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Neural Network Reveals New Insights Into How the Brain Functions

Summary: A new computational method sheds light on the intricacies of brain structure and function.

Source: Baylor College of Medicine.

To better appreciate how a complex organ such as the brain functions, scientists strive to accurately understand both its detailed cellular architecture and the intercellular communications taking place within it.

No Need To Fear The Ghost Kitchens Of Christmas Future

As the holidays approach, gifts are being bought, and plans are being made with family and friends. These typical holiday activities are contributing to the growth of e-commerce — which has already been accelerated by the COVID-19 pandemic. Food now represents an important part of the e-commerce landscape. Chances are if you are planning to see some friends and family, you may already be thinking about where to eat, what to eat, and how best to plan it all. The good news is that there are many more options today than there were even 5 years ago.

Food delivery — from restaurant food to groceries to well-designed ingredient bundles that remove the hassle of meal planning are all available with ‘one click’. Due to COVID and the various restrictions, concern for public health, and even lockdowns millions of people have taken the leap and ordered food online for the first time.

Coming from a mobility perspective, it is interesting to note what is happening in the food industry because at the end of the day it will require new innovations and solutions to deliver the food to people’s doors. And even better will be when those mobility solutions are more sustainable and efficient than what is being used today. With the boom in this sector, it isn’t just about switching from internal combustion engines to zero-emission, but also pushing for new form factors that can further increase efficiency (lowering the cost and energy demand).

Step forward in quest to develop living construction materials and beyond

Some engineered living materials can combine the strength of run-of-the-mill building materials with the responsiveness of living systems. Think self-healing concrete, paint that changes color when a specific chemical is detected or material that could reproduce and fill in a crack when one forms. This would revolutionize construction and maintenance, with wide-reaching economic and environmental implications.

Seeing this new category of adaptive materials on consumer shelves may be a ways off. Still, critical early research from the University of Minnesota sheds new light on this exciting advancement, which shows promise beyond building materials, including biomedical applications.

In a new study in Nature Communications, researchers from the College of Biological Sciences demonstrate how to transform silica — a common material used in plaster and other construction materials — into a self-assembling, dynamic and resilient material.

Stopping arthritis before it starts

More than a million Americans undergo knee and hip replacements each year. It’s a last resort treatment for pain and mobility issues associated with osteoarthritis, a progressive disease caused by degeneration of the protective layer of cartilage that stops our bones grinding together when we sit, stand, write, or move around.

But what if doctors could intervene and repair damaged cartilage before surgery is needed?

For the first time, researchers at the Keck School of Medicine of USC have used a stem cell-based bio-implant to repair cartilage and delay joint degeneration in a large animal model. The work will now advance into humans with support from a $6 million grant from the California Institute of Regenerative Medicine (CIRM).

A colon growth hormone could pave way for treating aging-related disorders

Researchers say they have found a growth hormone in the colon that helps damage DNA, which aides in the aging process. The finding could lead to new therapeutic approaches to aging-associated disorders like cancer.

Whereas circulating pituitary growth hormones decline with age, non-pituitary growth hormones, or npGH, increase with age. That means the colon tissue growth hormone helps initiate the first stages of tumor development and influence the aging process, Cedars-Sinai Medical Center researchers said in research published in the journal Cell Reports.

At the core of the issue is npGH blocking a certain protein from protecting DNA from damage. The protein, p53, is a tumor suppressor that helps repair DNA, but it can also awaken growth hormones.

FDA Just Approved The World’s First Injectable Medication to Prevent HIV

The world’s first injectable medication to reduce the risk of acquiring HIV has been approved by the Food and Drug Administration (FDA), the agency announced Monday (December 20).

The injectable drug – called Apretude or its generic name, “cabotegravir extended-release injectable suspension” – provides an alternative to daily pills for HIV prevention, such as Truvada and Descovy. These pills are up to 99 percent effective at preventing the sexual transmission of HIV, but must be taken every day to be that effective, according to the Centers for Disease Control and Prevention (CDC).

By contrast, to start Apretude, people initially receive two shots, spaced one month apart, and then they receive an injection every two months thereafter, according to the FDA statement.

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