Summary: Researchers develop a novel tool that allows for the study of the communication of microbes in the gastrointestinal tract and the brain.
Source: Baylor College of Medicine.
In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gutโbrain axis.
๐๐ซ๐๐๐ค๐ญ๐ก๐ซ๐จ๐ฎ๐ ๐ก!
๐๐๐ฎ๐ซ๐จ๐ฌ๐๐ข๐๐ง๐ญ๐ข๐ฌ๐ญ๐ฌ ๐ฌ๐จ๐ฅ๐ฏ๐ ๐ฆ๐ฒ๐ฌ๐ญ๐๐ซ๐ข๐๐ฌ ๐๐๐จ๐ฎ๐ญ ๐ฅ๐๐๐๐ข๐ง๐ ๐๐ข๐จ๐ฆ๐๐ซ๐ค๐๐ซ ๐๐จ๐ซ ๐๐ฅ๐ณ๐ก๐๐ข๐ฆ๐๐ซโ๐ฌ
๐๐ฃ๐๐ซ๐๐ง๐จ๐๐ฉ๐ฎ ๐ค๐ ๐๐๐ง๐๐๐ฃ๐๐ ๐ฃ๐๐ช๐ง๐ค๐จ๐๐๐๐ฃ๐ฉ๐๐จ๐ฉ๐จ ๐๐๐ซ๐ ๐ง๐๐ซ๐๐๐ก๐๐ ๐๐ค๐ฌ ๐ ๐ฉ๐ค๐ญ๐๐ ๐๐ค๐ง๐ข ๐ค๐ ๐ฉ๐๐ช ๐ฅ๐ง๐ค๐ฉ๐๐๐ฃ, ๐ฃ๐ค๐ฉ๐ค๐ง๐๐ค๐ช๐จ ๐๐ค๐ง ๐๐ค๐ง๐ข๐๐ฃ๐ ๐ฉ๐๐ฃ๐๐ก๐๐จ ๐๐ฃ ๐ฉ๐๐ ๐๐ง๐๐๐ฃ๐จ ๐ค๐ ๐ฅ๐๐ค๐ฅ๐ก๐ ๐ฌ๐๐ฉ๐ ๐ผ๐ก๐ฏ๐๐๐๐ข๐๐งโ๐จ ๐๐๐จ๐๐๐จ๐ ๐๐ฃ๐ ๐จ๐๐ซ๐๐ง๐๐ก ๐ค๐ฉ๐๐๐ง ๐ฃ๐๐ช๐ง๐ค๐๐๐๐๐ฃ๐๐ง๐๐ฉ๐๐ซ๐ ๐๐๐จ๐ค๐ง๐๐๐ง๐จ, ๐จ๐ฅ๐ง๐๐๐๐จ ๐ฉ๐๐ง๐ค๐ช๐๐ ๐ฉ๐๐ ๐๐ง๐๐๐ฃ ๐๐จ ๐ฉ๐๐ ๐๐๐จ๐๐๐จ๐ ๐ฅ๐ง๐ค๐๐ง๐๐จ๐จ๐๐จ.
The new discovery advances the battle against the disease, which strikes 1 in 9 people over age 65.
A SpaceX Cargo Dragon 2 spacecraft has safely returned to Earth after delivering several tons of NASA supplies to the International Space Station (ISS).
A little over six weeks after Falcon 9 launched SpaceXโs 26th Commercial Resupply Services 2 (CRS2) mission for NASA, Dragon departed the ISS on January 9th. Efficiently lowering its orbit with several small Draco thrusters took about 36 hours, and reusable Dragon 2 capsule C211 eventually slowed to the point that it began impacting Earthโs atmosphere. Using its ablative heat shield like a brake pad, Dragon slowed from a velocity of 7.5 kilometers per second (16,800 mph) to about 155 meters per second (~350 mph) before beginning parachute deployment.
At 5:19 am on January 11th, the Dragon capsule gently splashed down off the coast of Tampa, Florida, and was quickly secured by a SpaceX recovery ship. Once onboard, the capsule was opened up, and cargo fresh from orbit was loaded onto a helicopter as quickly as possible. That system โ primarily created to rapidly transport astronauts back to NASA medical facilities โ also means that scientists can get access to their recovered ISS experiments just a handful of hours after Cargo Dragon splashes down.
This might be important. It might not be over for metformin just yet though as a mice study showed that rapamycin combined with metformin removed each otherโs side effects.
