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Category: biotech/medical – Page 1,670

Summary: Gene expression patterns in four regions of the prefrontal cortex are distinctly different in those who have been diagnosed with PTSD compared to those who have not. Major differences were seen in interneurons, which inhibit the immune system and microglia in the central nervous system. Findings shed light on why women are more likely to experience PTSD and compound a link between post-traumatic stress and a dampening of the immune system.

Source: Yale.

A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team headed by Yale University researchers has found.

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Scientists from Nanyang Technological University, Singapore (NTU Singapore), have developed a new way to cure adhesives using a magnetic field.

Conventional adhesives like epoxy which are used to bond plastic, ceramics and wood are typically designed to cure using moisture, heat or light. They often require specific curing temperatures, ranging from room temperature up to 80 degrees Celsius.

The curing process is necessary to cross-link and bond the glue with the two secured surfaces as the glue crystallizes and hardens to achieve its final strength.

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We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs. Irina and Michael Conboy.

Some molecules, while essential for various body functions, can be harmful when overproduced. Inflammatory cytokines, such as transforming growth factor beta 1 (TGF-ß1), interleukin 6 (IL6), and tumor necrosis factor alpha (TNFa) are good examples. The concentration of these cytokines in our blood rises with age, provoking inflammaging, the chronic inflammation that is associated with aging. It has been long speculated that reducing the harmful molecules in circulation can attenuate aging.

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Preliminary results suggest anti-COVID19 nanobodies may be effective at preventing and diagnosing infections.

National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or “nanobodies,” against SARS-CoV-2 that were produced by a llama named Cormac. Preliminary results published in Scientific Reports suggest that at least one of these nanobodies, called NIH-CoVnb-112, could prevent infections and detect virus particles by grabbing hold of SARS-CoV-2 spike proteins. In addition, the nanobody appeared to work equally well in either liquid or aerosol form, suggesting it could remain effective after inhalation. SARS-CoV-2 is the virus that causes COVID-19.

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A generation after a NASA spacecraft’s probe found an unexpectedly hot and dense atmosphere at Jupiter, a newer agency mission may have some answers to the puzzle.

NASA’s Juno spacecraft discovered that these “hot spots” on the gas giant planet — which the Galileo spacecraft discovered in 1995 — are wider and deeper than previous models and observations suggest, according to results revealed Dec. 11 at the American Geophysical Union’s annual fall conference, held virtually this year due to the coronavirus pandemic.

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One of the ongoing questions these past few months has been why so many tech products have been so hard to buy. We’ve made repeated reference to known potential factors like COVID-19, economic disruptions, yield issues, and the impact of scalping bots, but there’s a new argument for what’s causing such general problems across so many markets: Insufficient investment in 200mm wafers.

Today, leading-edge silicon is invariably manufactured on 300mm wafers. Over the past few decades, manufacturers have introduced larger wafer sizes: 100mm, 150mm, 200mm, and 300mm have all been common standards at one time or another. In the PC enthusiast space, 300mm wafers have long been considered superior to 200mm wafers, because the larger wafer size reduces waste and typically improves the foundry’s output in terms of chips manufactured per day.

There aren’t that many commercial foundries still dedicated to 150mm or smaller wafer sizes, but a number of foundries still run 200mm fab lines. TSMC and Samsung both offer the node, as well as a number of second-tier foundries. GlobalFoundries has 200mm facilities, as do SMIC, UMC, TowerJazz, and SkyWater. A great many IoT and 5G chips are built on 200mm, as are some analog processors, MEMS devices, and RF solutions.

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As we approach the end of 2020, according to the U.S. National Cancer Institute (NCI), we have had approximately 1, 806, 590 new cases of cancer diagnosed in the United States, with 606, 520 deaths. Cancer continues to be the leading causes of death worldwide. In 2018, there were 18.1 million new cases and 9.5 million cancer-related deaths worldwide.

By 2040, the number of new cancer cases per year is expected to rise to 29.5 million and the number of cancer-related deaths to 16.4 million.

Dr. Azra Raza, MD, is the Chan Soon-Shiong Professor of Medicine, in the Department of Medicine, Division of Hematology / Oncology, and Director of the Myelodysplastic Syndrome (MDS) Center, at the Columbia University Medical Center.

Previously, Dr. Raza was the Chief of Hematology-Oncology and the Gladys Smith Martin Professor of Oncology at the University of Massachusetts.

Dr. Raza is an international authority on pre-leukemia / MDS, and acute leukemia, and is both a physician and scientist who divides her time equally between caring for patients and supervising a state-of-the-art basic research lab which is well-funded by multiple large grants. Dr. Raza started collecting blood and marrow samples on her patients in 1984 and now her Tissue Bank, the largest and oldest in the country with over 60, 000 samples, is considered a unique national treasure.

Dr. Raza has published her original clinical and basic research comprising over 300 peer-reviewed manuscripts in high profile journals like Nature, New England Journal of Medicine, Cell, Molecular Cell, Cancer Research, Blood, Leukemia.

Continue reading “Dr. Azra Raza — Anticipate, Find, And Destroy The FIRST Cancer Cell; STOP The Disease In Its Tracks” | >