Premium Robots: https://taimine.com/ Deep Learning AI Specialization: https://imp.i384100.net/GET-STARTED A new multimodal artificial intelligence model from Microsoft called Kosmos-1 is able to process both text and visual data to the point of passing a visual IQ test with 26 percent accuracy, and researchers say this is a step towards AGI. Stable Diffusion AI can now read brain waves to reconstruct images that people are thinking about. Stanford has created a world record brain computer interface device with the help of AI to allow patients to type 62 words per minute with their thoughts.
AI News Timestamps: 0:00 Microsoft Kosmos-1 AI & AGI 3:34 AI Neuroscience Tech Reads Brain Waves. 5:43 AI & BCI Breaks Record.
Forget about He Jiankui, the Chinese scientist who created gene-edited babies. Instead, when you think about gene editing you should think of Victoria Gray, the African-American woman who says she’s been cured of her sickle-cell disease symptoms.
This week in London, scientists are gathering for the Third International Summit on Human Genome Editing. It’s gene editing’s big event, where researchers get to awe the audience with their new ability to modify DNA—and ethicists get to worry about what it all means.
Brave new world let’s create happiness for everyone by putting microelectrode arrays in our brains but be careful not to create a situation like death by ecstacy by Larry Niven.
In the brain, pleasure is generated by a handful of brain regions called, “hedonic hotspots.” If you were to stimulate these regions directly, you would likely feel pleasurable sensations. However, not all of the hedonic hotspots are the same–some generate the raw sensations of pleasure whereas others are responsible for consciously interpreting and elaborating on the raw pleasure produced by the other hotspots. In this video, in addition to exploring the neuroscience of pleasure, we’ll see how understanding pleasure, happiness, meaning, and purpose can help us live better lives.
- Chapters. 00:00 Hedonic hotspots: the brain’s pleasure generators. 00:56 The evolution of pleasure. 01:46 How the brain generates pleasure. 03:07 The subcortical (‘core’) pleasure network. 04:08 The cortical (‘higher’) pleasure network. 05:09 The orbitofrontal cortex’ role and the abstract to concrete pleasure gradient. 08:13 How to be happier by understanding the neuroscience of pleasure. 11:40 Summary.
Scientists Believe, ‘Organoid Intelligence’, Is the Future of Computing. CNN reports that as part of a new field called “organoid intelligence,” a computer powered by human brain cells could shape the future. Organoids are lab-grown tissues capable of brain-like functions, such as forming a network of connections. Brain organoids were first grown in 2012 by Dr. Thomas Hartung, a professor of environmental health and engineering, by altering human skin samples. Brain organoids were first grown in 2012 by Dr. Thomas Hartung, a professor of environmental health and engineering, by altering human skin samples. Computing and artificial intelligence have been driving the technology revolution but they are reaching a ceiling., Dr.
Dedicated to ending the HIV epidemic — dr. moupali das, MD, MPH, executive director, HIV clinical research, gilead sciences.
Dr. Moupali Das, MD, MPH, is Executive Director, HIV Clinical Research, in the Virology Therapeutic Area, at Gilead Sciences (https://www.gilead.com/), where she leads the pre-exposure prophylaxis (PrEP) clinical drug development program, including evaluating the safety and efficacy of a long-acting, twice yearly, subcutaneous injection being studied for HIV prevention. Her responsibilities also include expanding the populations who may benefit from PrEP.
Dr. Das has led high-performing teams in academic medicine, public health, implementation science, and cross-functionally in drug development. She has successfully helped develop, implement, and evaluate how to better test, link to care, increase virologic suppression, and improve quality of life for people with HIV, and to prevent HIV in those who may benefit from PrEP.
During the COVID19 pandemic, Dr. Das assisted her colleagues in the COVID-19 treatment program, leading the evaluation of a COVID-19 treatment for use in pregnant women and children from the compassionate use program.