If you are a non-diabetic who takes metformin for longevity, I highly recommend you stop immediately. Hear me out, and at the end of the video Iโll share what to do instead.
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We flew to the UK to learn more about the designer 3D-printing third thumbs. Is this the dawn of human body augmentation?
Watch the Hard Reset series โบ https://www.youtube.com/playlist?list=PLXthoedLVIdLvnNgiCshQvqKdS7T_qeGY
Motorized prosthetics are nothing new. But what about artificial body parts that donโt replace missing ones, but instead provide us with extended capabilities, while also revealing insights into the relationship between brain and body?
Thatโs the main research focus of augmentation designer Dani Clode, who developed the Third Thumb, a 3D-printed extension for your hand that is controlled by your toes.
Through collaborative neuroscientific research with The Plasticity Lab at University College London & Cambridge University, Clode and her colleagues hope to better understand how the brain adapts to augmentation, learn more about the limits of neuroplasticity, and explore how to best utilize it to improve the control and usability of prosthetics and augmentative devices.
Watch on Freethink.com โบ https://www.freethink.com/series/hard-reset/bionic-third-thumb.
Scientists at the University of Cambridge have successfully trialed an artificial pancreas for use by patients living with type 2 diabetes. The device โ powered by an algorithm developed at the University of Cambridge โ doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time spent experiencing high glucose levels.
Around 415 million people worldwide are estimated to be living with type 2 diabetes, which costs around $760 billion in annual global health expenditure. According to Diabetes UK, more than 4.9 million people have diabetes in the UK alone, of whom 90% have type 2 diabetes, and this is estimated to cost the NHS ยฃ10 billion per year.
โMany people with type 2 diabetes struggle to manage their blood sugar levels using the currently available treatments, such as insulin injections. The artificial pancreas can provide a safe and effective approach to help them, and the technology is simple to use and can be implemented safely at home.โ โ
San Diego-based biotech startup Rejuvenate Bio is making a major claim thatโll likely draw heated scrutiny from the scientific community: that its technology was able to significantly extend the lives of elderly mice.
According to a yet-to-be-peer-reviewed paper, scientists at the company say an injection that reprograms genes in the bodies of senior mice effectively doubled their remaining life span, MIT Technology Review reports.
In tests, the company found that treated mice lived on for another 18 weeks on average. Those who were not treated in a control group only lived for another nine weeks. Overall, they say, the gene hacked mice lived roughly seven percent longer overall.
Scientists from The Australian National University (ANU) and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.
One of the hallmarks of cancer is that the normal regulation of genes is disrupted, and this causes cancer cells to look and behave differently to normal cells. Cancer cells can switch off certain genes, keeping them in a dormant state. By deactivating specific immune genes, some cancers are able to evade detection by the immune system, essentially becoming invisible. This allows the cancer to grow and become more aggressive.
By targeting the Menin protein using drug therapies, the researchers believe they can reactivate these genes, making the cancer cells once again visible and allowing the immune system to seek out and destroy them.
Biorealistic organic electrochemical neurons enabled by ion-tunable antiambipolarity in mixed ion-electron conducting polymers.
An artificial organic neuron that closely mimics the characteristics of biological nerve cells has been created by researchers at Linkรถping University (LiU), Sweden. This artificial neuron can stimulate natural nerves, making it a promising technology for various medical treatments in the future.
Work to develop increasingly functional artificial nerve cells continues at the Laboratory for Organic Electronics, LOE. In 2022, a team of scientists led by associate professor Simone Fabiano demonstrated how an artificial organic neuron could be integrated into a living carnivorous plant to control the opening and closing of its maw. This synthetic nerve cell met 2 of the 20 characteristics that differentiate it from a biological nerve cell.
Fungi such as Aspergillus are so common in our surroundings that we breathe in hundreds to thousands of spores every day. In healthy people, fungi typically pose no threat, but they can cause deadly infections in those with compromised immune systems. However, it is increasingly recognized that viral infections such as influenza or SARS-CoV-2 can increase the risk of invasive Aspergillus infections even in healthy people.
The World Health Organization (WHO) has stated that invasive fungal infections are an increasing threat to human health and has reiterated that more research is needed. Until now little was known about how the Aspergillus fungus was able to take root, and what could be done to get rid of it. Researchers at the University of Calgary working with researchers at McGill University have provided new insight on why the immune system fails.
โWe discovered that influenza and COVID-19 destroy a previously unknown natural immunity that we need to resist invasive fungal infections,โ says Nicole Sarden, a Ph.D. candidate at the University of Calgary and first author on the study.