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Immune cells turn into ‘mini-Hulks’ to push away tissue and make space when migrating

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.

Research by the Sixt group at the Institute of Science and Technology Austria (ISTA) unveils how immune cells use their cytoskeleton to exert forces on their surrounding environment to push their way through tissues.

The findings were published in Nature Immunology.

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