After completing her undergraduate degree in Biochemical Sciences at Harvard College, medical school and internal medicine residency training at Columbia University and New York Presbyterian Hospital, Dr. Das came to University of California, San Francisco (UCSF) for fellowship training in Infectious Diseases and to University of California, Berkeley for her MPH in Epidemiology. She cared for HIV patients at San Francisco General’s storied Ward 86 clinic and attended on the inpatient ID Consult Service. She is recognized internally and externally for her expertise in epidemiology, public health, advocacy, and community engagement.
National University of Singapore (NUS) pharmaceutical scientists have developed synthetic peptide nanonets for treating infections by bacteria strains resistant to last-resort antibiotics.
In nature, trap-and-kill is a common immune defense mechanism employed by various species, including humans. In response to the presence of pathogens, peptides are released from host cells and they promptly self-assemble in solution to form cross-linked nanonets, which then entrap the bacteria and render them more vulnerable to antimicrobial components.
Several research groups have explored synthetic biomimetics of nanonets as an avenue for addressing the global healthcare challenge of widespread antibiotic resistance. However, most prominent studies in the field only yielded disjointed short nanofibrils restricted to the bacterial surfaces and are incapable of physically immobilizing the bacteria. Additionally, these designs were lacking in control over the initiation of the self-assembly process.
Biophysical Therapeutics, a drug discovery platform company that leverages computational biology, has emerged from stealth. The primary targets of the Delaware-based company are cancer, the diseases of aging (including Alzheimer’s disease) and – excitingly – aging itself.
Founded by Dr Michael Forrest, a Cambridge University biochemistry graduate with a PhD in computer science, Biophysical Therapeutics boasts renowned biotech entrepreneur Professor George Church (of Harvard Medical School) as an advisor to the company. Professor Bruno Conti of the Scripps Institute in La Jolla, California is also an advisor.
Longevity. Technology: Back in 2006, Conti and his team reported an exciting result in the prestigious journal Science. They showed (in female mice) that slightly reducing the metabolic rate by slightly reducing metabolic heat generation (decreasing body temperature by 0.34°C) increased lifespan by 20%.
In this Ask Me Anything interview, Prof. Matt Kaeberlein discusses the evidence (and lack thereof) behind popular anti-aging supplements and interventions. Starting from his current research on rapamycin for healthy longevity in dogs (The Dog Aging Project), he describes the promises and perils of anti-aging medicine and shares with us some tips on how to become better critical thinkers and protect us from hype and snake oil.
This interview is a must watch for everyone who wants to develop a critical stance toward the field of longevity research and balance enthusiasm with evidence.
I hope you enjoy this interview!
TIMESTAMPS 00:00 Introduction. 04:33 Definitions: Aging, lifespan, healthspan. 09:08 What is biohacking. 14:56 The Dog Aging project. 19:39 Rapamycin: Longevity effects in mice. 22:28 Can rapamycin impair muscle growth? Is it in contraindicated for people who want to build muscle mass? 27:09 Exercise, inhibition of mTor, and rationale for cycling rapamycin and exercise. 29:46 Getting around the growth vs. resilience tradeoff in longevity. 32:00 Epigenetic clocks: Hope vs. hype. 32:43 Best functional markers of longevity. 36:30 Sterile inflammation, auto-immunity, and immune senescence. 40:24 The best and worst longevity supplements for Matt Kaeberlein. 45:50 What longevity hacks Matt implements in his own life. 48:00 Lucia’s and Matt’s thoughts on calorie restriction for longevity. 50:30 How can people discriminate between science and sneak oil?
Because it CAN be done does not mean it SHOULD be done.
We humans have not yet developed a strong understanding of unintended consequences.
Human neurons can survive — and even develop — after being transplanted into newborn rats. But are they still rats?
Understanding the brain is one of the greatest goals of modern science. But parts of what we find out are more curious than we could have ever imagined. A new paper highlights one such discovery.
Researchers at the University of Stanford report that human neurons transplanted into newborn rats can grow and develop with the animal.
It’s a morning routine familiar for many of us: Get that mouth clean immediately after breakfast by using a harsh toothpaste applied by an abrasive toothbrush, followed by a rinse with a mouthwash so strong it makes you wince. Dr. Kami Hoss winces, too, when he hears patients describe these habits.
