Toggle light / dark theme

Single Gene Links Autism, Epilepsy via Brain Circuit Development

New research uncovers how neuropilin2 gene mutations disrupt brain balance, linking inhibitory neuron migration to autism and epilepsy. Study offers insights for targeted therapies.


Source: UCR

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

Neuropilin2 controls migration of inhibitory neurons as well as the formation and maintenance of synaptic connections in excitatory neurons — two crucial components of brain activity.