This Research Letter offers a creative approach to sepsis based on a naturally occurring efferocytosis-enhancing RNA
Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis by Alessandra Ciullo & team: https://doi.org/10.1172/jci.insight.
The image shows exposure to TY2 increases E. coli clearance by bone-marrow derived macrophages as indicated by fluorophore as a reporter of efferocytosis (green).
Address correspondence to: Alessandra Ciullo, Smidt Heart Institute, Cedars-Sinai Medical Center, 8,700 Beverly Blvd., Los Angeles, California 90,048, USA. Email: [email protected].
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Smidt heart institute, cedars-sinai medical center, los angeles, california, USA.
