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Category: biotech/medical – Page 1,488

Eurolink Systems to launch multi-mission ready Beluga mini drone

Italian company EuroLink Systems, a technology solutions manufacturer with decades of industry experience, will launch the Beluga mini drone, a dual-use aircraft ready to deploy anywhere from the desert to the arctic, at next week’s Xponential 2022 in Orlando.

The new state-of-the-art multirotor drone blends a bio-inspired design with high-performance features that make it suitable for a wide variety of tasks – from military or public safety applications like short-range reconnaissance, search & rescue, or security applications to commercial use in 3D terrain mapping, urban logistics support applications, threat detections, and urgent medical transportation.

Beluga has been in development for three years and combines Eurolink Systems’ technical experience with mother nature shapes, resulting in an elegant design and rich technical functionality – that represents the best of art and science. The drone can fly fast, with a maximum cruising speed of up to 112 km/h (69 mph), for up to 60 minutes with a 3.3 lbs. (1.5 kg) payload.

Residents in locked down Shanghai scream from their balconies: ‘This cannot last’

For those not paying attention, Tesla has been unable to build cars in China for a few weeks as China shuts down due to a zero Covid policy. Here’s a short video about life in China:

China’s financial hub Shanghai has started easing its lockdown in some areas on Monday, despite reporting a record high of more than 25,000 new Covid-19 infections, as authorities sought to get the city moving again after more than two weeks.

Pressure has been building on authorities in the country’s most populous city, and one of its wealthiest, from residents growing increasingly frustrated as the curbs dragged on, leaving some struggling to find enough food and medicine. Footage circulating online showed people screaming from their balconies, with the person filming claiming it was because people had grown tired of China’s strict lockdown rules.

Shanghai to ease lockdown despite surge in Covid cases ► https://www.theguardian.com/world/2022/apr/11/shanghai-to-ea…ovid-cases.

The Guardian publishes independent journalism, made possible by supporters. Contribute to The Guardian today ► https://bit.ly/3uhA7zg.

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Mojo Vision’s New Contact Lens Brings Seamless Augmented Reality a Step Closer

Around the rim of the lens is an array of other electronics, including a custom-designed chip with a radio that streams content to the display and a variety of sensors, including an accelerometer, gyroscope, and magnetometer for tracking the user’s eye movements. This eye tracking capability not only ensures that AR imagery holds still as the user looks around, but also makes it possible to control the device through eye movements alone.

Despite their efforts to pack as much into the lens as possible, it won’t be a stand-alone piece of equipment. Most of the computing power required to run AR applications will be contained in a companion device worn around the neck, which will stream the content to the lens wirelessly.

The lens also hasn’t yet been cleared by the FDA for human use, so early demonstrations involve looking through a lens on a stick just in front of the eye. At present it is only capable of producing images in a green monochrome. But according to CNET , the device allows a user to select a variety of apps arranged in a ring around the periphery of their field of vision using nothing more than their gaze. These make it possible to do everything from checking flight information to using a compass to navigate and track fitness data like heart rate and lap number.

What Your Blood Type Means For Heart Health, According to Science

People with type O-blood are considered “universal donors” because their blood doesn’t have any antigens or proteins, meaning anybody’s body will be able to accept it in an emergency.

But why are there different blood types? Researchers don’t fully know, but factors such as where someone’s ancestors are from and past infections which spurred protective mutations in the blood may have contributed to the diversity, according to Dr. Douglas Guggenheim, a hematologist with Penn Medicine. People with type O blood may get sicker with cholera, for example, while people with type A or B blood may be more likely to experience blood clotting issues. While our blood can’t keep up with the different biological or viral threats going around in real time, it may reflect what’s happened in the past.

“In short, it’s almost like the body has evolved around its environment in order to protect it as best as possible,” Guggenheim says.

These upcoming cancer vaccines may prevent tumors before they appear

Therapies designed to increase T cell’s killing power and ability to target cancer after it appears have already been approved, and they can be quite successful at treating some cancers. (More recent work is recruiting another type of immune cell, the awesomely named natural killer cells, to fight cancer.)

Vaccines that prevent cancer caused by viruses, like hepatitis B and HPV, already exist, but the vast majority of cancers have other causes — inherited mutations, external causes (like smoking or UV exposure), or just random bad luck.

A vaccine against cancers caused by Lynch syndrome — an inherited disorder — will be among the first to test if a vaccine can stop nonviral cancers from appearing. The Lynch trial is among several looking to test a new generation of preventative cancer vaccines.

AGE Products Impact Lifespan: Impact Of Hyperglycemia, Kidney Function, And The Microbiome

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Papers referenced in the video:
Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan.
https://pubmed.ncbi.nlm.nih.gov/18599606/

Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression.
https://pubmed.ncbi.nlm.nih.gov/17525257/

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N 6-carboxymethyllysine.
https://pubmed.ncbi.nlm.nih.gov/35241804/

Plasma Carboxymethyl-Lysine, an Advanced Glycation End Product, and All-Cause and Cardiovascular Disease Mortality in Older Community-Dwelling Adults.
https://pubmed.ncbi.nlm.nih.gov/19682127/

Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community dwelling women.

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Nanoclusters self-organize into centimeter-scale hierarchical assemblies

Nature may abhor a vacuum, but it sure loves structure. Complex, self-organized assemblies are found throughout the natural world, from double-helix DNA molecules to the photonic crystals that make butterfly wings so colorful and iridescent.

A Cornell-led project has created synthetic nanoclusters that can mimic this hierarchical self-assembly all the way from the nanometer to the centimeter scale, spanning seven orders of magnitude. The resulting synthetic thin films have the potential to serve as a model system for exploring biomimetic hierarchical systems and future advanced functions.

This image shows synthetic nanoparticles as they self-organize into filaments, then twist into cables, then bundle together into highly ordered bands, ultimately resulting in a thin film that is patterned at centimeter scales. (Image courtesy of the researchers)

Scientists Develop a Technology That Reverses Hearing Loss

Founded by MIT scientists, the clinical-stage biotech company Frequency Therapeutics discovered a way to reverse hearing loss without hearing aids or implants. Focusing on progenitor cells (which reside in the inner ear and turn into hair cells when humans are in utero, before going dormant) the company injects small molecules into the cochlea, which transform these cells into hair cells that help us hear. During their 200-person trial, the company saw meaningful improvement in patients’ hearing, with some reporting improved speech perception after a single injection that lasted nearly two years. “I wouldn’t be surprised if, in 10 or 15 years, because of the resources being put into this space and the incredible science being done, we can get to the point where [reversing hearing loss] would be similar to Lasik surgery, where you’re in and out in an hour or two,” says Harvard-MIT Health Sciences and Technology affiliate faculty member Jeff Karp. While the drug still needs to undergo further testing, the breakthrough is a hopeful milestone for the field of regenerative medicine. Read more about it at SciTechDaily.

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