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Gene editing can turn storage fat cells into energy-burning fat cells

A team of researchers at UT Southwestern Medical Center’s Touchstone Diabetes Center have successfully used CRISPR gene editing to turn fat cells normally used for storage into energy-burning cells.

“It’s like flipping a switch. We removed the ‘brake’ on the energy burning pathway in by engineering a mutation that disrupts the interaction between a single pair of proteins,” said study leader Rana Gupta, Ph.D., Associate Professor of Internal Medicine. “Our research demonstrates that releasing this brake in fat cells can potentially help make existing much more effective.”

The research at UT Southwestern, ranked as one of the nation’s top 25 hospitals for diabetes and endocrinology care, is published in Genes and Development and supported by the National Institutes of Health.

Deep North, which uses AI to track people from camera footage, raises $16.7M

Deep North, a Foster City, California-based startup applying computer vision to security camera footage, today announced that it raised $16.7 million in a Series A-1 round. Led by Celesta Capital and Yobi Partners, with participation from Conviction Investment Partners, Deep North plans to use the funds to make hires and expand its services “at scale,” according to CEO Rohan Sanil.

Deep North, previously known as Vmaxx, claims its platform can help brick-and-mortar retailers “embrace digital” and protect against COVID-19 by retrofitting security systems to track purchases and ensure compliance with masking rules. But the company’s system, which relies on algorithms with potential flaws, raises concerns about both privacy and bias.

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Russia registers ‘world’s first’ COVID-19 vaccine for dogs, cats and other animals

Russia has registered the world’s first COVID-19 vaccine for animals, the country’s agricultural regulator said on Wednesday.

Clinical trials of the vaccine — called Carnivac-Cov — started last October and involved dogs, cats, Arctic foxes, minks, foxes and other animals, said Konstantin Savenkov, deputy head of Rosselkhoznadzor, according to a Reuters report.

Artificial Muscles Robotic Arm Full Range of Motion + Static Strength Test (V11)

We have achieved strong, fast, power-dense, high-efficiency, biomimetic, soft, safe, clean, organic and affordable robotic technology. Dumbbell weights 7 kg (15,6 lbs) 0 forearm with hand only 1 kg (2,2 lbs).

This artificial muscles robotic arm is operated by water and consumes 200W at peak. We invent and produce portable power supply and our own electro-hydraulic mini valves to have complete controllability of speed contraction and compress the whole powering system (for a full body) inside humanlike robot torso.

At this moment our robotic arm is operated only by a half of artificial muscles when compared to a human body. Strongest finger-bending muscle still missing. Fingers are going to move from left to right but they don’t have muscles yet. Metacarpal and left-to-right wrist movement are also blocked. This version has a position sensor in each joint but they are yet to be software-implemented. We are going to add everything mentioned above in the next prototype.

The movement sequence was written and sent by simple commands to a hand. We wish to develop a platform for reinforcement learning purposes, prosthetic arms and ultimately a full humanoid robots to serve people for fun, as butlers, cleaners, chauffeurs, construction workers (also in space) and even achieve human immortallity by transplanting the brain into the machine.

If you want to see updates on the project, please share, like, comment and hit that subscribe button. You can also support us directly on Patreon:
https://www.patreon.com/automatonrobotics.

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A ‘Historic Event’: First Malaria Vaccine Approved by W.H.O

The world has gained a new weapon in the war on malaria, among the oldest known and deadliest of infectious diseases: the first vaccine shown to help prevent the disease. By one estimate, it will save tens of thousands of children each year.

Malaria kills about half a million people each year, nearly all of them in sub-Saharan Africa — including 260,000 children under 5. The new vaccine, made by GlaxoSmithKline, rouses a child’s immune system to thwart Plasmodium falciparum, the deadliest of five malaria pathogens and the most prevalent in Africa.

The World Health Organization on Wednesday endorsed the vaccine, the first step in a process that should lead to wide distribution in poor countries. To have a malaria vaccine that is safe, moderately effective and ready for distribution is “a historic event,” said Dr. Pedro Alonso, director of the W.H.O.’s global malaria program.

Pig kidney attached to human found to work normally

Surgeons have successfully attached a pig’s kidney to a human and confirmed that the body accepted the transplant in a major scientific breakthrough, The New York Times reported.

This successful operation is a promising sign as scientists work to be able to use animal organs in life-saving transplants in humans.

Scientists altered a pig gene and engineered the kidney to eliminate sugar to avoid an immune system attack. In the past, the human body would reject the transplant due to the presence of glycan, a sugar molecule in pig cells.

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