Lifeboat Foundation

Who Needs a Man-Month?

A surprising class of blood cell not typically associated with immunity plays a role in shaping the durability of immunity to vaccination, new research suggests.

🧬 🧑🏻‍🔬 By Prof. Itzhak Fishov, et al.

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Phenotypic variability in isogenic bacterial populations is a remarkable feature that helps them cope with external stresses, yet it is incompletely understood. This variability can stem from gene expression noise and/or the unequal partitioning of low-copy-number freely diffusing proteins during cell division. Some high-copy-number components are transiently associated with almost immobile large assemblies (hyperstructures) and may be unequally distributed, contributing to bacterial phenotypic variability. We focus on the nucleoid hyperstructure containing numerous DNA-associated proteins, including the replication initiator DnaA. Previously, we found an increasing asynchrony in the nucleoid segregation dynamics in growing E. coli cell lineages and suggested that variable replication initiation timing may be the main cause of this phenomenon.

From the early days of quantum mechanics, scientists have thought that all particles can be categorized into one of two groups—bosons or fermions—based on their behavior.

However, new research by Rice University physicist Kaden Hazzard and former Rice graduate student Zhiyuan Wang shows the possibility of particles that are neither bosons nor fermions. Their study, published in Nature, mathematically demonstrates the potential existence of paraparticles that have long been thought impossible.

“We determined that new types of particles we never knew of before are possible,” said Hazzard, associate professor of physics and astronomy.

A breakthrough in decoding the growth process of hexagonal boron nitride (hBN), a 2D material, and its nanostructures on metal substrates could pave the way for more efficient electronics, cleaner energy solutions and greener chemical manufacturing, according to new research from the University of Surrey published in the journal Small.

Only one atom thick, hBN—often nicknamed “white graphene”—is an ultra-thin, super-resilient material that blocks electrical currents, withstands extreme temperatures and resists chemical damage. Its unique versatility makes it an invaluable component in advanced electronics, where it can protect delicate microchips and enable the development of faster, more efficient transistors.

Going a step further, researchers have also demonstrated the formation of nanoporous hBN, a novel material with structured voids that allows for selective absorption, advanced catalysis and enhanced functionality, vastly expanding its potential environmental applications. This includes sensing and filtering pollutants—as well as enhancing advanced energy systems, including hydrogen storage and electrochemical catalysts for fuel cells.

Autophagy, the cell’s essential housekeeping process, involves degrading and recycling damaged organelles, proteins, and other components to prevent clutter. This vital mechanism, found in all life forms from single-celled organisms to plants and animals, is key to maintaining cellular homeostasis. Its disruption is linked to many known diseases in humans, such as Alzheimer’s, Parkinson’s, and cancer.

Though understanding autophagy in detail is important from medical and biological perspectives, it is not a one-size-fits-all process. There are several forms of autophagy that differ in how the components to be degraded are transported to the lysosomes or vacuoles—the organelles that serve as the cell’s waste disposal and recycling centers.

Autophagy targets a range of intracellular components, including a part of the nucleus that stores important chromosomes. However, the physiological significance of autophagic degradation of the nucleus remains unknown.

The LUX ZEPLIN (LZ) Dark Matter experiment is a large research effort involving over 200 scientists and engineers at 40 institutions worldwide. Its key objective is to search for weakly interacting massive particles (WIMPs) by analyzing data collected by the LZ detector, situated at the Sanford Underground Research Facility in South Dakota.

The LZ Collaboration recently released the results of the first experimental run of the LZ dark matter experiment. These results, published in Physical Review Letters, set new constraints on the interactions between dark matter and other particles, which could inform future searches for weakly-interacting dark matter candidates.

“There is no reason to believe that dark matter will interact with regular matter in the simplest way, so it is important to consider more complex interactions,” Sam Eriksen, co-author of the paper, told Phys.org.

Using NASA’s Fermi space telescope, Italian astronomers have observed a radio source known as 3C 216. As a result, they detected increased gamma-ray activity from this source, including a strong outburst. The finding is reported in a research paper published on the arXiv preprint server.

3C 216 is an extragalactic radio source at a redshift of approximately 0.67, with a projected linear size of about 182,500 light years. It has an overall steep radio spectrum and a relatively compact morphology. Therefore, it is classified as a compact steep spectrum (CSS) object.

Previous observations of 3C 216 have found that it is a radio galaxy consisting of a central component surrounded by a more extended structure, and has an inner relativistic jet. It turns out that this galaxy is associated with gamma-ray source 4FGL J0910.0+4257.

In an unprecedented new study, researchers have shown neurotransmitters in the human brain are released during the processing of the emotional content of language, providing new insights into how people interpret the significance of words.

The work, conducted by an international team led by Virginia Tech scientists, offers deeper understanding into how language influences human choices and mental health.

Spearheaded by computational neuroscientist Read Montague, a professor of the Fralin Biomedical Research Institute at VTC and director of the institute’s Center for Human Neuroscience Research, the study represents a first-of-its-kind exploration of how neurotransmitters process the emotional content of language—a uniquely human function.