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New therapeutic target identified for neuroendocrine tumors in the gastrointestinal tract

Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. They’re scattered throughout the body, including the stomach, intestines, pancreas and lungs. Tumors that arise from these cells are called neuroendocrine tumors and are often rare and slow growing.

Around 70% of all neuroendocrine tumors arise in the pancreas or gastrointestinal tract and are known as gastroenteropancreatic neuroendocrine tumors, or GEP-NETs. Targeting these tumors is often challenging because cells become resistant to treatment.

In a recent study published in the journal Cell Reports Medicine, University of Michigan researchers have identified a new target that can suppress tumor growth. Their findings may lead to new treatment methods for GEP-NETs.

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