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A groundbreaking study reveals that Rhizobia bacteria can fix nitrogen in partnership with marine diatoms, a discovery that could have significant implications for agriculture and marine ecosystems.

Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet.

Atmospheric nitrogen gas is by far the largest pool of nitrogen, but plants cannot transform it into a usable form. Instead, crop plants like soybeans, peas and alfalfa (collectively known as legumes) have acquired Rhizobial bacterial partners that “fix” atmospheric nitrogen into ammonium. This partnership makes legumes one of the most important sources of proteins in food production.

A breakthrough study by the Institut Curie reveals that embryonic cell compaction in humans is caused by cell contraction, offering new insights to enhance assisted reproductive technology success rates.

In human development, the compaction of embryonic cells is a vital process in the early stages of an embryo’s formation. Four days post-fertilization, the cells tighten together, helping to form the embryo’s initial structure. If compaction is flawed, it can hinder the development of the essential structure needed for the embryo to attach to the uterus. During assisted reproductive technology (ART), this stage is meticulously observed before the embryo is implanted.

An interdisciplinary research team led by scientists at the Genetics and Developmental Biology Unit at the Institut Curie (CNRS/Inserm/Institut Curie) studying the mechanisms at play in this still little-known phenomenon has made a surprising discovery: human embryo compaction is driven by the contraction of embryonic cells. Compaction problems are therefore due to faulty contractility in these cells, and not a lack of adhesion between them, as was previously assumed. This mechanism had already been identified in flies, zebrafish, and mice, but is a first in humans.

Chemical reactions are complex mechanisms. Many different dynamic processes are involved, affecting both the electrons and the nucleus of the present atoms. Very often, the strongly coupled electron and nuclear dynamics induce radiation-less relaxation processes known as conical intersections. Such dynamics, which are at the basis of many biological and chemical relevant functions, are extremely difficult to detect experimentally.

Working To Reduce Global Catastrophic Biological Risks — Dr. Jaime Yassif, Ph.D. — VP, Global Biological Policy and Programs, Nuclear Threat Initiative.


Dr. Jaime Yassif, Ph.D. serves as Vice President of Global Biological Policy and Programs, at the Nuclear Threat Initiative (https://www.nti.org/about/people/jaim…) where she oversees work to reduce global catastrophic biological risks, strengthen biosecurity and pandemic preparedness, and drives progress in advancing global health security.

Prior to this, Dr. Yassif served as a Program Officer at the Open Philanthropy Project, where she led the initiative on Biosecurity and Pandemic Preparedness. In this role, she recommended and managed approximately $40 million in biosecurity grants, which rebuilt the field and supported work in several key areas, including: development of new biosecurity programming at several leading think tanks; cultivation of new talent through biosecurity leadership development programs; initiation of new biosecurity work in China and India; establishment of the Global Health Security Index; development of the Clade X tabletop exercise; and the emergence of a new discussion about global catastrophic biological risks.

Previously, Dr. Yassif was a Science and Technology Policy Advisor at the U.S. Department of Defense, where she focused on oversight of the Cooperative Threat Reduction Program and East Asia security issues. During this period, she also worked on the Global Health Security Agenda (GHSA) at the Department of Health and Human Services, where she helped lay the groundwork for the WHO Joint External Evaluations and the GHSA Steering Group.

Dr. Yassif’s previous experience includes work with Connecting Organizations for Regional Disease Surveillance, Chatham House, NTI, the Federation of American Scientists and the Tsinghua University Institute for International Studies.

The organic electrochemical transistor stands out as a tool for constructing powerful biosensors owing to its high signal transduction ability and adaptability to various geometrical forms. However, the performance of organic electrochemical transistors relies on stable and seamless interfaces with biological systems. This Review examines strategies to improve and optimize interfaces between organic electrochemical transistors and various biological components.

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If consciousness is 100% physical, we would have to conclude that the same kind of consciousness that we experience as humans can be generated by non-biological entities (eventually). Conversely, if non-biological consciousness would somehow, someday, prove impossible, then consciousness would have to embed some nonphysical aspect. But how would we ever know?

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Andy Clark is a British philosopher who is Professor of Cognitive Philosophy at the University of Sussex.

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Closer To Truth, hosted by Robert Lawrence Kuhn and directed by Peter Getzels, presents the world’s greatest thinkers exploring humanity’s deepest questions. Discover fundamental issues of existence. Engage new and diverse ways of thinking. Appreciate intense debates. Share your own opinions. Seek your own answers.

Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid “engineered living materials” are made by embedding cells in an inanimate matrix that’s formed in a desired shape. Now, researchers report in ACS Central Science that they have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

Summary: Researchers leveraged deep reinforcement learning (DRL) to enable a robot to adaptively switch gaits, mimicking animal movements like trotting and pronking, to traverse complex terrains effectively. Their study explores the concept of viability—or fall prevention—as a primary motivator for such gait transitions, challenging previous beliefs that energy efficiency is the key driver.

This novel approach not only enhances the robot’s ability to handle challenging terrains but also provides deeper insights into animal locomotion. The team’s findings suggest that prioritizing fall prevention may lead to more agile and efficient robotic and biological movement across uneven surfaces.