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What if we’re not alone on Earth? Why We May Not Be Alone on Earth…

The shadow biosphere is a hypothetical microbial biosphere of Earth that would use radically different biochemical and molecular processes from that of currently known life.

00:00:00 Intro.
00:00:26 Bio.
00:00:55 Brilliant.
00:02:33 The Shadow Biosphere.
00:06:32 Multiple Abiogenesis.
00:13:20 Panspermic Shadow Biosphere.
00:16:40 How to find the Shadow Biosphere.
00:23:23 We don’t know the rules of Earth Life.
00:32:56 Mars life, could it be here?

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Scientific and technological advances have enabled us to zoom into the biological world. We can get down to the biomolecular scale, a domain where quantum phenomena can take place and therefore cannot be neglected.

Watch the Q&A with Alexandra here: https://youtu.be/_rElT2_NukY
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This talk was recorded at the Royal Institution on 28 October 2022.

Upon completing her doctoral studies in 2005 at the University of Oxford, Alexandra Olaya-Castro was subsequently awarded a three-year Junior Research Fellowship by Trinity College (Oxford), where she began her independent research career.

In November 2008 Alexandra Olaya-Castro obtained a five-year EPSRC Career Acceleration Fellowship that allowed her to start a research group in the Department of Physics and Astronomy of University College London. She was then appointed as a Lecturer in September 2011, was promoted to Reader in October 2015 and to full Professor in 2018.

Throughout her career Alexandra has made scientific contributions to the understanding of signatures and implications of quantum coherence in a variety of quantum systems that include exciton condensates in quantum wells, multi-qubit systems embedded in optical cavities and, her current focus, photo-activated biomolecular systems.

𝐓𝐡𝐞 𝐧𝐞𝐨𝐜𝐨𝐫𝐭𝐞𝐱 𝐬𝐭𝐚𝐧𝐝𝐬 𝐨𝐮𝐭 𝐚𝐬 𝐚 𝐬𝐭𝐮𝐧𝐧𝐢𝐧𝐠 𝐚𝐜𝐡𝐢𝐞𝐯𝐞𝐦𝐞𝐧𝐭 𝐨𝐟 𝐛𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐞𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧. 𝐀𝐥𝐥 𝐦𝐚𝐦𝐦𝐚𝐥𝐬 𝐡𝐚𝐯𝐞 𝐭𝐡𝐢𝐬 𝐬𝐰𝐚𝐭𝐡 𝐨𝐟 𝐭𝐢𝐬𝐬𝐮𝐞 𝐜𝐨𝐯𝐞𝐫𝐢𝐧𝐠 𝐭𝐡𝐞𝐢𝐫 𝐛𝐫𝐚𝐢𝐧, 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐬𝐢𝐱 𝐥𝐚𝐲𝐞𝐫𝐬 𝐨𝐟 𝐝𝐞𝐧𝐬𝐞𝐥𝐲 𝐩𝐚𝐜𝐤𝐞𝐝 𝐧𝐞𝐮𝐫𝐨𝐧𝐬 𝐰𝐢𝐭𝐡𝐢𝐧 𝐢𝐭 𝐡𝐚𝐧𝐝𝐥𝐞 𝐭𝐡𝐞 𝐬𝐨𝐩𝐡𝐢𝐬𝐭𝐢𝐜𝐚𝐭𝐞𝐝 𝐜𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐬 𝐚𝐧𝐝 𝐚𝐬𝐬𝐨𝐜𝐢𝐚𝐭𝐢𝐨𝐧𝐬 𝐭𝐡𝐚𝐭 𝐩𝐫𝐨𝐝𝐮𝐜𝐞 𝐜𝐨𝐠𝐧𝐢𝐭𝐢𝐯𝐞 𝐩𝐫𝐨𝐰𝐞𝐬𝐬. 𝐒𝐢𝐧𝐜𝐞 𝐧𝐨 𝐚𝐧𝐢𝐦𝐚𝐥𝐬 𝐨𝐭𝐡𝐞𝐫 𝐭𝐡𝐚𝐧 𝐦𝐚𝐦𝐦𝐚𝐥𝐬 𝐡𝐚𝐯𝐞 𝐚 𝐧𝐞𝐨𝐜𝐨𝐫𝐭𝐞𝐱, 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐡𝐚𝐯𝐞 𝐰𝐨𝐧𝐝𝐞𝐫𝐞𝐝 𝐡𝐨𝐰 𝐬𝐮𝐜𝐡 𝐚 𝐜𝐨𝐦𝐩𝐥𝐞𝐱 𝐛𝐫𝐚𝐢𝐧 𝐫𝐞𝐠𝐢𝐨𝐧 𝐞𝐯𝐨𝐥𝐯𝐞𝐝.

