A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report in Science, and it reduces the risk of leukemia.

The findings offer insight into why some people are naturally more resistant to clonal expansion and age-related blood cancers despite acquiring risky mutations.

Learn more in a new Science Perspective.

A genome-wide association study identifies a genetic variant that reduces the risk of leukemia.

Francisco Caiado and Markus G. Manz Authors Info & Affiliations

Science

Vol 391, Issue 6780