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Two documents dating back to 2015 shed further light on the role the federal government played in discovering remdesivir and its use in treating coronaviruses — work that has taken on new meaning as the Gilead Sciences (GILD) drug has gained global attention and an emergency use authorization from federal regulators to treat patients with Covid-19.


Reporting from the frontiers of health and medicine.

The maker of a drug shown to shorten recovery time for severely ill COVID-19 patients says it will charge $2,340 for a typical treatment course for people covered by government health programs in the United States and other developed countries.

Gilead Sciences announced the price Monday for remdesivir, and said the price would be $3,120 for patients with private insurance. The amount that patients pay out of pocket depends on insurance, income and other factors.

“We’re in uncharted territory with pricing a new medicine, a novel medicine, in a pandemic,” Gilead’s chief executive, Dan O’Day, told The Associated Press.

Research at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has led to the revolutionary development of an artificial liquid retinal prosthesis to counteract the effects of diseases such as retinitis pigmentosa and age-related macular degeneration that cause the progressive degeneration of photoreceptors of the retina, resulting in blindness. The study has been published in Nature Nanotechnology.

The study represents the state of the art in retinal prosthetics and is an evolution of the planar artificial retinal model developed by the same team in 2017 and based on organic semiconductor materials (Nature Materials 2017, 16: 681–689).

The ‘second generation’ artificial retina is biomimetic, offers and consists of an aqueous component in which photoactive polymeric nanoparticles (whose size is 350 nanometres, thus about 1/100 of the diameter of a hair) are suspended, and will replace damaged photoreceptors.

The spiral pattern shown by the galaxy in this image from the NASA /ESA Hubble Space Telescope is striking because of its delicate, feathery nature. These “flocculent” spiral arms indicate that the recent history of star formation of the galaxy, known as NGC 2775, has been relatively quiet. There is virtually no star formation in the central part of the galaxy, which is dominated by an unusually large and relatively empty galactic bulge, where all the gas was converted into stars long ago.

NGC 2275 is classified as a flocculent spiral galaxy, located 67 million light-years away in the constellation of Cancer.

Millions of bright, young, blue stars shine in the complex, feather-like spiral arms, interlaced with dark lanes of dust. Complexes of these hot, blue stars are thought to trigger star formation in nearby gas clouds. The overall feather-like spiral patterns of the arms are then formed by shearing of the gas clouds as the galaxy rotates. The spiral nature of flocculents stands in contrast to the grand design spirals, which have prominent, well defined-spiral arms.

Disinfecting spaces such as warehouses is especially critical during the COVID-19 pandemic, but doing so while keeping workers safe can be challenging. So MIT’s Computer Science and Artificial Intelligence Laboratory came up with a solution: use a robot that employs UV-C light to disinfect surfaces and neutralize aerosolized forms of coronavirus.

Through a collaboration with Ava Robotics and the Greater Boston Food Bank, CSAIL mounted a custom UV-C lamp on an Ava Robotics mobile robot base. The lamp neutralizes around 90% of surface microorganisms, according to CSAIL. The robot is initially operated by a remote user and subsequently works autonomously, and can disinfect 4,000 square feet of warehouse space in half an hour.

The Chinese government is taking draconian measures to slash birth rates among Uighurs and other minorities as part of a sweeping campaign to curb its Muslim population, even as it encourages some of the country’s Han majority to have more children.

While individual women have spoken out before about forced birth control, the practice is far more widespread and systematic than previously known, according to an AP investigation based on government statistics, state documents and interviews with 30 ex-detainees, family members and a former detention camp instructor. The campaign over the past four years in the far west region of Xinjiang is leading to what some experts are calling a form of “demographic genocide.”

The state regularly subjects minority women to pregnancy checks, and forces intrauterine devices, sterilization and even abortion on hundreds of thousands, the interviews and data show. Even while the use of IUDs and sterilization has fallen nationwide, it is rising sharply in Xinjiang.

In the average human body, tens of billions of cells die everyday. It’s a natural process, important for keeping the body healthy. Now, for the first time, researchers at Yale School of Medicine have directly imaged the death of neurons in mice, as well as how the body clears them out afterwards.

Although it might seem like brain cells are things you’d definitely want to keep around, it’s better to get rid of the ones that aren’t working. After all, a build-up of dead cells can damage the nervous system and has been implicated in neurodegenerative diseases.

To prevent this, the brain – and indeed the rest of the body – has a natural process that clears out dead cells. But scientists haven’t been sure about the exact mechanisms at work during this cellular “corpse removal” process.