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New Pill Replicates Exercise and Strengthens Muscle

A drug has been identified by researchers at Tokyo Medical and Dental University (TMDU) that replicates the benefits of exercise on mice’s bones and muscles.

You can look and feel better by keeping up a regular exercise schedule, but did you know that exercise also supports bone and muscle health? Locomotor fragility, which affects people who are unable to exercise, causes the muscles and bones to deteriorate. Recently, Japanese researchers discovered a new drug that, by producing effects comparable to those of exercise, may help treat locomotor frailty.

Physical inactivity can result in a weakening of the muscles (known as sarcopenia) and bones (known as osteoporosis). Exercise dispels this frailty by boosting muscular strength and suppressing bone resorption while simultaneously promoting bone formation. Exercise therapy, however, cannot be used in every clinical situation. When patients have dementia, cerebrovascular disease, or are already bedridden, drug therapy may be very helpful for treating sarcopenia and osteoporosis. However, there is no one drug that targets both tissues at the same time.

A Potential Game Changer for Type 2 Diabetics — New Therapeutic Target Identified

A new discovery could be a game-changer for patients with type 2 diabetes. Researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai have discovered a therapeutic target for the preservation and regeneration of beta cells (β cells), the cells in the pancreas that produce and distribute insulin. The finding could also help millions of individuals throughout the globe by preventing insulin resistance. The study was recently published in the journal Nature Communications.

Nature Communications is a peer-reviewed, open access, multidisciplinary, scientific journal published by Nature Research. It covers the natural sciences, including physics, biology, chemistry, medicine, and earth sciences. It began publishing in 2010 and has editorial offices in London, Berlin, New York City, and Shanghai.

Adult Brain Structure Is Not Fixed: Scientists Discover Depression Treatment Increases Brain Connectivity

Most scientists believe that the structure of the adult brain is generally rigid and incapable of rapid changes. However, new research has now revealed that this is not true. In a new study, German scientists have shown that in-patient treatment for depression can lead to an increase in brain connectivity. Moreover, those individuals who respond well to this treatment show a greater increase in connectivity than those who don’t.

Presenting the work at the European College for Neuropsychopharmacology Congress in Vienna, lead researcher, Professor Jonathan Repple said:

“This means that the brain structure of patients with serious clinical depression is not as fixed as we thought, and we can improve brain structure within a short time frame, around 6 weeks. We found that if this treatment leads to an increase in brain connectivity, it is also effective in tackling depression symptoms. This gives hope to patients who believe nothing can change and they have to live with a disease forever, because it is “set in stone” in their brain.”

Will People Be Able To Regrow Organs?

Will humans be able to grow replacement organs? LyGenesis aims to prove it can be done.


LyGenesis is a biomedical company hoping to deliver a technology that will allow patients to grow functioning organs. If successful the company’s cell therapies will disrupt organ transplantation allowing patients to grow their own. Instead of surgery, a person will do what some amphibians and reptiles do today when they lose a limb or tail.

The company is using the inherent nature of lymph nodes and their evolutionary function, turning them into rapid bioreactors. Our lymph nodes already do this when they produce infection-fighting T-cells. But LyGenesis’ therapies turn donated organ cells into biofactories that can become a source for producing viable organs in multiple patients. The only minimally invasive procedure involved is the engrafting of the cells into a patient’s lymph nodes to begin the process of organ development.

IIT Madras collaborates with NASA JPL to study microbes aboard ISS

The Indian Institute of Technology (IIT) Madras has announced a collaborative study with the Jet Propulsion Laboratory (JPL), the research hub of central US space agency National Aeronautics and Space Administration (NASA), to study the impact of microorganisms aboard the International Space Station. Observations from the research project will help create medical solutions to aid astronauts in long term human missions in space.

Explaining the observations, Karthik Raman, assistant professor at the department of biotechnology, IIT Madras, said that the collection of microbes, which includes a variety of bacteria and fungi, have occurred over time due to the astronauts that have been aboard the ISS over the past decades.

“Even though the ISS is a highly sterile environment, these microbes can play a big role in the way human presence in a space environment works — which our research work sought to highlight,” Raman said.

Study: Cancer-causing gas leaking from CA stoves, pipes

Gas stoves in California homes are leaking cancer-causing benzene, researchers found in a new study published on Thursday, though they say more research is needed to understand how many homes have leaks.

In the study, published in Environmental Science and Technology on Thursday, researchers also estimated that over 4 tons of benzene per year are being leaked into the atmosphere from outdoor pipes that deliver the gas to buildings around California — the equivalent to the benzene emissions from nearly 60,000 vehicles. And those emissions are unaccounted for by the state.

The researchers collected samples of gas from 159 homes in different regions of California and measured to see what types of gases were being emitted into homes when stoves were off. They found that all of the samples they tested had hazardous air pollutants, like benzene, toluene, ethylbenzene and xylene (BTEX), all of which can have adverse health effects in humans with chronic exposure or acute exposure in larger amounts.

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