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Jan 14, 2025

Single Gene Links Autism, Epilepsy via Brain Circuit Development

Posted by in categories: genetics, neuroscience

New research uncovers how neuropilin2 gene mutations disrupt brain balance, linking inhibitory neuron migration to autism and epilepsy. Study offers insights for targeted therapies.


Source: UCR

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

Neuropilin2 controls migration of inhibitory neurons as well as the formation and maintenance of synaptic connections in excitatory neurons — two crucial components of brain activity.

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