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TY2 is protective in a rat model of MI and in a model of cecal ligation and puncture–induced sepsis

This Research Letter offers a creative approach to sepsis based on a naturally occurring efferocytosis-enhancing RNA

Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis by Alessandra Ciullo & team: https://doi.org/10.1172/jci.insight.

The image shows exposure to TY2 increases E. coli clearance by bone-marrow derived macrophages as indicated by fluorophore as a reporter of efferocytosis (green).


Address correspondence to: Alessandra Ciullo, Smidt Heart Institute, Cedars-Sinai Medical Center, 8,700 Beverly Blvd., Los Angeles, California 90,048, USA. Email: [email protected].

Find articles by Ciullo, A. in: | Google Scholar

Smidt heart institute, cedars-sinai medical center, los angeles, california, USA.

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