He Jiankui, who went to prison for three years for making the world’s first gene-edited babies, talked to MIT Technology Review about his new research plans.
Category: biotech/medical – Page 191
Stress sensitive neural circuits change the gut microbiome and the duodenal glands.
Precision mapping of a gut-brain circuit w/ functional impact.
Glands in the small intestine (Brunner’s) have GLP-1 receptors, are stress-sensitive, connect to the brain via the vagal nerve, modulate bacterial…
Stress leads to disarray of the gut microbiome, which in turn causes inflammation and a drop in the body’s ability to fend off infection.
Programmable and reversible CRISPRi-based genetic circuits function in a variety of plants.
What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and Oxford, in collaboration with the University Medical Center Göttingen (UMG), have succeeded in developing a microscope with resolutions better than five nanometers (five billionths of a meter). This is roughly equivalent to the width of a hair split into 10,000 strands. Their new method was published in Nature Photonics.
Microbe found in cat poo could be harnessed to deliver large, complex proteins across the blood–brain barrier.
As a medical scientist, he looks at how new findings will help develop new treatments to revive people now considered hopeless and restore brain damage.
The Cygnus spacecraft is filled with nearly 8,200 pounds of supplies, hardware and other critical materials for dozens of scientific and research experiments, according to NASA.
That includes tests for water recovery technology and supplies needed for a process to produce blood and immune stem cells in microgravity. Also included in the payload are materials to study the effects of spaceflight on engineered liver tissue and microorganism DNA, NASA said.
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Pain management is an important component of caring for adults with cerebral palsy. However, it’s the least understood comorbidity in the adult cerebral palsy population.
A study led by Mark Peterson, Ph.D., M.S., FACSM, a professor of physical medicine and rehabilitation at University of Michigan Health, found that adults living with cerebral palsy had a very high occurrence of pain, with 90% having a pain history and 74% having multiple diagnoses of pain coming from different origins such as the lower back, irritable bowels, joint arthritis and chronic headaches.
The research is published in the journal JAMA Neurology.
Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children’s Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.
The preclinical findings were published in the journal Proceedings of the National Academy of Sciences.
Last year, a multi-institutional consortium of researchers found that the genes of the mitochondria, the energy producers of our cells, can be negatively impacted by the virus, leading to dysfunction in multiple organs beyond the lungs.