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Mature or nearly mature fruits of Piper longum are used as a spice, valued for their commercial and industrial applications, as well as in traditional Chinese medicine for their multiple effects, such as dispelling cold and relieving pain.

Given their long history of medicinal use, the fruits of P. longum present an opportunity to explore their therapeutic constituents. However, the chemical components of traditional Chinese medicines are often complex, making the efficient discovery of novel active compounds a challenging task in natural product research.

To address this challenge, a research team led by Prof. Haji Akber Aisa from the Xinjiang Technical Institute of Physics & Chemistry of the Chinese Academy of Sciences isolated 12 dimeric amide alkaloid enantiomers with anti-inflammatory and antidiabetic effects from P. longum fruits using a molecular network-based dereplication strategy. This study was published in the Journal of Agricultural and Food Chemistry.

The large-scale renewable energy storage sphere is set to get a massive boost with the development of a 1 GWh molten salt storage system, which will be capable of powering approximately 100,000 homes for 10 hours with an efficiency of up to 90%.

This breakthrough is the result of a collaboration between Danish thermal energy storage developer Hyme Energy and Swiss fluid engineering specialist Sulzer.

More than 80 years ago, Erwin Schrödinger, a theoretical physicist steeped in the philosophy of Schopenhauer and the Upanishads, delivered a series of public lectures at Trinity College, Dublin, which eventually came to be published in 1944 under the title “What is Life?”

Now, in the 2025 International Year of Quantum Science and Technology, Philip Kurian, a and founding director of the Quantum Biology Laboratory (QBL) at Howard University in Washington, D.C., has used the laws of quantum mechanics, which Schrödinger postulated, and the QBL’s discovery of cytoskeletal filaments exhibiting quantum optical features, to set a drastically revised upper bound on the computational capacity of carbon-based life in the entire history of Earth.

Published in Science Advances, Kurian’s latest work conjectures a relationship between this information-processing limit and that of all matter in the observable universe.

Astrophysicists at the University of Colorado’s JILA, National Institute of Science and Technology, have conducted an experiment to produce benzene the way theories have predicted it is produced in interstellar space and found it did not produce any benzene. The research by G. S. Kocheril, C. Zagorec-Marks and H. J. Lewandowski is published in the journal Nature Astronomy.

Research efforts in the 1990s led to theories suggesting that ion-molecule collisions could be one of the main ways that interstellar forms. Such theories are important for space research because it is believed that benzene is a precursor to the formation of interstellar , which are believed to hold cosmic carbon, which is important for many reasons but mainly because of the role it might have played in the development of carbon-based lifeforms.

Testing of theories that lead to the creation of benzene in has not been done before because of the difficulty in creating the conditions that exist in such an environment. In their paper, and during a speech at a recent symposium, the group stated that they had the equipment necessary to carry out such an experiment in their lab at JILA.

A team of management researchers affiliated with several institutions in the U.S. has found that minority Lyft drivers in Florida are more likely to be stopped and ticketed for speeding and to be more highly fined than white drivers.

In their study published in the journal Science, the group analyzed data for more than 200,000 Lyft drivers working in Florida over the years 2017 to 2020.

Dean Knox and Jonathan Mummolo with the University of Pennsylvania’s Wharton School of Management and Princeton’s School of Public and International Affairs, respectively, have published a Perspective piece in the same journal, outlining the difficulty in finding suitable environments for conducting profiling studies in public settings and the results of the new effort.

In late 2023, Wojciech Brylinski was analyzing data from the NA61/SHINE collaboration at CERN for his thesis when he noticed an unexpected anomaly—a strikingly large imbalance between charged and neutral kaons in argon–scandium collisions. He found that, instead of being produced in roughly equal numbers, charged kaons were produced 18.4% more often than neutral kaons.

This suggested that the so-called “isospin ” between up and down quarks might be broken by more than expected due to the differences in their electric charges and masses—a discrepancy that existing would struggle to explain. Known sources of isospin asymmetry only predict deviations of a few percent.

“When Wojciech got started, we thought it would be a trivial verification of the symmetry,” says Marek Gaździcki, who was spokesperson of NA61/SHINE at the time of the discovery. “We expected the symmetry to be closely obeyed—although we had previously measured these types of discrepancies at the NA49 experiment, they had large uncertainties and were not significant.”

Conventional curved lenses, which direct light by refraction in glass or plastic, are often bulky and heavy, offering only limited control of light waves. Metasurfaces, in contrast, are flat and consist of an array of tiny structures known as meta-atoms. Meta-atoms influence light at a subwavelength scale and thus allow for highly precise control of the phase, amplitude, and polarization of light.

“Using metasurfaces, we can influence the temporal shift, intensity, and direction of oscillation of light waves in a targeted way,” says Dr. Maryna Leonidivna Meretska, Group Leader at KIT’s Institute of Nanotechnology.

“Thanks to its multiplex control capabilities, i.e., the simultaneous and targeted influencing of various parameters, a single metasurface can replace multiple . Thus, the size of the optical system can be reduced without affecting its performance.”

Researchers at the University of Illinois Urbana-Champaign have unlocked new insights into the turbulent behavior of hypersonic flows by using advanced 3D simulations.

Leveraging supercomputing power and custom-built software, they discovered unexpected instabilities and flow breaks around cone-shaped models at Mach 16, disturbances never seen before in previous 2D or experimental studies. These findings could significantly impact the design of future hypersonic vehicles by helping engineers understand how extreme speeds interact with surface geometries in new ways.

Hypersonic Flows and New Discoveries.