Before the first clinical symptoms appear, Alzheimer’s.
Alzheimer’s disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimer’s disease, but there are medications that can help ease the symptoms.
The findings also point to possible directions for treatment of the disease.
The results are published Sept. 6 in the journal Neuron.
Almost half the human genome is comprised of transposable elements, long and short stretches of DNA called “jumping genes” for their ability to move from one location of the genome to others. Once called “junk” DNA, these transposable sequences have been shown to play crucial regulatory roles in many biological functions. Once they fulfill these myriad roles, molecular regulators usually silence their expression.
Along the way, they discuss the early days of David’s HedWeb, the Abolitionist Project, the Three Supers of Transhumanism (Superhappiness, Superintelligence, and Superlongevity), philosophy and history of science, the nature of intelligence, field theories of consciousness, anesthesia, empathogens, anti-tolerance drugs, and much more.
Some of the key essays discussed:
Utopian Pharmacology — “Mental Health in the Third Millennium — MDMA and Beyond” — https://mdma.net/
Future Opioids: The Quest for a Drug-Free Society — https://www.opioids.com/
The Biointelligence Explosion — “How recursively self-improving organic robots will modify their own source code and bootstrap our way to full-spectrum superintelligence” — https://www.biointelligence-explosion.com/
Research into how the blood protein vitronectin changes when under pressure – such as when it passes through the blood vessels at the back of the eye – could unlock the mechanism of macular degeneration.
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You’re on the PRO Robots channel, and today we’re bringing you some high-tech news. Robots from Boston Dynamics will get advanced artificial intelligence, neural networks will be able to translate the language of all animals, incredibly fast nanorobots will travel inside the human body, a robot-surgeon will perform an operation on the ISS. See these and other technology news in one video right now!
0:00 Intro.
0:28 Robots from Boston Dynamics get advanced artificial intelligence.
1:52 AI will never be intelligent.
2:50 Earth Species Project hopes to develop a neural network that can decipher animal language.
3:16 Species Project decides to go around and create an algorithm.
4:07 A gadget to control your smart home with your mind.
5:04 Nanobots.
5:19 The world’s fastest bowel robot.
6:10 Robots will join the U.S. space forces.
6:47 Surgical robot to be tested on ISS
7:37 GITAI News.
7:59 The first launch in NASA’s Artemis lunar mission.
8:34 Super Heavy rocket successfully passes first static firing test.
8:57 Gigafactory in Canada.
9:22 Baidu says its Jidu robot car autopilot will be a generation ahead of Tesla’s autopilot.
10:02 A system that can calculate the optimal end design and calculate the best trajectory for grabbing objects of any shape.
10:25 A drone to search for gold and jewelry.
11:22 Engineers have trained a drone with 12 rotary screws to manipulate objects.
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Research led by Sanford Burnham Prebys professor Francesca Marassi, Ph.D., is helping to reveal the molecular secrets of macular degeneration, which causes almost 90% of all age-related vision loss.
The study, published recently in the Biophysical Journal, describes the flexible structure of a key blood protein involved in macular degeneration and other age-related diseases, such as Alzheimer’s and atherosclerosis.
“Proteins in the blood are under constant and changing pressure because of the different ways blood flows throughout the body,” says Marassi. “For example, blood flows more slowly through small blood vessels in the eyes compared to larger arteries around the heart. Blood proteins need to be able to respond to these changes, and this study gives us fundamental truths about how they adapt to their environment, which is critical to targeting those proteins for future treatments.”
Researchers in China show that a technique used to replace diseased mitochondria does not affect early development.
Researchers are working on an injectable that could get dormant follicles growing again. Trials on mice show promise.
Scientists at McMaster University have identified a toxin used by bacteria to kill other bacteria through a never-before-seen mechanism. The toxin is the first found to directly target RNA molecules in what the team describes as “a total assault on the cell,” which could lead to a new class of antibiotics.
There’s a huge war raging on the microscopic scale as microbes battle each other for resources, and sometimes the weapons they use against each other can prove useful for antibiotics. Most of these toxins target proteins or DNA molecules, killing bacteria by interrupting vital functions.
So that’s the checklist that the team ran through while studying a toxin called RhsP2 that’s produced by Pseudomonas aeruginosa, a common bug behind hospital-acquired infections like pneumonia. Over three years, the researchers investigated the effects of the toxin on these common targets, to no avail.
