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Brain cancer cells can be ‘reprogrammed’ to stop them from spreading

Scientists have found a way to stop brain cancer cells spreading by essentially ‘freezing’ a key molecule in the brain.

The finding could pave the way for a new type of treatment for , the most aggressive form of brain cancer, although extensive testing will be required before it can be trialed in patients. Glioblastoma is the most common type of brain cancer, with a five-year survival rate of just 15%.

The researchers, from the University of Cambridge, found that rely on the flexibility of (HA)—a sugar-like polymer that makes up much of the brain’s supporting structure—to latch onto receptors on the surface of cancer cells to trigger their spread throughout the brain.

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