Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1,618

“We’re excited to share that AWS has acquired Wickr, an innovative company that has developed the industry’s most secure, end-to-end encrypted, communication technology,” Stephen Schmidt, Amazon Web Services’ vice president, wrote. With a nod to the company’s ever-deepening relationships with the military, and Washington in general, Schmidt added that Wickr’s features give “security conscious enterprises and government agencies the ability to implement important governance and security controls to help them meet their compliance requirements.” Schmidt himself has a background in this space: his LinkedIn profile notes he spent a decade at the FBI.

Wickr’s app — like secure messaging competitor Signal — has been popular with journalists and whistleblowers; it’s also been a go-to for criminals, Motherboard notes. It’s unclear if the proximity to the tech monolith will impact the app’s popularity for free users.

In Amazon’s case, Schmidt indicates the acquisition was at least partially influenced by the need to preserve information security while working remotely. “With the move to hybrid work environments, due in part to the COVID-19 pandemic, enterprises and government agencies have a growing desire to protect their communications,” he wrote.

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STANFORD, Calif. — A groundbreaking “superhero” vaccine inspired by the DNA code of Olympic athletes could help transform society over the next decade, a top genetic scientist claims.

The vaccine would provide lifelong protection against three of the top ten leading causes of death, according to Euan Ashley, professor of medicine and genetics at Stanford University. The so-called “superhero” jab could offer simultaneous, long-term protection against heart disease, stroke, Alzheimer’s disease, and liver disease, thanks to advances in genetic engineering.

This breakthrough treatment would deliver the blueprint of “ideal” cells from men and women whose genes are more disease-resistant than those of the average person, together with an “instruction manual” to help the body “repair, tweak and improve” its own versions. A single dose could lead to a “body-wide genetic upgrade” that would cut the risk of premature death in some adults by as much as 50 percent.

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“At first, we had a hard time believing the results. Many of these genes are classical hallmarks of aging and yet our results suggested that their activity is more a function of the presence of bacteria rather than the aging process,” said Dr. Shukla.

Notably, this included genes that control stress and immunity. The researchers tested the impact that the antibiotics had on these genes by starving some flies or infecting others with harmful bacteria and found no clear trend. At some ages, the antibiotics helped flies survive starvation or infection longer than normal whereas at other ages the drugs either had no effect or reduced the chances of survival.

NIH scientists discover that bacteria may drive activity of many hallmark aging genes in flies.

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I am waiting for tricorders.

The idea of visiting the doctor’s office with symptoms of an illness and leaving with a scientifically confirmed diagnosis is much closer to reality because of new technology developed by researchers at McMaster University.

Engineering, biochemistry and medical researchers from across campus have combined their skills to create a hand-held rapid test for bacterial infections that can produce accurate, reliable results in less than an hour, eliminating the need to send samples to a lab.

Their proof-of-concept research, published today in the journal Nature Chemistry, specifically describes the test’s effectiveness in diagnosing urinary tract infections from real clinical samples. The researchers are adapting the test to detect other forms of bacteria and for the rapid diagnosis of viruses, including COVID-19. They also plan to test its viability for detecting markers of cancer.

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Circa 2015 In theory this big bang laser could eventually create complex matter but would need to be pocket-size as I want it on a smartphone to make a replicator so I can make fruit or food in space 😀

The Institute of Laser Engineering (ILE), Osaka University, has succeeded to reinforce the Petawatt laser “LFEX” to deliver up to 2000 trillion watts in the duration of one trillionth of one second (this corresponds to 1000 times the integrated electric power consumed in the world). By using this high-power laser, it is now possible to generate all of the high-energy quantum beams (electrons, ions, gamma ray, neutron, positron). Owing to such quantum beams with large current, we can make a big step forward not only for creating new fundamental technologies such as medical applications and non-destructive inspection of social infrastructures to contribute to our future life of longevity, safety, and security, but also for realization of laser fusion energy triggered by fast ignition.

