Dr Gabrielle Lyon is a functional medicine physician and Founder of the Institute of Muscle-Centric Medicine. Most health advice focuses on shedding excess weight. But what if your longevity, healthspan, resilience and quality of life was more determined by gaining muscle than losing fat? This isn’t a bodybuilder’s coping strategy, it’s new science backed by mountains of data. Expect to learn why the quality of your life is a direct correlation to your muscle health, whether it’s more dangerous to be over-fat or under-muscled, whether exercise is more important than nutrition, Gabrielle’s favourite hacks for getting more protein in every day, whether protein timing matters, if it’s possible to achieve this with a plant-based diet and much more…
Category: biotech/medical – Page 1,193
Breakthrough: Artificial DNA opens door to designer proteins
RNA polymerase
The key lies in mimicking nature’s machinery. The researchers identified RNA polymerase, a key enzyme that converts DNA into RNA, which is then used to make proteins. They designed two artificial nucleotides that flawlessly mimic the geometry of natural nucleotides. RNA polymerase readily accepted these novel additions when tested, seamlessly incorporating them into transcription.
Finding Balance in the Age of Indulgence
Anna Lembke is professor of psychiatry at Stanford University School of Medicine and chief of the Stanford Addiction Medicine Dual Diagnosis Clinic. A clinician scholar, she has published more than a hundred peer-reviewed papers, book chapters, and commentaries.
Controlling Addiction & Dopamine: A Practical Guide
Psychiatrist and author Dr. Anna Lembke discusses dopamine, addictive behaviors, warning signs and treatment for addiction, and how our brains handle all that pleasure and pain in life. Dr. Lembke is a professor of psychiatry at Stanford University School of Medicine and chief of the Stanford Addiction Medicine Dual Diagnosis Clinic. She appeared in the 2020 Netflix documentary The Social Dilemma to discuss the addictive nature of social media, and she is the author of the 2021 New York Times bestseller Dopamine Nation: Finding Balance in the Age of Indulgence, which explores how to moderate compulsive overconsumption in a dopamine-overloaded world.
Beyond Consciousness: How Meditators Voluntarily Enter Void States
Summary: Experienced meditators can voluntarily induce unconscious states, known as cessations, without the use of drugs. This ability, observed in Tibetan Buddhist practice, allows meditators to experience a momentary void of consciousness, followed by enhanced mental clarity.
Conducted across multiple countries, the study utilized EEG spectral analysis to objectively measure brain activity during these cessation events. By correlating the meditator’s first-person experience with neuroimaging data, researchers have gained insights into the profound modulation of consciousness achievable through advanced meditation practices.
Avoiding The Age-Related Increase For Blood Pressure
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Unstable ‘fluttering’ predicts aortic aneurysm with 98% accuracy
Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.
In the new study, the researchers forecasted abnormal aortic growth by measuring subtle “fluttering” in a patient’s blood vessel. As blood flows through the aorta, it can cause the vessel wall to flutter, similar to how a banner ripples in the breeze. While stable flow predicts normal, natural growth, unstable flutter is highly predictive of future abnormal growth and potential rupture, the researchers found.
Called the “flutter instability parameter” (FIP), the new metric predicted future aneurysm with 98% accuracy on average three years after the FIP was first measured. To calculate a personalized FIP, patients only need a single 4D flow magnetic resonance imaging (MRI) scan.
Fungus-fighting Protein could help Overcome Severe Autoimmune disease and Cancer
A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found.
The discovery could pave the way for new and more effective drugs, without the nasty side effects of existing treatments. In addition to helping to manage severe autoimmune conditions, the breakthrough could also help treat all types of cancer. The work has been published in Science Advances.
The scientists have discovered a previously unknown function of the protein, known as DECTIN-1, which in its mutated state limits the production of T regulatory cells or so-called ‘guardian’ cells in the immune system.
Vertex’s First Crispr Gene Editing Therapy Gets EU Backing
Europe’s health regulator followed the US and UK in backing the first gene-editing therapy to use Crispr technology, a Vertex Pharmaceuticals Inc. and Crispr Therapeutics AG treatment for sickle cell disease.
The European Medicines Agency’s expert panel recommended on Friday authorizing the Vertex and Crispr drug, Casgevy, for people with severe sickle cell disease and another serious hereditary blood disorder, beta-thalassemia, which is traditionally treated with repeated transfusions. Vertex said before the ruling that it had yet to establish a European list price for the one-time therapy, which costs $2.2 million in the US.
The treatment makes precisely targeted changes in patients’ DNA, a months-long process that requires removing bone marrow and a stem cell transplant. In Europe, Vertex said its initial focus will be on countries with the highest numbers of patients, including France, Italy, the UK and Germany.