personalised customer experience.
Researchers are working to get to the bottom of longevity, unlocking the secrets to extending our lifespans well into our 100s… and beyond.
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Harvard Professor David Sinclair thinks longevity, or extending our lifespan, is the “greatest unsolved problem in biology.”
The global life expectancy is currently hovering somewhere around 72 years old and women typically live longer than men and the age tends to be higher in developed countries and lower in impoverished nations.
Some experts argue that the tools we currently have when it comes to extending our lifespans are as simple as diet and exercise, but a healthy diet is only going to get you so far. So scientists are seeking out clues in the natural world that could help us side step growing old, some scientists even think that many of the ailments we refer to as diseases could be thought of as the symptoms of aging.