The idea is simple. First, they take an arm from a dead rat and put it through a process of decellularization using detergents. This leaves behind a white scaffold. The scaffold is key because no artificial reconstructions come close to replicating the intricacies of a natural one.
“Researchers are considering how CRISPR could or should be deployed on organisms in the wild. Much of the attention has focused on a method called gene drive, which can quickly sweep an edited gene through a population. The work is at an early stage, but such a technique could be used to wipe out disease-carrying mosquitoes or ticks, eliminate invasive plants or eradicate herbicide resistance in pigweed, which plagues some US farmers.” Read more
“The Howard Hughes Medical Institute (HHMI) announced today that 26 of the nation’s top biomedical researchers will become HHMI investigators and will receive the flexible support necessary to move their research in creative new directions. The initiative represents an investment in basic biomedical research of $153 million over the next five years.”
“The point being, science needs room to figure out exactly what this technology is capable of doing. Right now, researchers have a ton of potential on their hands, but not a lot of agreement about how far that potential reaches.” Read more
David Cyranosk & Sara Reardon - Nature.com
In a world first, Chinese scientists have reported editing the genomes of human embryos. The results are published1 in the online journal Protein & Cell and confirm widespread rumours that such experiments had been conducted — rumours that sparked a high-profile debate last month2, 3 about the ethical implications of such work. Read more
By David Cyranoski — Scientific American
In a Comment published on March 12 in Nature, Edward Lanphier, chairman of the Alliance for Regenerative Medicine in Washington DC, and four co-authors call on scientists to agree not to modify human embryos — even for research.
“Such research could be exploited for non-therapeutic modifications. We are concerned that a public outcry about such an ethical breach could hinder a promising area of therapeutic development,” write Lanphier and his colleagues, who include Fyodor Urnov, a pioneer in gene-editing techniques and scientist at Sangamo BioSciences in Richmond, California. Many groups, including Urnov’s company, are already using gene-editing tools to develop therapies that correct genetic defects in people (such as by editing white blood cells). They fear that attempts to produce ‘designer babies’ by applying the methods to embryos will create a backlash against all use of the technology.Read more
Kurzweil AI
Bacteria within you — which outnumber your own cells about 100 times — may be affecting both your cravings and moods to get you to eat what they want, and may be driving you toward obesity.
That’s the conclusion of an article published this week in the journal BioEssays by researchers from UC San Francisco, Arizona State University and University of New Mexico from a review of the recent scientific literature.
By Zak Cheney-Rice — News.Mic
The news: Russian cosmonauts have discovered something remarkable clinging to the outside of the International Space Station: living organisms.
The microscopic creatures appeared during a space walk intended to clean the vessel’s surface, and were allegedly identified — incredibly — as a type of sea plankton. This is big: According to Sploid, Russian scientists are both “shocked by [the] discovery and can’t really explain how [it] is possible.”
