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Autism’s Link to Parkinson’s Risk May Finally Be Explained

People with autism may be up to six times more likely to develop Parkinson’s disease in later life. New research offers a potential explanation based on the role of transporter molecules that recycle unused dopamine in the brain.

Dopamine is a neurotransmitter crucial for managing movement and executive functions, and for reinforcing behavior. It’s well known that Parkinson’s is characterized by a drop in dopamine levels, while disruptions in the transport of the chemical have also been linked to autism.

With that context, researchers led by a team from the University of Missouri in the US took a novel approach using a technology known as a DaT SPECT scan, which is typically used to diagnose Parkinson’s in much older people.

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