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Category: biotech/medical – Page 1,301

Turkish scientists develop ‘fiber sensor’ shoes for early diagnosis

A new technology that incorporates flexible fiber sensors into shoes has been developed by the National Nanotechnology Research Center (UNAM) at Bilkent University and is able to identify a number of health issues, including Parkinson’s disease and gait disorders.

Project manager Mustafa Ordu, who specialized in the production and characterization of fiber cables that can generate electricity for wearable devices, explained that the technology developed at UNAM is loaded with smart sensors that can monitor body movements and determine issues and diseases, with the potential to diagnose many health problems.

Further explaining the cutting-edge technology, he said that it can be woven into body wear or incorporated into footwear since by knitting these cables together like a type of threaded fabric, they can be incorporated into clothing as fibers. “This is what makes our team stand out among the existing laboratories in the world; we make smart sensors with flexible fiber and two-dimensional materials,” said Ordu.

Harvard Medical Researchers Discover Surprising Protective Properties of Pain

New research in mice illuminates how pain neurons shield the gut from damage.

Pain is one of evolution’s most effective mechanisms for detecting injury and letting us know that something is wrong. It acts as a warning system, telling us to stop and pay attention to our body.

But what if pain is more than just a mere alarm signal? What if pain is in itself a form of protection?

Your iPhone 14 May Call the Cops If You Ride a Rollercoaster

When Apple built crash detection into the iPhone 14, the company touted it as a life-saving feature. However, it’s causing some headaches for law enforcement, paramedics, and dispatchers who receive emergency calls informing them of a severe crash that never occurred.

According to The Wall Street Journal, a spate of these false positives have hit the Warren County Communications Center in Ohio since mid-September. In one such case, a King’s Island amusement park patron, 39-year-old Sarah White, rode the Mystic Timbers rollercoaster with her days-old iPhone 14 in her pocket. After the ride was over, her phone was flooded with notifications, missed calls, and voicemails from emergency services.

The iPhone registered the rollercoaster experience as a car crash and called 911, informing the police that “The owner of this iPhone was in a severe car crash and is not responding to their phone…” You can listen to the audio of the emergency call below.

Researchers Have a New Theory About What Causes Alzheimer’s, And It’s Not Plaque

In 1906, Alois Alzheimer, a psychiatrist and neuroanatomist, reported “a peculiar severe disease process of the cerebral cortex” to a gathering of psychiatrists in Tübingen, Germany.

The case was a 50-year-old woman who suffered from memory loss, delusions, hallucinations, aggression, and confusion – all of which worsened until her untimely death five years later.

In the autopsy, Alzheimer noticed distinctive plaques on her brain. These plaques – clumps of amyloid-beta protein – are still considered to be the cause of Alzheimer’s disease.

The Cholesterol-DHEA-S Experiment; A Role For Thyroid Function on DHEA-S And/Or Homocysteine?

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Scientists Uncover How to Reverse Aging

Scientists have successfully increased the lifespan of animals and there are first studies which describe how we might reverse aging. So how could we one day rever aging?

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In the 70s, scientists observed that cells only grow for a limited amount of days in the laboratory (Hayflick limit). Over the years, so-called hallmarks of aging have been uncovered. These hallmarks of aging govern how our cells age and we could try to slow dem down to “reverse aging”.
The first hallmark of aging is mutation. We can acquire mutations by being exposed to UV radiation or certain chemicals or through cell division. Cell divsion also leads to a second hallmark of aging (telomere attrition). Furthermore, our mitochondria start to work less as quality checks do not work properly anymore.
The hallmarks of aging are tightly linked to epigenetics. Epigenetics means that we have mechanisms (DNA methylation, histone modifications) which regulate the activity of genes. Epigenetics governs the development of embryonic stem cells into cells of our body but also impact aging. The loss of mitochondria for example is linked to dysfunctional epigenetic layers. As we age, at least three epigenetic modifications namely H4K16 acetylation, H3K4 trimethylation, or H4K20 trimethylation acumulate. The thing is that epigenetics is reversible… so can we also reverse aging?
Diets have been shown to slow down (and reverse aging to a small degree). Cells also show less damages in their DNA and we find higher levels of proteins which are found in “young cells. The activity of mitochondria is also increased if we undergo caloric restriction. Diets also impact the production of sirtuins which increase the lifespan and reverse aging. Different compounts (such as NMN and remodelin) have been shown to improve the epigenetic landscape which might have an effect on reversing aging. Exercise also might help to reverse aging as it helps to increase the activity of mitochondria. Meditation and having less stress also helps to increase the lengths of telomeres which might help to reverse aging. All in all studies suggests that some hallmarks of aging can be reversed so lets see where that goes!

0:00–0:46 Intro.
0:46–3:53 Hallmarks of Aging.
3:53–6:38 Epigenetics Controls Genes.
6:38–8:45 Reversing Aging: what is known.
8:45–11:25 Reversing Aging through Diets & Sports.
11:25–12:13 My Opinion.

References:

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