The brains of reptiles seemed to offer a clue. Not only are reptiles the closest living relatives of mammals, but their brains have a three-layered structure called a dorsal ventricular ridge, or DVR, with functional similarities to the neocortex.


The neocortex stands out as a stunning achievement of biological evolution. All mammals have this swath of tissue covering their brain, and the six layers of densely packed neurons within it handle the sophisticated computations and associations that produce cognitive prowess. Since no animals other than mammals have a neocortex, scientists have wondered how such a complex brain region evolved.

Now, however, by analyzing molecular details invisible to the human eye, scientists have refuted that view. By looking at patterns of gene expression in individual brain cells, researchers at Columbia University showed that despite the anatomical similarities, the neocortex in mammals and the DVR in reptiles are unrelated. Instead, mammals seem to have evolved the neocortex as an entirely new brain region, one built without a trace of what came before it. The neocortex is composed of new types of neurons that seem to have no precedent in ancestral animals.

That’s exactly what researchers in Germany set out to do, making use of “acoustic holograms” to form distinct 3D shapes out of particles suspended in water — all in “one shot,” said study lead author Kai Melde, a researcher from the Max Planck Institute, in a press release.

According to a study on the work, published last week in the journal Science Advances, the researchers were able to create a helix and a figure 8 out of silica gel beads, assembled biological cells into spherical clumps, and even provided a compelling concept for forming the shape of a dove in future experiments.

These acoustic holograms work by cleverly manipulating the pressure exerted by high frequency ultrasonic waves via the inexpensive use of a conventionally 3D-printed plate.

New research reveals clues about the physical and chemical characteristics of Earth when life is thought to have emerged.

About four billion years ago, the first signs of life emerged on Earth in the form of microbes. Although scientists are still determining exactly when and how these microbes appeared, it’s clear that the emergence of life is intricately intertwined with the chemical and physical characteristics of early Earth.

“It is reasonable to suspect that life could have started differently—or not at all—if the early chemical characteristics of our planet were different,” says Dustin Trail, an associate professor of earth and environmental sciences at the University of Rochester.

For a long time, scientists and engineers have drawn inspiration from the amazing abilities of animals and have sought to reverse engineer or reproduce these in robots and artificial intelligence (AI) agents. One of these behaviors is odor plume tracking, which is the ability of some animals, particularly insects, to home in on the source of specific odors of interest (e.g., food or mates), often over long distances.

A new study by researchers at University of Washington and University of Nevada, Reno has taken an innovative approach using (ANNs) in understanding this remarkable ability of flying insects. Their work, recently published in Nature Machine Intelligence, exemplifies how is driving groundbreaking new scientific insights.

“We were motivated to study a complex biological behavior, -tracking, that flying insects (and other animals) use to find food or mates,” Satpreet H. Singh, the lead author on the study, told Tech Xplore. “Biologists have experimentally studied many aspects of insect plume tracking in great detail, as it is a critical behavior for insect survival and reproduction. ”.

Tassili n’Ajjer is a national park in the Sahara desert, located on a vast plateau in southeastern Algeria, bordering Libya, Niger, and Mali. It covers an area of roughly 80,000 sq. km. and contains one of the most important collections of prehistoric rock art in the world; it was inducted into the UNESCO World Heritage Site list in 1982. In 1986, UNESCO declared the area a Biosphere Reserve.

The plateau is composed largely of sandstone, and the natural erosion has resulted in hundreds of natural rock arches and other spectacular land formations — the ‘forests of stone’. Because of the altitude and the water-holding properties of the sandstone, the vegetation is somewhat richer than in the surrounding desert, and includes scattered woodland of the endangered endemic species of the Saharan cypress — one of the oldest trees in the world — and the Saharan myrtle. The literal English translation of Tassili n’Ajjer is ‘plateau of rivers’. Relict populations of the West African crocodile persisted in the Tassili n’Ajjer until the twentieth century. Various other fauna still reside on the plateau, including Barbary sheep, the only surviving type of the larger mammals depicted in the rock art of the area.

The first signs of life emerged on Earth in the form of microbes about four billion years ago. While scientists are still determining exactly when and how these microbes appeared, it’s clear that the emergence of life is intricately intertwined with the chemical and physical characteristics of early Earth.

“It is reasonable to suspect that life could have started differently—or not at all—if the early chemical characteristics of our planet were different,” says Dustin Trail, an associate professor of and environmental sciences at the University of Rochester.

But what was Earth like billions of years ago, and what characteristics may have helped life to form? In a paper published in Science, Trail and Thomas McCollom, a research associate at the University of Colorado Boulder, reveal key information in the quest to find out. The research has important implications not only for discovering the but also in the search for life on other planets.