Background and output of research

Petawatt lasers are used for study of basic science, generating such high-energy quantum beams as neutrons and ions, but only a few facilities in the world have Petawatt laser. So far, Petawatt lasers in the world have had relatively a small output (to a few tens of joules). ILE has achieved the world’s largest laser output of dozens of times those at other world-class lasers facilities (1000 joules or more).

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In a study in Nature Plants, Yiping Qi, associate professor of Plant Science at the University of Maryland (UMD), introduces a new and improved CRISPR 3.0 system in plants, focusing on gene activation instead of traditional gene editing. This third generation CRISPR system focuses on multiplexed gene activation, meaning that it can boost the function of multiple genes simultaneously. According to the researchers, this system boasts four to six times the activation capacity of current state-of-the-art CRISPR technology, demonstrating high accuracy and efficiency in up to seven genes at once. While CRISPR is more often known for its gene editing capabilities that can knock out genes that are undesirable, activating genes to gain functionality is essential to creating better plants and crops for the future.

“While my lab has produced systems for simultaneous gene editing [multiplexed editing] before, editing is mostly about generating loss of function to improve the crop,” explains Qi. “But if you think about it, that strategy is finite, because there aren’t endless genes that you can turn off and actually still gain something valuable. Logically, it is a very limited way to engineer and breed better traits, whereas the plant may have already evolved to have different pathways, defense mechanisms, and traits that just need a boost. Through activation, you can really uplift pathways or enhance existing capacity, even achieve a novel function. Instead of shutting things down, you can take advantage of the functionality already there in the genome and enhance what you know is useful.”

In his new paper, Qi and his team validated the CRISPR 3.0 system in rice, tomatoes, and Arabidopsis (the most popular model plant species, commonly known as rockcress). The team showed that it is possible to simultaneously activate many kinds of genes, including faster flowering to speed up the breeding process. But this is just one of the many advantages of multiplexed activation, says Qi.

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Other companies, including BlueNalu Inc., Upside Foods Inc. and Eat Just, have expressed an intention to sell cell-based products in the U.S. Like them, Future Meat must get approval from the U.S. Department of Agriculture and the Food and Drug Administration before offering its products to the public. Kshuk is optimistic, though reaching price parity with conventional meat will probably take the nascent industry a few years.

An Israeli startup wants to replace chicken coops, barns and slaughterhouses with bioreactors to churn out cell-based meat for American diners.

Future Meat Technologies Ltd. is in talks with U.S. regulators to start offering its products in restaurants by the end of next year. The company has just opened what it calls the world’s first industrial cellular meat facility, which will be able to produce 500 kilograms (1102 pounds) a day.

“From the get-go, our main focus was around scaling up and reducing cost in order to have a commercially viable product,” Chief Executive Officer Rom Kshuk said in an interview.

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Two teams of researchers took part in the dramatic discovery, published in the prestigious Science journal: an anthropology team from Tel Aviv University headed by Prof. Israel Hershkovitz, Dr. Hila May and Dr. Rachel Sarig from the Sackler Faculty of Medicine and the Dan David Center for Human Evolution and Biohistory Research and the Shmunis Family Anthropology Institute, situated in the Steinhardt Museum at Tel Aviv University; and an archaeological team headed by Dr. Yossi Zaidner from the Institute of Archaeology at the Hebrew University of Jerusalem.

Timeline: The Nesher Ramla Homo type was an ancestor of both the Neanderthals in Europe and the archaic Homo populations of Asia.

Prof. Israel Hershkovitz: “The discovery of a new type of Homo” is of great scientific importance. It enables us to make new sense of previously found human fossils, add another piece to the puzzle of human evolution, and understand the migrations of humans in the old world. Even though they lived so long ago, in the late middle Pleistocene (474000−130000 years ago), the Nesher Ramla people can tell us a fascinating tale, revealing a great deal about their descendants’ evolution and way of life.”

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