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Archive for the ‘biotech/medical’ category: Page 1296

Oct 4, 2020

DARPA’s SIGMA Program Transitions to Protect Major U.S. Metropolitan Region

Posted by in categories: biological, biotech/medical, chemistry, terrorism, transportation

On a blustery winter day last December, a car carrying radioactive material approached one of the Port Authority of New York and New Jersey’s major transportation hubs. As the car got closer, an alarm flashed and sounded on a large monitor in the police operations center, identifying on a digital map the exact location of the vehicle and the specific radioactive isotope radiating from the car – Cesium-137. Within minutes, officers in the Port Authority Police Department – equipped with vehicle-mounted and pocket-sized radiation sensors displaying the same real-time digital map – tracked the vehicle and apprehended the suspects in a parking lot. Thankfully, the potential terrorists and radiation-emitting isotope were not a threat, as the scenario was only a drill.

The December exercise marked the capstone for DARPA’s SIGMA program, culminating a five-year effort to develop and deploy an automated, high-performance, networked radiation detection capability for counterterrorism and continuous city-to-region scale radiological and nuclear threat monitoring. The transition of the radiation-detection system took place prior to the coronavirus disease (COVID-19) pandemic. In the eight months since the SIGMA transition, DARPA has been developing and testing additional sensors under its SIGMA+ effort to detect chemical, biological and explosive threats as well.

“We want to thank the Port Authority for their outstanding support throughout the SIGMA program and their continued support as we test SIGMA+ sensors,” said Mark Wrobel, DARPA program manager in the Defense Sciences Office. “Being able to test and refine the system in the country’s largest metropolitan region was invaluable in taking SIGMA from a research project to an operationally deployed system in just five years.”

Oct 4, 2020

A DARPA-Funded Implantable Biochip to Detect COVID-19 Could Hit Markets by 2021

Posted by in categories: biotech/medical, genetics, health

An experimental new vaccine claims to be able to change human DNA and could be deployed against COVID-19 by 2021 through a biochip implant.


The most significant scientific discovery since gravity has been hiding in plain sight for nearly a decade and its destructive potential to humanity is so enormous that the biggest war machine on the planet immediately deployed its vast resources to possess and control it, financing its research and development through agencies like the National Institutes of Health (NIH), the Defense Advanced Research Projects Agency (DARPA) and HHS’ BARDA.

The revolutionary breakthrough came to a Canadian scientist named Derek Rossi in 2010 purely by accident. The now-retired Harvard professor claimed in an interview with the National Post that he found a way to “reprogram” the molecules that carry the genetic instructions for cell development in the human body, not to mention all biological lifeforms.

Continue reading “A DARPA-Funded Implantable Biochip to Detect COVID-19 Could Hit Markets by 2021” »

Oct 4, 2020

New Method of 3D-Printing Soft Materials Could Jump-Start Creation of Tiny Medical Devices for the Body

Posted by in categories: 3D printing, biotech/medical

Researchers at the National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in a new paper, it has the potential to create complex structures with nanometer-scale precision. Because many gels are compatible with living cells, the new method could jump-start the production of soft tiny medical devices such as drug delivery systems or flexible electrodes that can be inserted into the human body.

A standard 3D printer makes solid structures by creating sheets of material — typically plastic or rubber — and building them up layer by layer, like a lasagna, until the entire object is created.

Using a 3D printer to fabricate an object made of gel is a “bit more of a delicate cooking process,” said NIST researcher Andrei Kolmakov. In the standard method, the 3D printer chamber is filled with a soup of long-chain polymers — long groups of molecules bonded together — dissolved in water. Then “spices” are added — special molecules that are sensitive to light. When light from the 3D printer activates those special molecules, they stitch together the chains of polymers so that they form a fluffy weblike structure. This scaffolding, still surrounded by liquid water, is the gel.

Oct 4, 2020

WHO’s Decade of Healthy Aging: Country Spotlight

Posted by in categories: biotech/medical, education, life extension, policy, transhumanism

TODAY (Oct 4th) the USTP is holding a special pre-RAADFest Enlightenment Salon at 7 a.m. PST / 10 am EST with Gabor Kiss, CEO of ENVIENTA, to discuss ways to empower contributors to open-source projects and accelerate development of practical transhumanist technologies.


Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Alexandre Kalache, President of the International Longevity Centre-Brazil (ILC-Brazil).

