Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1,051

Could knowing where your ancestors came from be the key to better cancer treatments? Maybe, but where would that key fit? How can we trace cancer’s ancestral roots to modern-day solutions? For Cold Spring Harbor Laboratory (CSHL) Research Professor Alexander Krasnitz, the answers may lie deep within vast databases and hospital archives containing hundreds of thousands of tumor samples.

Krasnitz and CSHL Postdoctoral Fellow Pascal Belleau are working to reveal the genealogical connections between and race or ethnicity. They’ve developed new software that accurately infers continental from tumor DNA and RNA. Their latest study is published in Cancer Research, and their work may help clinicians develop new strategies for early cancer detection and personalized treatments.

“Why do people of different races and ethnicities get sick at different rates with different types of cancer? They have different habits, living conditions, exposures—all kinds of social and . But there may be a as well,” Krasnitz says.

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The whole interview is good and informative but starts with Sinclair commenting that at the moment he thinks living to 150 is possible in our lifetimes but not immortality. But given that, I’m 51. If I’m going to live potentially another century the technology will get better and better in that century and I would fully expect to life spans to become what we want rather than what we have to accept.

In this Ask Me Anything session, David and Peter discuss the latest age-reversal breakthroughs, getting approval from the FDA, and the possibility of living forever.
David Sinclair is a biologist and academic known for his expertise in aging and epigenetics. Sinclair is a genetics professor and the Co-Director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research. He’s been included in Time100 as one of the 100 Most Influential People in the World, and his research has been featured all over the media. Besides writing a New York Times Best Seller, David has co-founded several biotech companies, a science publication called Aging, and is an inventor of 35 patents.
Read David’s book, Lifespan: Why We Age-and Why We Don’t Have To: https://a.co/d/85H3Mll.

This episode is brought to you by Levels: real-time feedback on how diet impacts your health. https://levels.link/peter.

Consider a journey to optimize your mind and body by visiting http://mylifeforce.com/peter.

Read the Tech Blog: https://www.diamandis.com/blog.

Continue reading “David Sinclair’s AMA: Age Reversal Breakthroughs, FDA Approval, and Living Forever” | >

The Covid omicron XBB.1.5 variant is rapidly becoming dominant in the U.S. because it is highly immune evasive and appears more effective at binding to cells than related subvariants, scientists say.

XBB.1.5 now represents about 41% of new cases nationwide in the U.S., nearly doubling in prevalence over the past week, according to the data published Friday by the Centers for Disease Control and Prevention. The subvariant more than doubled as a share of cases every week through Dec. 24. In the past week, it nearly doubled from 21.7% prevalence.

Scientists and public health officials have been closely monitoring the XBB subvariant family for months because the strains have many mutations that could render the Covid-19 vaccines, including the omicron boosters, less effective and cause even more breakthrough infections.

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A Peninsula biotech startup cofounded by pioneering geneticist George Church — who already is working to engineer the woolly mammoth out of extinction — is trying to raise as much as $5 million in a crowdfunding effort to design healthier, longer-living pets.

AdoraPet Biosciences Inc. of San Mateo plans to apply the genome-engineering CRISPR technology at the egg stage of dogs and cats or insert CRISPR-modified DNA into eggs, to make nonallergenic pets that don’t shed and ultimately live longer, are free of genetic diseases caused by inbreeding and are resistant to cancer and other serious diseases.

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Lung cancer is the third most common cancer in the United States, following skin and breast cancers– with over two hundred and thirty-six thousand cases diagnosed in 2022 alone, according to the American Cancer Society. The most significant risk factor includes smoking, with eighty to ninety percent of all lung cancer deaths being linked to smoking in the U.S. Other contributing factors include secondhand smoke, the inhalation of radon– a naturally occurring gas– and familial history of lung cancer.

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Leprosy is a chronic infectious disease caused by the bacterium Mycobacterium leprae. It affects the skin, nerves, and mucous membranes, and can lead to severe disfigurement and disability if left untreated.

Leprosy, a chronic infectious disease caused by the bacterium Mycobacterium leprae, is one of the oldest and most persistent diseases in the world. However, new surprising research suggests that the bacteria that cause leprosy may also have the ability to stimulate the growth and regeneration of the liver in adult animals without causing damage or scarring. Scientists have discovered that parasites associated with leprosy can reprogram cells to increase the size of the liver.

The findings suggest the potential to use this natural process to rejuvenate aging livers and extend the period of disease-free living in humans, known as healthspan. It may also be possible to use this process to regenerate damaged livers, potentially reducing the need for liver transplantation, which is currently the only effective treatment for individuals with severely scarred livers.

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Nobel winner Jennifer Doudna explains CRISPR, the gene-editing technology she pioneered.

Berkeley scientist Jennifer Doudna won the 2020 Nobel Prize for her work on the revolutionary gene-editing technology known as CRISPR. It has the potential to cure genetic diseases like sickle cell anemia and hereditary blindness and may even be used to treat cancer and HIV. But when it comes to editing humanity, where do we draw the line? How do we avoid falling into the same kind of dystopian nightmare outlined in Blade Runner? Doudna discussed the risks and benefits of CRISPR in an interview with Ian Bremmer on GZERO World. Also in this episode: a look at cloning our pets (speaking of going too far…).

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Continue reading “Applying CRISPR Tech to Edit the Code of Life | Dr. Jennifer Doudna | GZERO World with Ian Bremmer” | >