Continue reading “WHO’s Decade of Healthy Aging: Country Spotlight” »

Oct 3, 2020

Artificial Hearts 🖤: The Road To Future Humans

Posted by in categories: 3D printing, biotech/medical, transhumanism

Researchers in Israel have been able to 3D Print an artificial heart. Within the 2020s decade, we may see working versions implanted in humans.

What do you think about a future where we can 3D Print body organs & parts?

#Iconickelx #Transhumanism #Future

Oct 3, 2020

The Road to Human 2.0

Posted by in categories: 3D printing, biotech/medical, computing, genetics, life extension, nanotechnology, neuroscience, transhumanism

In the coming 2020s, the world of medical science will make some significant breakthroughs. Through brain implants, we will have the capability to restore lost memories.

~ The 2020s will provide us with the computer power to make the first complete human brain simulation. Exponential growth in computation and data will make it possible to form accurate models of every part of the human brain and its 100 billion neurons.

~ The prototype of the human heart was 3D printed in 2019. By the mid- 2020s, customized 3D- printing of major human body organs will become possible. In the coming decades, more and more of the 78 organs in the human body will become printable.

Continue reading “The Road to Human 2.0” »

Oct 3, 2020

Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells (DOI: 10.1016/j.medidd.2020.100044)

Posted by in category: biotech/medical

Oct 2, 2020

‘Young’ microbiota can reverse ageing of the immune system and boost vaccines

Posted by in categories: biotech/medical, life extension

Every human being is home to trillions of microbes that are collectively known as the microbiota. Recent research into how these microbes affect the immune system may explain why older people are more vulnerable to disease and suggest ways to tackle that vulnerability.

Scientists at The University of Edinburgh’s Roslin Institute, led by Professor Neil Mabbott, discovered that as mice get older they showed a marked decrease in the number of M cells found in the lining of the gut. These are specialised cells that look out for infections and trigger the early stages of the immune response. Fewer M cells means a weaker immune system. At the same time, the researchers found that the older mice had depleted microbiota compared to younger mice. The microbiota were less diverse and certain species known to decrease inflammation of the gut in humans were missing.

Oct 2, 2020

New nanotechology design provides hope for personalized vaccination for treating cancer

Posted by in categories: biotech/medical, chemistry, nanotechnology

One of the key challenges in developing effective, targeted cancer treatments is the heterogeneity of the cancer cells themselves. This variation makes it difficult for the immune system to recognize, respond to and actively fight against tumors. Now, however, new advances in nanotechnology are making it possible to deliver targeted, personalized “vaccines” to treat cancer.

A new study, published on October 2, 2020 in Science Advances, demonstrates the use of charged nanoscale metal-organic frameworks for generating free radicals using X-rays within tumor tissue to kill directly. Furthermore, the same frameworks can be used for delivering immune signaling molecules known as PAMPs to activate the immune response against . By combining these two approaches into one easily administered “vaccine,” this new technology may provide the key to better local and systemic treatment of difficult-to-treat cancers.

In a collaboration between the Lin Group in the University of Chicago Department of Chemistry and the Weichselbaum Lab at University of Chicago Medicine, the research team combined expertise from inorganic chemistry and to tackle the challenging problem of properly targeting and activating an innate immune response against . This work leveraged the unique properties of nanoscale metal-organic frameworks, or nMOFs —nanoscale structures built of repeating units in a lattice formation that are capable of infiltrating tumors.

Oct 2, 2020

Researchers discover a rare genetic form of dementia

Posted by in categories: biotech/medical, genetics, neuroscience

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain—which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer’s Disease—that could be targeted for new therapies. The study was published today in Science.

Alzheimer’s (AD) is a neurodegenerative disease characterized by a buildup of proteins, called , in certain parts of the brain. Following an examination of human brain tissue samples from a deceased donor with an unknown neurodegenerative disease, researchers discovered a novel mutation in the Valosin-containing protein (VCP) gene in the brain, a buildup of tau proteins in areas that were degenerating, and neurons with empty holes in them, called vacuoles. The team named the newly discovered disease Vacuolar Tauopathy (VT)—a neurodegenerative disease now characterized by the accumulation of neuronal vacuoles and tau protein aggregates.

“Within a cell, you have proteins coming together, and you need a process to also be able to pull them apart, because otherwise everything kind of gets gummed up and doesn’t work. VCP is often involved in those cases where it finds proteins in an aggregate and pulls them apart,” Edward Lee, MD, Ph.D., an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. “We think that the mutation impairs the proteins’ normal ability to break aggregates apart.”